@techreport{JonjicKazekaMettenetal.2016,
  type      = {Working Paper},
  author    = {Jonjic, Andrea and Kazeka, Papy Manzanza and Metten, Daniel and Tietgen, Flora},
  title     = {Die Transnationale Zivilgesellschaft - Hoffnungstr{\"a}ger in der Global Governance?},
  doi       = {10.25972/OPUS-13076},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-130762},
  pages     = {51},
  year      = {2016},
  abstract  = {Angesichts weltweiter Krisen und Konflikte ist eine st{\"a}rkere Einbindung der Transnationalen Zivilgesellschaft notwendiger denn je. Ihr Engagement f{\"u}r mehr Demokratie, Transparenz und Gerechtigkeit brachte ihr den Status eines Hoffnungstr{\"a}gers in der Global Governance ein - vor allem in den 1990er Jahren, als der Fokus zunehmend auf nichtstaatliche Akteure gerichtet wurde. Mit den globalen Herausforderungen der Jahrtausendwende r{\"u}ckten jedoch Nationalstaaten wieder in den Mittelpunkt, und es stellt sich die Frage, inwiefern die Akteure der Transnationalen Zivilgesellschaft angesichts dieser ver{\"a}nderten Konstellationen noch als Hoffnungstr{\"a}ger bei der Bew{\"a}ltigung weltweiter Krisen gelten k{\"o}nnen. Dieser Beitrag argumentiert, dass trotz wesentlicher Schwachstellen wie des Legitimit{\"a}tsdefizits, der vielschichtigen Abh{\"a}ngigkeiten und der Ungleichheit im Nord-S{\"u}d-Gef{\"a}lle die Transnationale Zivilgesellschaft eine essentielle Rolle in der Global Governance wahrnimmt. Sie f{\"u}hrt zu mehr Effizienz in Governance-Strukturen, f{\"o}rdert demokratische Prozesse, schafft mehr Transparenz in internationalen Verhandlungen und leistet somit einen Beitrag zu einer gerechteren Welt - ein Hoffnungstr{\"a}ger also im globalen M{\"a}chtekonzert.},
  subject      = {B{\"u}rgerliche Gesellschaft},
  language  = {de}
}
@article{LodhaMuchsinJuergesetal.2023,
  author    = {Lodha, Manivel and Muchsin, Ihsan and J{\"u}rges, Christopher and Juranic Lisnic, Vanda and L'Hernault, Anne and Rutkowski, Andrzej J. and Prusty, Bhupesh K. and Grothey, Arnhild and Milic, Andrea and Hennig, Thomas and Jonjic, Stipan and Friedel, Caroline C. and Erhard, Florian and D{\"o}lken, Lars},
  title     = {Decoding murine cytomegalovirus},
  series = {PLOS Pathogens},
  volume    = {19},
  journal   = {PLOS Pathogens},
  number    = {5},
  issn      = {1553-7374},
  doi       = {10.1371/journal.ppat.1010992},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-350480},
  year      = {2023},
  abstract  = {The genomes of both human cytomegalovirus (HCMV) and murine cytomegalovirus (MCMV) were first sequenced over 20 years ago. Similar to HCMV, the MCMV genome had initially been proposed to harbor ≈170 open reading frames (ORFs). More recently, omics approaches revealed HCMV gene expression to be substantially more complex comprising several hundred viral ORFs. Here, we provide a state-of-the art reannotation of lytic MCMV gene expression based on integrative analysis of a large set of omics data. Our data reveal 365 viral transcription start sites (TiSS) that give rise to 380 and 454 viral transcripts and ORFs, respectively. The latter include 200 small ORFs, some of which represented the most highly expressed viral gene products. By combining TiSS profiling with metabolic RNA labelling and chemical nucleotide conversion sequencing (dSLAM-seq), we provide a detailed picture of the expression kinetics of viral transcription. This not only resulted in the identification of a novel MCMV immediate early transcript encoding the m166.5 ORF, which we termed ie4, but also revealed a group of well-expressed viral transcripts that are induced later than canonical true late genes and contain an initiator element (Inr) but no TATA- or TATT-box in their core promoters. We show that viral upstream ORFs (uORFs) tune gene expression of longer viral ORFs expressed in cis at translational level. Finally, we identify a truncated isoform of the viral NK-cell immune evasin m145 arising from a viral TiSS downstream of the canonical m145 mRNA. Despite being ≈5-fold more abundantly expressed than the canonical m145 protein it was not required for downregulating the NK cell ligand, MULT-I. In summary, our work will pave the way for future mechanistic studies on previously unknown cytomegalovirus gene products in an important virus animal model.},
  language  = {en}
}