@article{TackeZimonyiHegeduesStreckeretal.1980, author = {Tacke, Reinhold and Zimonyi-Heged{\"u}s, E. and Strecker, M. and Heeg, E. and Berndt, B. and Langner, R.}, title = {Sila-Analogon des Tiemoniumiodids}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63669}, year = {1980}, abstract = {Sila-Tiemoniumiodid (16b), ein Sila-Analogon des Anticholinergicums Tiemoniumiodid (16a), und das Sila-Analogon 14b der entsprechenden Tiemonium-Base 14a wurden erstmalig synthetisiert.14b und 16b sowie die Vorstufen 10-13 und 15 wurden in ihren physikalischen und chemischen Eigenschaften charakterisiert und in ihrer Struktur durch Elementaranalysen sowie \(^1\)H-NMR- und Massenspektren sichergestellt. Die spasmolytischen Eigenschaften der Paare 14a/14b und 16a/16b wurden am isolierten Meerschweinchendarm vergleichend untersucht.}, subject = {Anorganische Chemie}, language = {de} } @article{TackeWuttkeHenke1992, author = {Tacke, Reinhold and Wuttke, F. and Henke, H.}, title = {Zur Stereochemie der mikrobiellen Reduktion von rac-Acetyl( t-butyl)methylphenylsilan mit Trigonopsis variabilis (DSM 70714) und Corynebacterium dioxydans (ATCC 21766): Aufkl{\"a}rung der absoluten Konfiguration der Biotransformationsprodukte (SiR,CR)- und ( SiS ,CR)-t-Butyl( 1-hydroxyethyl)methylphenylsilan}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-64176}, year = {1992}, abstract = {No abstract available}, subject = {Anorganische Chemie}, language = {en} } @article{TackeWiesenbergerLopezMrasetal.1992, author = {Tacke, Reinhold and Wiesenberger, Frank and Lopez-Mras, Angel and Sperlich, J{\"o}rg and Mattern, G{\"u}nter}, title = {Neuartige zwitterionische λ5-Spirosilicate: Synthese und Kristallstruktur von Bis[1,2-benzoldiolato(2-)][2-(dimethylammonio)phenyl]silicat sowie Synthese von Bis[2,3-naphthalindiolato(2-)][2-(dimethylammonio)phenyl]silicat-Hemiacetonitril-Solvat}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86916}, year = {1992}, abstract = {No abstract available.}, subject = {Silicate}, language = {de} } @article{TackeWiesenberger1991, author = {Tacke, Reinhold and Wiesenberger, Frank}, title = {(Acetoxymethyl)methylphenylgerman: Synthese, thermisches Verhalten und olfaktorische Eigenschaften}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86927}, year = {1991}, abstract = {No abstract available.}, subject = {Chemische Synthese}, language = {de} } @article{TackeWiesenbergerBeckeretal.1992, author = {Tacke, Reinhold and Wiesenberger, F. and Becker, B. and Rohr-Aehle, R. and Schneider, P. B. and Ulbrich, U. and Sarge, S. M. and Cammenga, H. K. and Koslowski, T. and Niessen, W. von}, title = {Ester von (Hydroxymethyl)diorganylsilanen: Synthese und thermisch induzierte Umlagerung}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-64188}, year = {1992}, abstract = {Twenty silanes of the type R\(^1\)R\(^2\)Si(H)CH\(_2\)OR\(^3\) (A) were syn- and entropy of activation) of these reactions were studied by thesized {R\(^1\), R\(^2\) = Me, Ph, 1-naphthyl, PhCH\(_2\), Me\(_3\)SiCH\(_2\); OR\(^3\) means of d{\"u}ferential scanning calorimetry (DSC). In addition, = OC(O)Me, OC(O)Ph, OC(O)CF\(_3\) , OS(0)\(_2\)CF\(_3\), OP(O)Ph\(_2\), the kinetics of all reactions were investigated by 1H-NMR OC(O)Cl, and studied for their thermal behaviour. The silanes spectroscopy. The transition state of the rearrangement was A undergo a thermally induced rearrangement to give the investigated by an ab initio study based on the model comcorresponding silanes R\(^1\)R\(^2\)Si(OR\(^3\))Me (B). For compounds with pound H\(_3\)SiCH\(_2\)OC(O)H (-> MeH\(_2\)SiOC(O)H]. The theoretical OR3 = OC(O)Cl, an additional decarboxylation takes place to data and the experimentally obtained energetic and kinetic yield the chlorosilanes R1R2Si(Cl)Me. Except for the deriva- data are discussed in terms of mechanistic aspects of the retives with OR\(^3\) = OC(O)Cl, the energetic (reaction enthalpy) arrangement reaction A -> B. and kinetic data (reaction order, frequency factor, enthalpy ...}, subject = {Anorganische Chemie}, language = {de} } @article{TackeWannagat1975, author = {Tacke, Reinhold and Wannagat, U.}, title = {Sila-Analoga des Mephenhydramins}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63525}, year = {1975}, abstract = {Sila-Analogues A 2, B 2 and C 2 of the drug mephenhydramine from the class of benzhydryl ethers were synthesized for the first time by the steps shown in scheme 1, and they and their precursors I-V characterized by their physical {table 1) and chemical properties, and their structures confirmed by NMR, n1ass and infrared spectroscopy (tables 3-5). Their physiological effects were investigated a.nd compared -with those of the parent carbon compounds (section 5).}, subject = {Anorganische Chemie}, language = {de} } @article{TackeWannagat1976, author = {Tacke, Reinhold and Wannagat, U.}, title = {Sila-Analoga des Chlorphenoxamins und des Clofenetamins}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63531}, year = {1976}, abstract = {Sila-ana.logues A 2 and B 2 of two drugs from the benzhydryl ether class, chlorphenoxamine and clofenetamine, were synthesized for the first time by the steps shown in scheme 1. They and their precursors I-VI v;rere characterized by their physical (Table 1) and chemical properties and their structures confirmed by n.m.r., mass and infrared spectroscopy (Tab]es 2-5). Their physiological effects were invest.igated and compared with those of the carbon analogues (Chapter 5).}, subject = {Anorganische Chemie}, language = {de} } @article{TackeWannagat1976, author = {Tacke, Reinhold and Wannagat, U.}, title = {Sila-Analoga des Mebrophenhydramins}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63542}, year = {1976}, abstract = {Sila-analogues A 2, B 2 and C 2 of the drug mebrophenhydramine from the class of benzhydryl ethers -were synthesized for the first time by the steps shown in scheme 1, and they and their precurso:rs I-Ill were characterized by their physical (Table 1) and chemical properties, a.nd their structures confirmed by NMR, mass and infrared spectroscopy (Tables 3-5). The histaminolytic and anticholinergic effects of A 2 and C 2 were investigated and compared with some structure-activity relationships of analogue carbon compounds.}, subject = {Anorganische Chemie}, language = {de} } @article{TackeWannagat1976, author = {Tacke, Reinhold and Wannagat, U.}, title = {Sila-Analogon des Cicloniumbromids}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63556}, year = {1976}, abstract = {Sila-Analogues B 2 and A 2 of the spasmolytic ciclonium bromide (B 1) respectively the corresponding free base A 1 were synthesized for the first time according to the reaction steps sho·wn in scheme 1, and they and their precursors I and II were characterized by ph;ysical (Table 1} and chemical properties and their structures confirmed by NMR, and mass spectroscopy (Tables 2 and 3}. The pharmacological effects of A 2 and B 2 were investigated and compared with those of the parent carbon compound B 1 (chapter 5).}, subject = {Anorganische Chemie}, language = {de} } @article{TackeWannagat1976, author = {Tacke, Reinhold and Wannagat, U.}, title = {Derivate des Sila-Mephenhydramins und Sila-Chlorphenoxamins}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-63562}, year = {1976}, abstract = {Derivatives A and B of the two sila-antihistam.ines silamephenhydramine and sila-chlorphenoxamine were synthesized for the first time by the steps shown in scheme 1. They and their precursors III and IV were characterized by their physical (Table 1) and chemical properties and their structures confirmed by NMR and mass spectroscopy (Tables 2 and 3). Their pharmacological effects were investigated and compared with those of the corresponding sila-antihistamines.}, subject = {Anorganische Chemie}, language = {de} }