@article{TomasekOtt2016, author = {Tomasek, Stefan and Ott, Christine}, title = {Nils Mohl und Hartmann von Aue. Zur intertextuellen Verweisstruktur in Stadtrandritter und ihrem didaktischen Potential f{\"u}r den Deutschunterricht.}, series = {Literatur im Unterricht - Texte der Gegenwartsliteratur f{\"u}r die Schule}, journal = {Literatur im Unterricht - Texte der Gegenwartsliteratur f{\"u}r die Schule}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-210590}, pages = {267-286}, year = {2016}, abstract = {Kein Abstract verf{\"u}gbar.}, language = {de} } @incollection{StaffeldtOtt2014, author = {Staffeldt, Sven and Ott, Christine}, title = {Sprechen als kommunikative Ressource. Was die linguistische Pragmatik f{\"u}r den Kompetenzbereich ‚Sprechen' zu bieten hat}, series = {Deutschunterricht am Gymnasium. Was kann die Sprachwissenschaft leisten?}, booktitle = {Deutschunterricht am Gymnasium. Was kann die Sprachwissenschaft leisten?}, publisher = {Schneider Verlag Hohengehren}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-210649}, publisher = {Universit{\"a}t W{\"u}rzburg}, pages = {66-83}, year = {2014}, abstract = {Kein Abstract verf{\"u}gbar}, language = {de} } @phdthesis{Ott2013, author = {Ott, Christine Kornelia}, title = {Diverse Aspects of the Sorting and Assembly Machinery in Human Mitochondria}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-85462}, school = {Universit{\"a}t W{\"u}rzburg}, year = {2013}, abstract = {Mitochondria are organelles of endosymbiotic origin, which play many important roles in eukaryotic cells. Mitochondria are surrounded by two membranes and, considering that most of the mitochondrial proteins are produced in the cytosol, possess import machineries, which transport mitochondria-targeted proteins to their designated location. A special class of outer mitochondrial membrane (OMM) proteins, the β-barrel proteins, require the sorting and assembly machinery (SAM) for their OMM integration. Both mitochondrial β-barrel proteins and the central component of the SAM complex, Sam50, have homologs in gram-negative bacteria. In yeast mitochondria, bacterial β-barrel proteins can be imported and assembled into the OMM. Our group demonstrated that this, however, is not the case for human mitochondria, which import only neisserial β barrel proteins, but not those of Escherichia coli and Salmonella enterica. As a part of this study, I could demonstrate that β-barrel proteins such as Omp85 and PorB of different Neisseria species are targeted to human mitochondria. Interestingly, only proteins belonging to the neisserial Omp85 family were integrated into the OMM, whereas PorB was imported into mitochondria but not assembled. By exchanging parts of homologous neisserial Omp85 and E. coli BamA and, similarly, of neisserial PorB and E. coli OmpC, it could be demonstrated in this work that the mitochondrial import signal of bacterial β barrel proteins cannot be limited to one short linear sequence, but rather secondary structure and protein charge seem to play an important role, as well as specific residues in the last β-strand of Omp85. Omp85 possesses five conserved POTRA domains in its amino-terminal part. This work additionally demonstrated that in human mitochondria, at least two POTRA domains of Omp85 are necessary for membrane integration and functionality of Omp85. In the second part of this work, the influence of Sam50 on the mitochondrial cristae structure was investigated. This work contributed to a study performed by our group in which it was confirmed that Sam50 is present in a high molecular weight complex together with mitofilin, CHCHD3, CHCHD6, DnaJC11, metaxin 1 and metaxin 2. This connection between the inner and outer mitochondrial membrane was shown to be crucial for the maintenance of the mitochondrial cristae structure. In addition, a role of Sam50 in respiratory complex assembly, suggested by a SILAC experiment conducted in our group, could be confirmed by in vitro import studies. An influence of Sam50 not only on respiratory complexes but also on the recently described respiratory complex assembly factor TTC19 was demonstrated. It was shown that TTC19 not only plays a role in complex III assembly as published, but also influences the assembly of respiratory complex IV. Thus, in this part of the work a connection between the OMM protein Sam50 and maintenance of cristae structure, respiratory complex assembly and an assembly factor could be established.}, subject = {Mitochondrien}, language = {en} } @incollection{OttKiesendahl2019, author = {Ott, Christine and Kiesendahl, Jana}, title = {Ratgeber und RAT GEBEN. Textlinguistische Reflexionen zur Identifizierung, Typologisierung und pragmatisch-stilistischen Analyse von Ratgebern.}, series = {Ratgeberforschung in der Erziehungswissenschaft. Grundlagen - Theorien - Reflexionen.}, booktitle = {Ratgeberforschung in der Erziehungswissenschaft. Grundlagen - Theorien - Reflexionen.}, publisher = {Verlag Julius Klinkhardt}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-210580}, publisher = {Universit{\"a}t W{\"u}rzburg}, pages = {65-94}, year = {2019}, abstract = {Kein Abstract verf{\"u}gbar.}, language = {de} } @article{OttDorschFraunholzetal.2015, author = {Ott, Christine and Dorsch, Eva and Fraunholz, Martin and Straub, Sebastian and Kozjak-Pavlovic, Vera}, title = {Detailed Analysis of the Human Mitochondrial Contact Site Complex Indicate a Hierarchy of Subunits}, series = {PLoS One}, volume = {10}, journal = {PLoS One}, number = {3}, doi = {10.1371/journal.pone.0120213}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-125347}, pages = {e0120213}, year = {2015}, abstract = {Mitochondrial inner membrane folds into cristae, which significantly increase its surface and are important for mitochondrial function. The stability of cristae depends on the mitochondrial contact site (MICOS) complex. In human mitochondria, the inner membrane MICOS complex interacts with the outer membrane sorting and assembly machinery (SAM) complex, to form the mitochondrial intermembrane space bridging complex (MIB). We have created knockdown cell lines of most of the MICOS and MIB components and have used them to study the importance of the individual subunits for the cristae formation and complex stability. We show that the most important subunits of the MIB complex in human mitochondria are Mic60/Mitofilin, Mic19/CHCHD3 and an outer membrane component Sam50. We provide additional proof that ApoO indeed is a subunit of the MICOS and MIB complexes and propose the name Mic23 for this protein. According to our results, Mic25/CHCHD6, Mic27/ApoOL and Mic23/ApoO appear to be periphery subunits of the MICOS complex, because their depletion does not affect cristae morphology or stability of other components.}, language = {en} } @incollection{Ott2016, author = {Ott, Christine}, title = {Zur Ver- und Entschr{\"a}nkung von Schulbucharbeit und Schulbuchzulassung. Theoretische Grundlegung und historische Skizze.}, series = {Schulb{\"u}cher auf dem Pr{\"u}fstand}, booktitle = {Schulb{\"u}cher auf dem Pr{\"u}fstand}, publisher = {Verlag Julius Klinkhardt}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-203986}, publisher = {Universit{\"a}t W{\"u}rzburg}, pages = {31-50}, year = {2016}, abstract = {Kein Abstract verf{\"u}gbar.}, language = {de} } @incollection{Ott2017, author = {Ott, Christine}, title = {Geschlechterforschung zu Schulb{\"u}chern gestern und heute. Forschungsparadigmen und Methodik.}, series = {Heterogenit{\"a}t und Bildungsmedien / Heterogeneity and Educational Media}, booktitle = {Heterogenit{\"a}t und Bildungsmedien / Heterogeneity and Educational Media}, publisher = {Verlag Julius Kinkhardt}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-203975}, publisher = {Universit{\"a}t W{\"u}rzburg}, pages = {279-290}, year = {2017}, abstract = {Kein Abstract verf{\"u}gbar.}, language = {de} } @incollection{Ott2020, author = {Ott, Christine}, title = {Literatur und Vermittlung - Anmerkungen zu deren Verh{\"a}ltnis}, series = {KONTROVERS: Literaturdidaktik meets Literaturwissenschaft}, booktitle = {KONTROVERS: Literaturdidaktik meets Literaturwissenschaft}, publisher = {WTV}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-210601}, publisher = {Universit{\"a}t W{\"u}rzburg}, pages = {303-322}, year = {2020}, abstract = {Kein Abstract verf{\"u}gbar.}, language = {de} } @article{Ott2017, author = {Ott, Christine}, title = {Literarisches Dorfleben in Maienfeld oder Wie Heidi lebte.}, series = {kjl\&m - Kinder-/Jugendliteratur und Medien in Forschung, Literatur und Bibliothek}, volume = {69}, journal = {kjl\&m - Kinder-/Jugendliteratur und Medien in Forschung, Literatur und Bibliothek}, number = {3}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-210610}, pages = {14-22}, year = {2017}, abstract = {Kein Abstract verf{\"u}gbar.}, language = {de} } @incollection{Ott2016, author = {Ott, Christine}, title = {40 Jahre Geschlechterforschung zu Rechen- und Mathematikb{\"u}chern. Forschungsparadigmen und Methodik im Wandel}, series = {Mathematik und Gender: Frauen in der Mathematikgeschichte - M{\"a}dchen und Mathematikunterricht heute}, booktitle = {Mathematik und Gender: Frauen in der Mathematikgeschichte - M{\"a}dchen und Mathematikunterricht heute}, publisher = {Franzbecker}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-210629}, publisher = {Universit{\"a}t W{\"u}rzburg}, pages = {65-72}, year = {2016}, abstract = {Kein Abstract verf{\"u}gbar.}, language = {de} }