@techreport{MeyerJobLaneretal.2022, author = {Meyer, Constantin and Job, Hubert and Laner, Peter and Omizzolo, Andrea and Kollmann, Nadia and Clare, Jasmin and Vesely, Philipp and Riedler, Walter and Plassmann, Guido and Coronado, Oriana and Praper Gulič, Sergeja and Gulič, Andrej and Koblar, Simon and Teofili, Corrado and Rohringer, Verena and Schoßleitner, Richard and Ainz, Gerhard}, title = {OpenSpaceAlps Planungshandbuch: Perspektiven f{\"u}r eine konsistente Freiraumsicherung im Alpenraum}, doi = {10.25972/OPUS-27307}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-273070}, pages = {114}, year = {2022}, abstract = {Im Alpenraum l{\"a}sst sich nach wie vor die kontinuierliche Inanspruchnahme von Freir{\"a}umen f{\"u}r Siedlungsfl{\"a}chen und technische Infrastrukturen und die damit verbundene Bodenversiegelung beobachten. Dies f{\"u}hrt in erster Linie zum Verlust von landwirtschaftlichen Fl{\"a}chen. Je nach Ausmaß der Bebauung kommt es auch zu einer verst{\"a}rkten Landschaftszerschneidung, die zur Isolierung nat{\"u}rlicher Lebensr{\"a}ume und zur Einschr{\"a}nkung des {\"o}kologischen Verbundes sowie zu weiteren negativen Folgewirkungen f{\"u}hrt. Das OpenSpaceAlps Projekt hat sich dieser Thematik angenommen und, basierend auf kooperativen Verfahren in mehreren Pilotregionen, Handlungsans{\"a}tze und Strategien f{\"u}r eine nachhaltige Sicherung von Freir{\"a}umen entwickelt. Dieses Handbuch stellt eine Handlungs- und Entscheidungshilfe f{\"u}r verschiedene Akteure/Akteurinnen dar, allen voran Planer*innen in {\"o}ffentlichen Planungsbeh{\"o}rden. Ausgehend von einer Analyse der Herausforderungen und Rahmenbedingungen im Alpenraum, werden in diesem Handbuch zentrale „Prinzipien" der Freiraumplanung vorgestellt und verglichen. Außerdem werden integrierte Planungsstrategien f{\"u}r verschiedene Raumkategorien diskutiert.}, subject = {Raumordnung}, language = {de} } @techreport{OPUS4-35963, title = {Platelets - Molecular, cellular and systemic functions in health and disease}, editor = {Nieswandt, Bernhard}, organization = {Collaborative Research Centre/Transregio 240}, doi = {10.25972/OPUS-35963}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-359636}, pages = {25}, year = {2024}, abstract = {Besides their central role in haemostasis and thrombosis, platelets are increasingly recognised as versatile effector cells in inflammation, the innate and adaptive immune response, extracellular matrix reorganisation and fibrosis, maintenance of barrier and organ integrity, and host response to pathogens. These platelet functions, referred to as thrombo-inflammation and immunothrombosis, have gained major attention in the COVID-19 pandemic, where patients develop an inflammatory disease state with severe and life-threatening thromboembolic complications. In the CRC/TR 240, a highly interdisciplinary team of basic, translational and clinical scientists explored these emerging roles of platelets with the aim to develop novel treatment concepts for cardiovascular disorders and beyond. We have i) unravelled mechanisms leading to life-threatening thromboembolic complica-tions following vaccination against SARS-CoV-2 with adenoviral vector-based vaccines, ii) identified unrecognised functions of platelet receptors and their regulation, offering new potential targets for pharmacological intervention and iii) developed new methodology to study the biology of megakar-yocytes (MKs), the precursor cells of platelets in the bone marrow, which lay the foundation for the modulation of platelet biogenesis and function. The projects of the CRC/TR 240 built on the unique expertise of our research network and focussed on the following complementary fields: (A) Cell bi-ology of megakaryocytes and platelets and (B) Platelets as regulators and effectors in disease. To achieve this aim, we followed a comprehensive approach starting out from in vitro systems and animal models to clinical research with large prospective patient cohorts and data-/biobanking. Despite the comparably short funding period the CRC/TR 240 discovered basic new mechanisms of platelet biogenesis, signal transduction and effector function and identified potential MK/platelet-specific molecular targets for diagnosis and therapy of thrombotic, haemorrhagic and thrombo-inflammatory disease states.}, subject = {Thrombozyt}, language = {en} } @techreport{BaumgartBredebachHermetal.2022, author = {Baumgart, Michael and Bredebach, Patrick and Herm, Lukas-Valentin and Hock, David and Hofmann, Adrian and Janiesch, Christian and Jankowski, Leif Ole and Kampik, Timotheus and Keil, Matthias and Kolb, Julian and Kr{\"o}hn, Michael and Pytel, Norman and Schaschek, Myriam and St{\"u}bs, Oliver and Winkelmann, Axel and Zeiß, Christian}, title = {Plattform f{\"u}r das integrierte Management von Kollaborationen in Wertsch{\"o}pfungsnetzwerken (PIMKoWe)}, editor = {Winkelmann, Axel and Janiesch, Christian}, issn = {2199-0328}, doi = {10.25972/OPUS-29335}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-293354}, pages = {248}, year = {2022}, abstract = {Das Verbundprojekt „Plattform f{\"u}r das integrierte Management von Kollaborationen in Wertsch{\"o}pfungsnetzwerken" (PIMKoWe - F{\"o}rderkennzeichen „02P17D160") ist ein Forschungsvorhaben im Rahmen des Forschungsprogramms „Innovationen f{\"u}r die Produktion, Dienstleistung und Arbeit von morgen" der Bekanntmachung „Industrie 4.0 - Intelligente Kollaborationen in dynamischen Wertsch{\"o}pfungs-netzwerken" (InKoWe). Das Forschungsvorhaben wurde mit Mitteln des Bundesministeriums f{\"u}r Bildung und Forschung (BMBF) gef{\"o}rdert und durch den Projekttr{\"a}ger des Karlsruher Instituts f{\"u}r Technologie (PTKA) betreut. Ziel des Forschungsprojekts PIMKoWe ist die Entwicklung und Bereitstellung einer Plattforml{\"o}sung zur Flexibilisierung, Automatisierung und Absicherung von Kooperationen in Wertsch{\"o}pfungsnetzwerken des industriellen Sektors.}, subject = {Blockchain}, language = {de} } @techreport{Hommers1988, author = {Hommers, Wilfried}, title = {Recompense as Stimulus and Response: Toward an Exchange of Law and Psychology}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43743}, year = {1988}, abstract = {Recompense denotes a more or less complete undoing of a harm which may combine the tWO aspects: compensation for the victim and the apology of the harmdoer. The present empirical research on recompense started with an analysis of the judgmental structures of recompense in legal thought and law, as such analysis has been neglected in prior research. The obtained results on recompense as stimulus and response reinforce the general idea of the present approach of using the framework of law and legal history in the empirical research of cognitive science. Since the traditionahelationship of jurisprudence and psychology is reversed by that research strategy, law and psychology appear to interact mutually, and a more comprehensive concept of legal psychology is implemented.}, language = {en} } @techreport{NordPetzke2023, author = {Nord, Ilona and Petzke, Judith}, title = {Religious Education in the digital change. Concepts and reflections from a German context}, edition = {revised version}, doi = {10.25972/OPUS-32858}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-328582}, pages = {30}, year = {2023}, abstract = {The article presents results from the project Religious Education Laboratory digital (RELab digital): At a time when exclusive access to religion in the classroom seems less and less plausible, the concept of digital religion education we propose leads back to the existential needs for religion. It can refer to the thematic fields of digital religions, which in turn are not new for religious education, but remix its traditions and themes in the mirror of transforming communication cultures: authority, community, truth, communication, autonomy, religion, identity, and ritual. Chapter 1 contains a description of the project structure. Chapter 2 is dedicated to the pedagogical challenge of teaching Religious Education (RE) in the digital change. Chapter 3 reflects from a pedagogical standpoint on empirical findings of the project, which were developed in the context of classroom observations and interviews. Chapter 4 focuses on topics related to the profession of teachers: What self-concepts are pursued by teachers of Religious Education and/or can be reconstructed through the way they act in the classroom? How can the often critical perceptions of teachers who use digital media in religious education be put to good use in the future? The conclusion bundles the most important insights and highlights examples of further research.}, subject = {Digitalisierung}, language = {en} } @techreport{NordPetzke2023, author = {Nord, Ilona and Petzke, Judith}, title = {Religious Education in the digital change. Concepts and reflections from a German context}, doi = {10.25972/OPUS-32280}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-322802}, pages = {30}, year = {2023}, abstract = {The article presents results from the project Religious Education Laboratory digital (RELab digital): At a time when exclusive access to religion in the classroom seems less and less plausible, the concept of digital religion education we propose leads back to the existential needs for religion. It can refer to the thematic fields of digital religions, which in turn are not new for religious education, but remix its traditions and themes in the mirror of transforming communication cultures: authority, community, truth, communication, autonomy, religion, identity, and ritual. Chapter 1 contains a description of the project structure. Chapter 2 is dedicated to the pedagogical challenge of teaching Religious Education (RE) in the digital change. Chapter 3 reflects from a pedagogical standpoint on empirical findings of the project, which were developed in the context of classroom observations and interviews. Chapter 4 focuses on topics related to the profession of teachers: What self-concepts are pursued by teachers of Religious Education and/or can be reconstructed through the way they act in the classroom? How can the often critical perceptions of teachers who use digital media in religious education be put to good use in the future? The conclusion bundles the most important insights and highlights examples of further research.}, subject = {Digitalisierung}, language = {en} } @techreport{MagnusLinkerMeuthetal.2011, author = {Magnus, Tim and Linker, Ralf A. and Meuth, Sven G. and Kleinschnitz, Christoph and Korn, Thomas}, title = {Report on the 2nd scientific meeting of the "Verein zur Foerderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 29'th - Oct. 31'st, 2010}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-68789}, year = {2011}, abstract = {Summary of the scientific contributions to the NEUROWIND meeting 2010: Contributions in the fields of neuroimmunology and neurodegeneration}, subject = {Wissenschaftlicher Nachwuchs}, language = {en} } @techreport{LinkerMeuthMagnusetal.2012, author = {Linker, Ralf, A. and Meuth, Sven G. and Magnus, Tim and Korn, Thomas and Kleinschnitz, Christoph}, title = {Report on the 4'th scientific meeting of the "Verein zur F{\"o}rderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 2'nd - Nov. 4'th, 2012 [meeting report]}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-76407}, year = {2012}, abstract = {From November 2nd - 4th 2012, the 4th NEUROWIND e.V. meeting was held in Motzen, Brandenburg, Germany. Again more than 60 participants, predominantly at the doctoral student or postdoc level, gathered to share their latest findings in the fields of neurovascular research, neurodegeneration and neuroinflammation. Like in the previous years, the symposium provided an excellent platform for scientific exchange and the presentation of innovative projects in the stimulating surroundings of the Brandenburg outback. This year's keynote lecture on the pathophysiological relevance of neuronal networks was given by Christian Gerloff, Head of the Department of Neurology at the University Clinic of Hamburg-Eppendorf. Another highlight of the meeting was the awarding of the NEUROWIND e.V. prize for young scientists working in the field of experimental neurology. The award is donated by the Merck Serono GmbH, Darmstadt, Germany and is endowed with 20.000 Euro. This year the jury decided unanimously to adjudge the award to Michael Gliem from the Department of Neurology at the University Clinic of D{\"u}sseldorf (group of Sebastian Jander), Germany, for his outstanding work on different macrophage subsets in the pathogenesis of ischemic stroke published in the Annals of Neurology in 2012.}, subject = {Medizin}, language = {en} } @techreport{OPUS4-4855, title = {R{\"u}ckBLICK - Der Jahresbericht 2010 der Julius-Maximilians-Universit{\"a}t W{\"u}rzburg}, volume = {2010}, organization = {Julius-Maximilians-Universit{\"a}t W{\"u}rzburg}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-57158}, year = {2011}, abstract = {Die Entwicklung der Universit{\"a}t W{\"u}rzburg im Jahr 2010.}, subject = {W{\"u}rzburg}, language = {de} } @techreport{MaennelBorschinskyKayaletal.2024, author = {M{\"a}nnel, Jonathan and Borschinsky, Erik and Kayal, Hakan and Neumann, Tobias and Riegler, Clemens}, title = {SATEX: Extraterrestrik mit Kleinsatelliten - Kurzbericht}, doi = {10.25972/OPUS-36325}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-363256}, pages = {42}, year = {2024}, abstract = {Dieser Kurzbericht beleuchtet die Einsatzm{\"o}glichkeiten von Kleinsatelliten in der extraterrestrischen Forschung und zeigt auf welche technologischen Herausforderungen sich bei ihrem Einsatz ergeben. Die pr{\"a}sentierten Ergebnisse sind Teil der SATEX Untersuchung (FKZ 50OO2222). In diesem Dokument werden zun{\"a}chst die allgemeinen Einsatzm{\"o}glichkeiten von Kleinsatelliten in der Extraterrestrik anhand ausgew{\"a}hlter Beispielmissionen beleuchtet. Daraufhin erfolgt die Er{\"o}rterung spezifischer technischer Herausforderungen und Umweltbedingungen bei cislunaren und interplanetaren Kleinsatellitenmissionen, gefolgt von einer kurzen Pr{\"a}sentation von Nutzerw{\"u}nsche aus Deutschland f{\"u}r Missionen zur Erforschung des Weltraums. Zum Abschluss werden zehn konkrete, im Rahmen der Untersuchung ermittelte, Missionsideen vorgestellt und bewertet. Schließlich erfolgt die Zusammenfassung der wichtigsten Erkenntnisse und Empfehlungen.}, subject = {Extraterrestrische Forschung}, language = {de} }