@article{SchartlSchartlAnders1982, author = {Schartl, A. and Schartl, Manfred and Anders, F.}, title = {Promotion and regression of neoplasia by testosterone-promoted cell differentiation in Xiphophorus and Girardinus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86684}, year = {1982}, abstract = {No abstract available.}, subject = {Schwertk{\"a}rpfling}, language = {en} } @inproceedings{SchartlSchartlAnders1981, author = {Schartl, A. and Schartl, Manfred and Anders, F.}, title = {Phenotypic conversion of malignant melanoma to benign melanoma and vice versa in Xiphophorus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86662}, year = {1981}, abstract = {No abstract available.}, subject = {Schwertk{\"a}rpfling}, language = {en} } @article{SchartlBarnekowBaueretal.1982, author = {Schartl, Manfred and Barnekow, A. and Bauer, H. and Anders, F.}, title = {Correlations of inheritance and expression between a tumor gene and the cellular homolog of the Rous sarcoma virus-transforming gene in Xiphophorus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61937}, year = {1982}, abstract = {No abstract available}, subject = {Physiologische Chemie}, language = {en} } @article{BarnekowSchartlAndersetal.1982, author = {Barnekow, A. and Schartl, Manfred and Anders, F. and Bauer, H.}, title = {Identification of a fish protein associated with a kinase activity and related to the Rous sarcoma virus transforming protein}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-61946}, year = {1982}, abstract = {No abstract available}, subject = {Physiologische Chemie}, language = {en} } @article{AndersSchartlBarnekowetal.1984, author = {Anders, F. and Schartl., Manfred and Barnekow, A. and Anders, A.}, title = {Xiphophorus as an in vivo model for studies on normal and defective control of oncogenes}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-80721}, year = {1984}, abstract = {The Xiphophorus tumor system has provided the opportunity to reduce the enormous complexity of cancer etiology to a few biological elements basically involved in neoplasia. The development of a tumor requires an oncogene which, after impairment, deletion, or elimination of its regulatory genes is permitted to mediate neoplastic transformation. Emphasis is being placed today in cancer research on the actual oncogenes themselves, but, in our opinion, the most important genes involved in neoplasia are these regulatory genes. However, although detected by c1assical genetics in the Xiphophorus system, th ese genes are not at present open to a more fin ely detailed molecular biological analysis. Their actual mode of action is therefore still far from being understood.}, subject = {Xiphophorus}, language = {en} } @inproceedings{PeterSchartlAndersetal.1985, author = {Peter, R. U. and Schartl, Manfred and Anders, F. and Duncker, H.-R.}, title = {Pigment pattern formation during embryogenesis in Xiphophorus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-69370}, year = {1985}, abstract = {No abstract available.}, subject = {Schwertk{\"a}rpfling}, language = {en} } @article{AndersSchartlBarnekowetal.1985, author = {Anders, F. and Schartl, Manfred and Barnekow, A. and Schmidt, C. R. and Luke, W. and Jaenel-Dess, G. and Anders, A.}, title = {The genes that carcinogens act upon}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72704}, year = {1985}, abstract = {No abstract available.}, subject = {Onkogen}, language = {en} } @inproceedings{AndersSchollSchartl1981, author = {Anders, F. and Scholl, E. and Schartl, Manfred}, title = {Environmental and hereditary factors in the causation of neoplasia, based on studies of the Xiphophorus fish melanoma system}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86402}, year = {1981}, abstract = {Neoplasia in Xiphophorus can be classified into: a) a Jarge group triggered by carcinogens; b) a large group triggered by promoters; and c) a small group that develops "spontaneously" according to Mendelian Jaw. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Interpopulational arid interracial hybridization is the most effective process that Ieads to disintegration of the protective gene systems. Environmental factors may complete disintegration in somatic cells and thus may trigger neoplasia. The applications of the findings on Xiphophorus to humans are discussed.}, subject = {Schwertk{\"a}rpfling}, language = {en} } @inproceedings{AndersSchartlScholl1981, author = {Anders, F. and Schartl, Manfred and Scholl, E.}, title = {Evaluation of environmental and hereditary factors in carcinogenesis, based on studies in Xiphophorus}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72741}, year = {1981}, abstract = {Neoplasia in Xiphophorus can be classified into a) a large group that is triggered by carcinogens; b) a large group triggered by promoters; c) a small group that develops "spontaneously" following interpopulational and interracial hybridizations; and d) a small group that develops "spontaneously" following germ line mutation. The process leading to susceptibility for neoplasia is represented by the disintegration of gene systems that normally protect the fish from neoplasia. Hybridization is the most effective process that leads to disintegration of the protection gene systems. Environmental factors may complete disintegration and thus may trigger neoplasia. It is discussed whether the findings on Xiphophorus may also apply to humans.}, subject = {Schwertk{\"a}rpfling}, language = {en} } @incollection{AndersSchollSchartl1979, author = {Anders, F. and Scholl, E. and Schartl, Manfred}, title = {Xiphophorus als Modell in der Krebsforschung}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-72752}, publisher = {Universit{\"a}t W{\"u}rzburg}, year = {1979}, abstract = {No abstract available.}, subject = {Schwertk{\"a}rpfling}, language = {de} }