@article{ThomasMyers‐SmithBjorkmanetal.2019, author = {Thomas, H. J. D. and Myers-Smith, I. H. and Bjorkman, A. D. and Elmendorf, S. C. and Blok, D. and Cornelissen, J. H. C. and Forbes, B. C. and Hollister, R. D. and Normand, S. and Prev{\´e}y, J. S. and Rixen, C. and Schaepman-Strub, G. and Wilmking, M. and Wipf, S. and Cornwell, W. K. and Kattge, J. and Goetz, S. J. and Guay, K. C. and Alatalo, J. M. and Anadon-Rosell, A. and Angers-Blondin, S. and Berner, L. T. and Bj{\"o}rk, R. G. and Buchwal, A. and Buras, A. and Carbognani, M. and Christie, K. and Siegwart Collier, L. and Cooper, E. J. and Eskelinen, A. and Frei, E. R. and Grau, O. and Grogan, P. and Hallinger, M. and Heijmans, M. M. P. D. and Hermanutz, L. and Hudson, J. M. G. and H{\"u}lber, K. and Iturrate-Garcia, M. and Iversen, C. M. and Jaroszynska, F. and Johnstone, J. F. and Kaarlej{\"a}rvi, E. and Kulonen, A. and Lamarque, L. J. and L{\´e}vesque, E. and Little, C. J. and Michelsen, A. and Milbau, A. and Nabe-Nielsen, J. and Nielsen, S. S. and Ninot, J. M. and Oberbauer, S. F. and Olofsson, J. and Onipchenko, V. G. and Petraglia, A. and Rumpf, S. B. and Semenchuk, P. R. and Soudzilovskaia, N. A. and Spasojevic, M. J. and Speed, J. D. M. and Tape, K. D. and te Beest, M. and Tomaselli, M. and Trant, A. and Treier, U. A. and Venn, S. and Vowles, T. and Weijers, S. and Zamin, T. and Atkin, O. K. and Bahn, M. and Blonder, B. and Campetella, G. and Cerabolini, B. E. L. and Chapin III, F. S. and Dainese, M. and de Vries, F. T. and D{\´i}az, S. and Green, W. and Jackson, R. B. and Manning, P. and Niinemets, {\"U}. and Ozinga, W. A. and Pe{\~n}uelas, J. and Reich, P. B. and Schamp, B. and Sheremetev, S. and van Bodegom, P. M.}, title = {Traditional plant functional groups explain variation in economic but not size-related traits across the tundra biome}, series = {Global Ecology and Biogeography}, volume = {28}, journal = {Global Ecology and Biogeography}, doi = {10.1111/geb.12783}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-241310}, pages = {78-95}, year = {2019}, abstract = {Aim Plant functional groups are widely used in community ecology and earth system modelling to describe trait variation within and across plant communities. However, this approach rests on the assumption that functional groups explain a large proportion of trait variation among species. We test whether four commonly used plant functional groups represent variation in six ecologically important plant traits. Location Tundra biome. Time period Data collected between 1964 and 2016. Major taxa studied 295 tundra vascular plant species. Methods We compiled a database of six plant traits (plant height, leaf area, specific leaf area, leaf dry matter content, leaf nitrogen, seed mass) for tundra species. We examined the variation in species-level trait expression explained by four traditional functional groups (evergreen shrubs, deciduous shrubs, graminoids, forbs), and whether variation explained was dependent upon the traits included in analysis. We further compared the explanatory power and species composition of functional groups to alternative classifications generated using post hoc clustering of species-level traits. Results Traditional functional groups explained significant differences in trait expression, particularly amongst traits associated with resource economics, which were consistent across sites and at the biome scale. However, functional groups explained 19\% of overall trait variation and poorly represented differences in traits associated with plant size. Post hoc classification of species did not correspond well with traditional functional groups, and explained twice as much variation in species-level trait expression. Main conclusions Traditional functional groups only coarsely represent variation in well-measured traits within tundra plant communities, and better explain resource economic traits than size-related traits. We recommend caution when using functional group approaches to predict tundra vegetation change, or ecosystem functions relating to plant size, such as albedo or carbon storage. We argue that alternative classifications or direct use of specific plant traits could provide new insights for ecological prediction and modelling.}, language = {en} } @article{BanalesCardinaleCarpinoetal.2016, author = {Banales, Jesus M. and Cardinale, Vincenzo and Carpino, Guido and Marzioni, Marco and Andersen, Jesper B. and Invernizzi, Pietro and Lind, Guro E. and Folseraas, Trine and Forbes, Stuart J. and Fouassier, Laura and Geier, Andreas and Calvisi, Diego F. and Mertens, Joachim C. and Trauner, Michael and Benedetti, Antonio and Maroni, Luca and Vaquero, Javier and Macias, Rocio I. R. and Raggi, Chiara and Perugorria, Maria J. and Gaudio, Eugenio and Boberg, Kirsten M. and Marin, Jose J. G. and Alvaro, Domenico}, title = {Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)}, series = {Nature Reviews Gastroenterology \& Hepatology}, volume = {13}, journal = {Nature Reviews Gastroenterology \& Hepatology}, number = {5}, doi = {10.1038/nrgastro.2016.51}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-189077}, pages = {261-280}, year = {2016}, abstract = {Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of biliary tract differentiation. CCA is the second most common primary liver tumour and the incidence is increasing worldwide. CCA has high mortality owing to its aggressiveness, late diagnosis and refractory nature. In May 2015, the "European Network for the Study of Cholangiocarcinoma" (ENS-CCA: www.enscca.org or www.cholangiocarcinoma.eu) was created to promote and boost international research collaboration on the study of CCA at basic, translational and clinical level. In this Consensus Statement, we aim to provide valuable information on classifications, pathological features, risk factors, cells of origin, genetic and epigenetic modifications and current therapies available for this cancer. Moreover, future directions on basic and clinical investigations and plans for the ENS-CCA are highlighted.}, language = {en} }