@article{FalkUlrichsMuellerRuchholtz1987, author = {Falk, W. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {15-Deoxyspergualin (a new guanidine-like drug) blocks T lymphocyte proliferation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45215}, year = {1987}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @inproceedings{UlrichsEulerMuellerRuchholtz1991, author = {Ulrichs, Karin and Euler, HH and M{\"u}ller-Ruchholtz, W.}, title = {A Clinically Successful Protocol to Suppress Autoantibody Production in SLE Patients Is Analyzed For Its Efficacy To Inhibit Natural Xenophile Antibodies (NXA)}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45693}, year = {1991}, abstract = {No abstract available}, language = {en} } @article{UlrichsWinotoMorbachHeringetal.1990, author = {Ulrichs, Karin and Winoto-Morbach, S. and Hering, B. and M{\"u}ller-Ruchholtz, W.}, title = {A Useful Biotechnological Approach to Solve the Problem of Graft Purity in Human Pancreatic Islet Transplantation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45619}, year = {1990}, abstract = {No abstract available}, subject = {Chirurgie}, language = {en} } @article{LausUlrichsMuellerRuchholtz1988, author = {Laus, R. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Carbohydrate-specific human heterophile antibodies in normal human sera that react with xenogeneic cells}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-78271}, year = {1988}, abstract = {Human heterophile antibodies (HHA) that are present in normal human sera (NHS)play an important role in hyperacute xenograft rejection. The aim of this study was to analyze the occurrence, mode of action and molecular specificity of HHA in NHS that are directed against xenogeneic Iymphocytes (isolated from mouse, rat, guinea pig, rabbit, cattle and pig) and isolated rat pancreatic islets. All sera contained variable amounts of HHA that killed the target cells via the classical complement pathway. The cytotoxic activity of these HHA was specifically inhibited by certain carbohydrates (a-D-melibiose, ß-Iactose, ß-gentiobiose, ß-cellobiose, D-mannose, N-acetyl-ß-D-mannosamine and a-D-rhamnose) and by rat IgM. By means of affinity chromatography with immobilized inhibitors we obtained an antibody preparation of mainly IgG type from NHS (up to 3.5 mg/IO ml serum) that reacted strongly with rat lymphocytes and isolated rat pancreatic islets. Though thus far residual xenospecific antibody activity has remained in the sera even after multiple affinity chromatography, these data suggest that specific elimination of HHA is feasible and that it may be thus possible to overcome a major obstacle to xenotransplantation.}, subject = {Immunobiologie}, language = {de} } @article{UlrichsEcksteinKorsgrenetal.1994, author = {Ulrichs, Karin and Eckstein, V. and Korsgren, O. and Tibell, A. and Groth, C. G. and M{\"u}ller-Ruchholtz, W.}, title = {Characterization of natural and induced human xenophile antibodies before and after transplantation of the fetal porcine endocrine pancreas}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86985}, year = {1994}, abstract = {No abstract available.}, subject = {Bauspeicheldr{\"u}se}, language = {de} } @article{DeltzMuellerHermelinkUlrichsetal.1981, author = {Deltz, E. and M{\"u}ller-Hermelink, HK and Ulrichs, Karin and Thiede, A. and M{\"u}ller-Ruchholtz, W.}, title = {Development of graft-versus-host reaction in various target organs after small intestine transplantation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45459}, year = {1981}, abstract = {The GVHRIL foHowing transplantation of small intestine are different from those found after bone marrow transplantation or spleen cell injections in that they show a remarka ble, significant prevalence of lesions within the intestinal mucosa. These findings are consistent with the observation that jntestinal lymphocytes newly formed in mesenteric lymph nodes predominantly home in on the intestine again.\& The degree of histologic alteration within different tissues indicates that the graft and the host may survive the lesions of the lymphatic tissues, whereas the severe intestinal lesions following GVHR may easily cause death of the recipient. With regard to clinical sman bowel transplantation two statements can be made: (l) GVHRIL play a significant role in small bowel trans~ plantation. (2) To minimize their biologic importance, a selective elimination of the graft's Jymph nodes by irradiation or surgical resection should be considered in view of the remarkable difference between GVHRIL in lymph nodes and in the graft's intestinal wall itself.}, subject = {Chirurgie}, language = {en} } @article{UlrichsEcksteinHeiseretal.1992, author = {Ulrichs, Karin and Eckstein, V. and Heiser, A. and M{\"u}ller-Ruchholtz, W.}, title = {Die zellvermittelte Immunantwort des menschlichen Transplantat Empf{\"a}ngers gegen xenogenes Antigen (Schwein) ist abh{\"a}ngig vom Spenderkompartiment.}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-86978}, year = {1992}, abstract = {No abstract available.}, subject = {Transplantation}, language = {de} } @inproceedings{WangUlrichsMuellerRuchholtz1993, author = {Wang, HY and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Down-Regulation of Xenophile Antibodies by Specific Immunosuppressive Protocols to Facilitate Xenogeneic Organ Transplantation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45669}, year = {1993}, abstract = {No abstract available}, subject = {Immunbiologie}, language = {en} } @inproceedings{HeiserUlrichsMuellerRuchholtz1994, author = {Heiser, A. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Enzyme Activities in Commercial Collagenase Preparations and Their Kinetics During Islet Isolation Procedure}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45633}, year = {1994}, abstract = {No abstract available}, subject = {Transplantation}, language = {en} } @inproceedings{HeiserUlrichsMuellerRuchholtz1994, author = {Heiser, A. and Ulrichs, Karin and M{\"u}ller-Ruchholtz, W.}, title = {Enzyme Kinetics of Commercial Collagenases and their Influence on Porcine Islet Isolation}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45488}, year = {1994}, abstract = {No abstract available}, subject = {Heterotransplantation}, language = {en} }