@article{JockelSchneiderHarksHaubitzetal.2014,
  author    = {Jockel-Schneider, Yvonne and Harks, Inga and Haubitz, Imme and Fickl, Stefan and Eigenthaler, Martin and Schlagenhauf, Ulrich and Baulmann, Johannes},
  title     = {Arterial Stiffness and Pulse Wave Reflection Are Increased in Patients Suffering from Severe Periodontitis},
  series = {PLOS ONE},
  volume    = {9},
  journal   = {PLOS ONE},
  number    = {8},
  issn      = {1932-6203},
  doi       = {10.1371/journalone.0103449},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-119459},
  pages     = {e103449},
  year      = {2014},
  abstract  = {Aim: This single blind cross-sectional study compared the vascular health of subjects suffering from severe chronic periodontitis, severe aggressive periodontitis and periodontal healthy controls by evaluating pulse wave velocity (PWV), augmentation index (AIx) and pulse pressure amplification (PPA). Material and Methods: In a total of 158 subjects, 92 suffering from severe periodontitis and 66 matched periodontal healthy controls, PWV, AIx, central and peripheral blood pressure were recorded using an oscillometric device (Arteriograph). Results: Subjects suffering from severe chronic or aggressive periodontitis exhibited significantly higher PWV (p = 0.00004), higher AIx (p = 0.0049) and lower PPA (p = 0.028) than matched periodontal healthy controls. Conclusions: The results of this study confirm the association between periodontal inflammation and increased cardiovascular risk shown by impaired vascular health in case of severe periodontitis. As impaired vascular health is a common finding in patients suffering from severe periodontal disease a concomitant routine cardiovascular evaluation may be advised.},
  language  = {en}
}
@article{JockelSchneiderStoelzelHessetal.2022,
  author    = {Jockel-Schneider, Yvonne and Stoelzel, Peggy and Hess, Jeanine and Haubitz, Imme and Fickl, Stefan and Schlagenhauf, Ulrich},
  title     = {Impact of a specific collagen peptide food supplement on periodontal inflammation in aftercare patients — a randomised controlled trial},
  series = {Nutrients},
  volume    = {14},
  journal   = {Nutrients},
  number    = {21},
  issn      = {2072-6643},
  doi       = {10.3390/nu14214473},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-290471},
  year      = {2022},
  abstract  = {Background: This controlled clinical trial evaluated the impact of a specific collagen peptide food supplement on parameters of periodontal inflammation in aftercare patients. Methods: A total of 39 study patients were enrolled. At baseline, bleeding on probing (BoP; primary outcome), gingival index (GI), plaque control record (PCR), recession (REC) and probing pocket depth (PPD) for the calculation of the periodontal inflamed surface area (PISA) were documented. After subsequent professional mechanical plaque removal (PMPR), participants were randomly provided with a supply of sachets containing either a specific collagen peptide preparation (test group; n = 20) or a placebo (placebo group; n = 19) to be consumed dissolved in liquid once daily until reevaluation at day 90. Results: PMPR supplemented with the consumption of the specific collagen peptides resulted in a significantly lower mean percentage of persisting BoP-positive sites than PMPR plus placebo (test: 10.4\% baseline vs. 3.0\% reevaluation; placebo: 14.2\% baseline vs. 9.4\% reevaluation; effect size: 0.86). Mean PISA and GI values were also reduced compared to baseline, with a significant difference in favor of the test group (PISA test: 170.6 mm\(^2\) baseline vs. 53.7 mm\(^2\) reevaluation; PISA placebo: 229.4 mm\(^2\) baseline vs. 184.3 mm\(^2\) reevaluation; GI test: 0.5 baseline vs. 0.1 reevaluation; GI placebo: 0.4 baseline vs. 0.3 reevaluation). PCR was also significantly decreased in both experimental groups at revaluation, but the difference between the groups did not reach the level of significance. Conclusions: The supplementary intake of specific collagen peptides may further enhance the anti-inflammatory effect of PMPR in periodontal recall patients.},
  language  = {en}
}