@article{FathyDarwishAbdelhamidetal.2022, author = {Fathy, Moustafa and Darwish, Mostafa A. and Abdelhamid, Al-Shaimaa M. and Alrashedy, Gehad M. and Othman, Othman Ali and Naseem, Muhammad and Dandekar, Thomas and Othman, Eman M.}, title = {Kinetin ameliorates cisplatin-induced hepatotoxicity and lymphotoxicity via attenuating oxidative damage, cell apoptosis and inflammation in rats}, series = {Biomedicines}, volume = {10}, journal = {Biomedicines}, number = {7}, issn = {2227-9059}, doi = {10.3390/biomedicines10071620}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-281686}, year = {2022}, abstract = {Though several previous studies reported the in vitro and in vivo antioxidant effect of kinetin (Kn), details on its action in cisplatin-induced toxicity are still scarce. In this study we evaluated, for the first time, the effects of kinetin in cisplatin (cp)- induced liver and lymphocyte toxicity in rats. Wistar male albino rats were divided into nine groups: (i) the control (C), (ii) groups 2,3 and 4, which received 0.25, 0.5 and 1 mg/kg kinetin for 10 days; (iii) the cisplatin (cp) group, which received a single intraperitoneal injection of CP (7.0 mg/kg); and (iv) groups 6, 7, 8 and 9, which received, for 10 days, 0.25, 0.5 and 1 mg/kg kinetin or 200 mg/kg vitamin C, respectively, and Cp on the fourth day. CP-injected rats showed a significant impairment in biochemical, oxidative stress and inflammatory parameters in hepatic tissue and lymphocytes. PCR showed a profound increase in caspase-3, and a significant decline in AKT gene expression. Intriguingly, Kn treatment restored the biochemical, redox status and inflammatory parameters. Hepatic AKT and caspase-3 expression as well as CD95 levels in lymphocytes were also restored. In conclusion, Kn mitigated oxidative imbalance, inflammation and apoptosis in CP-induced liver and lymphocyte toxicity; therefore, it can be considered as a promising therapy.}, language = {en} } @techreport{LohRaffeckGeissleretal.2023, type = {Working Paper}, author = {Loh, Frank and Raffeck, Simon and Geißler, Stefan and Hoßfeld, Tobias}, title = {Paving the Way for an Energy Efficient and Sustainable Future Internet of Things}, series = {KuVS Fachgespr{\"a}ch - W{\"u}rzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS'23)}, journal = {KuVS Fachgespr{\"a}ch - W{\"u}rzburg Workshop on Modeling, Analysis and Simulation of Next-Generation Communication Networks 2023 (WueWoWAS'23)}, doi = {10.25972/OPUS-32216}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-322161}, pages = {4}, year = {2023}, abstract = {In this work, we describe the network from data collection to data processing and storage as a system based on different layers. We outline the different layers and highlight major tasks and dependencies with regard to energy consumption and energy efficiency. With this view, we can outwork challenges and questions a future system architect must answer to provide a more sustainable, green, resource friendly, and energy efficient application or system. Therefore, all system layers must be considered individually but also altogether for future IoT solutions. This requires, in particular, novel sustainability metrics in addition to current Quality of Service and Quality of Experience metrics to provide a high power, user satisfying, and sustainable network.}, language = {en} } @article{SteiningerAbelZiegleretal.2023, author = {Steininger, Michael and Abel, Daniel and Ziegler, Katrin and Krause, Anna and Paeth, Heiko and Hotho, Andreas}, title = {ConvMOS: climate model output statistics with deep learning}, series = {Data Mining and Knowledge Discovery}, volume = {37}, journal = {Data Mining and Knowledge Discovery}, number = {1}, issn = {1384-5810}, doi = {10.1007/s10618-022-00877-6}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-324213}, pages = {136-166}, year = {2023}, abstract = {Climate models are the tool of choice for scientists researching climate change. Like all models they suffer from errors, particularly systematic and location-specific representation errors. One way to reduce these errors is model output statistics (MOS) where the model output is fitted to observational data with machine learning. In this work, we assess the use of convolutional Deep Learning climate MOS approaches and present the ConvMOS architecture which is specifically designed based on the observation that there are systematic and location-specific errors in the precipitation estimates of climate models. We apply ConvMOS models to the simulated precipitation of the regional climate model REMO, showing that a combination of per-location model parameters for reducing location-specific errors and global model parameters for reducing systematic errors is indeed beneficial for MOS performance. We find that ConvMOS models can reduce errors considerably and perform significantly better than three commonly used MOS approaches and plain ResNet and U-Net models in most cases. Our results show that non-linear MOS models underestimate the number of extreme precipitation events, which we alleviate by training models specialized towards extreme precipitation events with the imbalanced regression method DenseLoss. While we consider climate MOS, we argue that aspects of ConvMOS may also be beneficial in other domains with geospatial data, such as air pollution modeling or weather forecasts.}, subject = {Klima}, language = {en} } @article{Puppe2022, author = {Puppe, Frank}, title = {Gesellschaftliche Perspektiven einer fachspezifischen KI f{\"u}r automatisierte Entscheidungen}, series = {Informatik Spektrum}, volume = {45}, journal = {Informatik Spektrum}, number = {2}, issn = {0170-6012}, doi = {10.1007/s00287-022-01443-6}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-324197}, pages = {88-95}, year = {2022}, abstract = {Die k{\"u}nstliche Intelligenz (KI) entwickelt sich rasant und hat bereits eindrucksvolle Erfolge zu verzeichnen, darunter {\"u}bermenschliche Kompetenz in den meisten Spielen und vielen Quizshows, intelligente Suchmaschinen, individualisierte Werbung, Spracherkennung, -ausgabe und -{\"u}bersetzung auf sehr hohem Niveau und hervorragende Leistungen bei der Bildverarbeitung, u. a. in der Medizin, der optischen Zeichenerkennung, beim autonomen Fahren, aber auch beim Erkennen von Menschen auf Bildern und Videos oder bei Deep Fakes f{\"u}r Fotos und Videos. Es ist zu erwarten, dass die KI auch in der Entscheidungsfindung Menschen {\"u}bertreffen wird; ein alter Traum der Expertensysteme, der durch Lernverfahren, Big Data und Zugang zu dem gesammelten Wissen im Web in greifbare N{\"a}he r{\"u}ckt. Gegenstand dieses Beitrags sind aber weniger die technischen Entwicklungen, sondern m{\"o}gliche gesellschaftliche Auswirkungen einer spezialisierten, kompetenten KI f{\"u}r verschiedene Bereiche der autonomen, d. h. nicht nur unterst{\"u}tzenden Entscheidungsfindung: als Fußballschiedsrichter, in der Medizin, f{\"u}r richterliche Entscheidungen und sehr spekulativ auch im politischen Bereich. Dabei werden Vor- und Nachteile dieser Szenarien aus gesellschaftlicher Sicht diskutiert.}, subject = {K{\"u}nstliche Intelligenz}, language = {de} } @article{RiedmannSchaperLugrin2022, author = {Riedmann, Anna and Schaper, Philipp and Lugrin, Birgit}, title = {Integration of a social robot and gamification in adult learning and effects on motivation, engagement and performance}, series = {AI \& Society}, journal = {AI \& Society}, issn = {0951-5666}, doi = {10.1007/s00146-022-01514-y}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-324208}, year = {2022}, abstract = {Learning is a central component of human life and essential for personal development. Therefore, utilizing new technologies in the learning context and exploring their combined potential are considered essential to support self-directed learning in a digital age. A learning environment can be expanded by various technical and content-related aspects. Gamification in the form of elements from video games offers a potential concept to support the learning process. This can be supplemented by technology-supported learning. While the use of tablets is already widespread in the learning context, the integration of a social robot can provide new perspectives on the learning process. However, simply adding new technologies such as social robots or gamification to existing systems may not automatically result in a better learning environment. In the present study, game elements as well as a social robot were integrated separately and conjointly into a learning environment for basic Spanish skills, with a follow-up on retained knowledge. This allowed us to investigate the respective and combined effects of both expansions on motivation, engagement and learning effect. This approach should provide insights into the integration of both additions in an adult learning context. We found that the additions of game elements and the robot did not significantly improve learning, engagement or motivation. Based on these results and a literature review, we outline relevant factors for meaningful integration of gamification and social robots in learning environments in adult learning.}, language = {en} } @article{KempfKrugPuppe2023, author = {Kempf, Sebastian and Krug, Markus and Puppe, Frank}, title = {KIETA: Key-insight extraction from scientific tables}, series = {Applied Intelligence}, volume = {53}, journal = {Applied Intelligence}, number = {8}, issn = {0924-669X}, doi = {10.1007/s10489-022-03957-8}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-324180}, pages = {9513-9530}, year = {2023}, abstract = {An important but very time consuming part of the research process is literature review. An already large and nevertheless growing ground set of publications as well as a steadily increasing publication rate continue to worsen the situation. Consequently, automating this task as far as possible is desirable. Experimental results of systems are key-insights of high importance during literature review and usually represented in form of tables. Our pipeline KIETA exploits these tables to contribute to the endeavor of automation by extracting them and their contained knowledge from scientific publications. The pipeline is split into multiple steps to guarantee modularity as well as analyzability, and agnosticim regarding the specific scientific domain up until the knowledge extraction step, which is based upon an ontology. Additionally, a dataset of corresponding articles has been manually annotated with information regarding table and knowledge extraction. Experiments show promising results that signal the possibility of an automated system, while also indicating limits of extracting knowledge from tables without any context.}, language = {en} } @article{MaiwaldBruschkeSchneideretal.2023, author = {Maiwald, Ferdinand and Bruschke, Jonas and Schneider, Danilo and Wacker, Markus and Niebling, Florian}, title = {Giving historical photographs a new perspective: introducing camera orientation parameters as new metadata in a large-scale 4D application}, series = {Remote Sensing}, volume = {15}, journal = {Remote Sensing}, number = {7}, issn = {2072-4292}, doi = {10.3390/rs15071879}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-311103}, year = {2023}, abstract = {The ongoing digitization of historical photographs in archives allows investigating the quality, quantity, and distribution of these images. However, the exact interior and exterior camera orientations of these photographs are usually lost during the digitization process. The proposed method uses content-based image retrieval (CBIR) to filter exterior images of single buildings in combination with metadata information. The retrieved photographs are automatically processed in an adapted structure-from-motion (SfM) pipeline to determine the camera parameters. In an interactive georeferencing process, the calculated camera positions are transferred into a global coordinate system. As all image and camera data are efficiently stored in the proposed 4D database, they can be conveniently accessed afterward to georeference newly digitized images by using photogrammetric triangulation and spatial resection. The results show that the CBIR and the subsequent SfM are robust methods for various kinds of buildings and different quantity of data. The absolute accuracy of the camera positions after georeferencing lies in the range of a few meters likely introduced by the inaccurate LOD2 models used for transformation. The proposed photogrammetric method, the database structure, and the 4D visualization interface enable adding historical urban photographs and 3D models from other locations.}, language = {en} } @article{FischerHarteltPuppe2023, author = {Fischer, Norbert and Hartelt, Alexander and Puppe, Frank}, title = {Line-level layout recognition of historical documents with background knowledge}, series = {Algorithms}, volume = {16}, journal = {Algorithms}, number = {3}, issn = {1999-4893}, doi = {10.3390/a16030136}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-310938}, year = {2023}, abstract = {Digitization and transcription of historic documents offer new research opportunities for humanists and are the topics of many edition projects. However, manual work is still required for the main phases of layout recognition and the subsequent optical character recognition (OCR) of early printed documents. This paper describes and evaluates how deep learning approaches recognize text lines and can be extended to layout recognition using background knowledge. The evaluation was performed on five corpora of early prints from the 15th and 16th Centuries, representing a variety of layout features. While the main text with standard layouts could be recognized in the correct reading order with a precision and recall of up to 99.9\%, also complex layouts were recognized at a rate as high as 90\% by using background knowledge, the full potential of which was revealed if many pages of the same source were transcribed.}, language = {en} } @article{KirikkayisGallikWinteretal.2023, author = {Kirikkayis, Yusuf and Gallik, Florian and Winter, Michael and Reichert, Manfred}, title = {BPMNE4IoT: a framework for modeling, executing and monitoring IoT-driven processes}, series = {Future Internet}, volume = {15}, journal = {Future Internet}, number = {3}, issn = {1999-5903}, doi = {10.3390/fi15030090}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-304097}, year = {2023}, abstract = {The Internet of Things (IoT) enables a variety of smart applications, including smart home, smart manufacturing, and smart city. By enhancing Business Process Management Systems with IoT capabilities, the execution and monitoring of business processes can be significantly improved. Providing a holistic support for modeling, executing and monitoring IoT-driven processes, however, constitutes a challenge. Existing process modeling and process execution languages, such as BPMN 2.0, are unable to fully meet the IoT characteristics (e.g., asynchronicity and parallelism) of IoT-driven processes. In this article, we present BPMNE4IoT—A holistic framework for modeling, executing and monitoring IoT-driven processes. We introduce various artifacts and events based on the BPMN 2.0 metamodel that allow realizing the desired IoT awareness of business processes. The framework is evaluated along two real-world scenarios from two different domains. Moreover, we present a user study for comparing BPMNE4IoT and BPMN 2.0. In particular, this study has confirmed that the BPMNE4IoT framework facilitates the support of IoT-driven processes.}, language = {en} } @article{WienrichCarolusMarkusetal.2023, author = {Wienrich, Carolin and Carolus, Astrid and Markus, Andr{\´e} and Augustin, Yannik and Pfister, Jan and Hotho, Andreas}, title = {Long-term effects of perceived friendship with intelligent voice assistants on usage behavior, user experience, and social perceptions}, series = {Computers}, volume = {12}, journal = {Computers}, number = {4}, issn = {2073-431X}, doi = {10.3390/computers12040077}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-313552}, year = {2023}, abstract = {Social patterns and roles can develop when users talk to intelligent voice assistants (IVAs) daily. The current study investigates whether users assign different roles to devices and how this affects their usage behavior, user experience, and social perceptions. Since social roles take time to establish, we equipped 106 participants with Alexa or Google assistants and some smart home devices and observed their interactions for nine months. We analyzed diverse subjective (questionnaire) and objective data (interaction data). By combining social science and data science analyses, we identified two distinct clusters—users who assigned a friendship role to IVAs over time and users who did not. Interestingly, these clusters exhibited significant differences in their usage behavior, user experience, and social perceptions of the devices. For example, participants who assigned a role to IVAs attributed more friendship to them used them more frequently, reported more enjoyment during interactions, and perceived more empathy for IVAs. In addition, these users had distinct personal requirements, for example, they reported more loneliness. This study provides valuable insights into the role-specific effects and consequences of voice assistants. Recent developments in conversational language models such as ChatGPT suggest that the findings of this study could make an important contribution to the design of dialogic human-AI interactions.}, language = {en} }