@article{PfitznerMayNuechter2018, author = {Pfitzner, Christian and May, Stefan and N{\"u}chter, Andreas}, title = {Body weight estimation for dose-finding and health monitoring of lying, standing and walking patients based on RGB-D data}, series = {Sensors}, volume = {18}, journal = {Sensors}, number = {5}, doi = {10.3390/s18051311}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-176642}, pages = {1311}, year = {2018}, abstract = {This paper describes the estimation of the body weight of a person in front of an RGB-D camera. A survey of different methods for body weight estimation based on depth sensors is given. First, an estimation of people standing in front of a camera is presented. Second, an approach based on a stream of depth images is used to obtain the body weight of a person walking towards a sensor. The algorithm first extracts features from a point cloud and forwards them to an artificial neural network (ANN) to obtain an estimation of body weight. Besides the algorithm for the estimation, this paper further presents an open-access dataset based on measurements from a trauma room in a hospital as well as data from visitors of a public event. In total, the dataset contains 439 measurements. The article illustrates the efficiency of the approach with experiments with persons lying down in a hospital, standing persons, and walking persons. Applicable scenarios for the presented algorithm are body weight-related dosing of emergency patients.}, language = {en} } @article{PetschkeStaab2018, author = {Petschke, Danny and Staab, Torsten E.M.}, title = {DLTPulseGenerator: a library for the simulation of lifetime spectra based on detector-output pulses}, series = {SoftwareX}, volume = {7}, journal = {SoftwareX}, doi = {10.1016/j.softx.2018.04.002}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-176883}, pages = {122-128}, year = {2018}, abstract = {The quantitative analysis of lifetime spectra relevant in both life and materials sciences presents one of the ill-posed inverse problems and, hence, leads to most stringent requirements on the hardware specifications and the analysis algorithms. Here we present DLTPulseGenerator, a library written in native C++ 11, which provides a simulation of lifetime spectra according to the measurement setup. The simulation is based on pairs of non-TTL detector output-pulses. Those pulses require the Constant Fraction Principle (CFD) for the determination of the exact timing signal and, thus, the calculation of the time difference i.e. the lifetime. To verify the functionality, simulation results were compared to experimentally obtained data using Positron Annihilation Lifetime Spectroscopy (PALS) on pure tin.}, language = {en} } @article{PetschkeStaab2019, author = {Petschke, Danny and Staab, Torsten E.M.}, title = {DDRS4PALS: a software for the acquisition and simulation of lifetime spectra using the DRS4 evaluation board}, series = {SoftwareX}, volume = {10}, journal = {SoftwareX}, doi = {10.1016/j.softx.2019.100261}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-202276}, pages = {100261}, year = {2019}, abstract = {Lifetime techniques are applied to diverse fields of study including materials sciences, semiconductor physics, biology, molecular biophysics and photochemistry. Here we present DDRS4PALS, a software for the acquisition and simulation of lifetime spectra using the DRS4 evaluation board (Paul Scherrer Institute, Switzerland) for time resolved measurements and digitization of detector output pulses. Artifact afflicted pulses can be corrected or rejected prior to the lifetime calculation to provide the generation of high-quality lifetime spectra, which are crucial for a profound analysis, i.e. the decomposition of the true information. Moreover, the pulses can be streamed on an (external) hard drive during the measurement and subsequently downloaded in the offline mode without being connected to the hardware. This allows the generation of various lifetime spectra at different configurations from one single measurement and, hence, a meaningful comparison in terms of analyzability and quality. Parallel processing and an integrated JavaScript based language provide convenient options to accelerate and automate time consuming processes such as lifetime spectra simulations.}, language = {en} } @phdthesis{Peng2019, author = {Peng, Dongliang}, title = {An Optimization-Based Approach for Continuous Map Generalization}, edition = {1. Auflage}, publisher = {W{\"u}rzburg University Press}, address = {W{\"u}rzburg}, isbn = {978-3-95826-104-4}, doi = {10.25972/WUP-978-3-95826-105-1}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-174427}, school = {W{\"u}rzburg University Press}, pages = {xv, 132}, year = {2019}, abstract = {Maps are the main tool to represent geographical information. Geographical information is usually scale-dependent, so users need to have access to maps at different scales. In our digital age, the access is realized by zooming. As discrete changes during the zooming tend to distract users, smooth changes are preferred. This is why some digital maps are trying to make the zooming as continuous as they can. The process of producing maps at different scales with smooth changes is called continuous map generalization. In order to produce maps of high quality, cartographers often take into account additional requirements. These requirements are transferred to models in map generalization. Optimization for map generalization is important not only because it finds optimal solutions in the sense of the models, but also because it helps us to evaluate the quality of the models. Optimization, however, becomes more delicate when we deal with continuous map generalization. In this area, there are requirements not only for a specific map but also for relations between maps at difference scales. This thesis is about continuous map generalization based on optimization. First, we show the background of our research topics. Second, we find optimal sequences for aggregating land-cover areas. We compare the A\$^{\!\star}\$\xspace algorithm and integer linear programming in completing this task. Third, we continuously generalize county boundaries to provincial boundaries based on compatible triangulations. We morph between the two sets of boundaries, using dynamic programming to compute the correspondence. Fourth, we continuously generalize buildings to built-up areas by aggregating and growing. In this work, we group buildings with the help of a minimum spanning tree. Fifth, we define vertex trajectories that allow us to morph between polylines. We require that both the angles and the edge lengths change linearly over time. As it is impossible to fulfill all of these requirements simultaneously, we mediate between them using least-squares adjustment. Sixth, we discuss the performance of some commonly used data structures for a specific spatial problem. Seventh, we conclude this thesis and present open problems.}, subject = {Generalisierung }, language = {en} } @article{PawellekKrmarLeistneretal.2021, author = {Pawellek, Ruben and Krmar, Jovana and Leistner, Adrian and Djajić, Nevena and Otašević, Biljana and Protić, Ana and Holzgrabe, Ulrike}, title = {Charged aerosol detector response modeling for fatty acids based on experimental settings and molecular features: a machine learning approach}, series = {Journal of Cheminformatics}, volume = {13}, journal = {Journal of Cheminformatics}, number = {1}, doi = {10.1186/s13321-021-00532-0}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-261618}, year = {2021}, abstract = {The charged aerosol detector (CAD) is the latest representative of aerosol-based detectors that generate a response independent of the analytes' chemical structure. This study was aimed at accurately predicting the CAD response of homologous fatty acids under varying experimental conditions. Fatty acids from C12 to C18 were used as model substances due to semivolatile characterics that caused non-uniform CAD behaviour. Considering both experimental conditions and molecular descriptors, a mixed quantitative structure-property relationship (QSPR) modeling was performed using Gradient Boosted Trees (GBT). The ensemble of 10 decisions trees (learning rate set at 0.55, the maximal depth set at 5, and the sample rate set at 1.0) was able to explain approximately 99\% (Q\(^2\): 0.987, RMSE: 0.051) of the observed variance in CAD responses. Validation using an external test compound confirmed the high predictive ability of the model established (R-2: 0.990, RMSEP: 0.050). With respect to the intrinsic attribute selection strategy, GBT used almost all independent variables during model building. Finally, it attributed the highest importance to the power function value, the flow rate of the mobile phase, evaporation temperature, the content of the organic solvent in the mobile phase and the molecular descriptors such as molecular weight (MW), Radial Distribution Function-080/weighted by mass (RDF080m) and average coefficient of the last eigenvector from distance/detour matrix (Ve2_D/Dt). The identification of the factors most relevant to the CAD responsiveness has contributed to a better understanding of the underlying mechanisms of signal generation. An increased CAD response that was obtained for acetone as organic modifier demonstrated its potential to replace the more expensive and environmentally harmful acetonitrile.}, language = {en} } @phdthesis{Ostermayer2017, author = {Ostermayer, Ludwig}, title = {Integration of Prolog and Java with the Connector Architecture CAPJa}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-150713}, school = {Universit{\"a}t W{\"u}rzburg}, year = {2017}, abstract = {Modern software is often realized as a modular combination of subsystems for, e. g., knowledge management, visualization, verification, or the interaction with users. As a result, software libraries from possibly different programming languages have to work together. Even more complex the case is if different programming paradigms have to be combined. This type of diversification of programming languages and paradigms in just one software application can only be mastered by mechanisms for a seamless integration of the involved programming languages. However, the integration of the common logic programming language Prolog and the popular object-oriented programming language Java is complicated by various interoperability problems which stem on the one hand from the paradigmatic gap between the programming languages, and on the other hand, from the diversity of the available Prolog systems. The subject of the thesis is the investigation of novel mechanisms for the integration of logic programming in Prolog and object-oriented programming in Java. We are particularly interested in an object-oriented, uniform approach which is not specific to just one Prolog system. Therefore, we have first identified several important criteria for the seamless integration of Prolog and Java from the object-oriented perspective. The main contribution of the thesis is a novel integration framework called the Connector Architecture for Prolog and Java (CAPJa). The framework is completely implemented in Java and imposes no modifications to the Java Virtual Machine or Prolog. CAPJa provides a semi-automated mechanism for the integration of Prolog predicates into Java. For compact, readable, and object-oriented queries to Prolog, CAPJa exploits lambda expressions with conditional and relational operators in Java. The communication between Java and Prolog is based on a fully automated mapping of Java objects to Prolog terms, and vice versa. In Java, an extensible system of gateways provides connectivity with various Prolog system and, moreover, makes any connected Prolog system easily interchangeable, without major adaption in Java.}, subject = {Logische Programmierung}, language = {en} } @article{OsmanogluKhaledAlSeiariAlKhoorietal.2021, author = {Osmanoglu, {\"O}zge and Khaled AlSeiari, Mariam and AlKhoori, Hasa Abduljaleel and Shams, Shabana and Bencurova, Elena and Dandekar, Thomas and Naseem, Muhammad}, title = {Topological Analysis of the Carbon-Concentrating CETCH Cycle and a Photorespiratory Bypass Reveals Boosted CO\(_2\)-Sequestration by Plants}, series = {Frontiers in Bioengineering and Biotechnology}, volume = {9}, journal = {Frontiers in Bioengineering and Biotechnology}, issn = {2296-4185}, doi = {10.3389/fbioe.2021.708417}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-249260}, year = {2021}, abstract = {Synthetically designed alternative photorespiratory pathways increase the biomass of tobacco and rice plants. Likewise, some in planta-tested synthetic carbon-concentrating cycles (CCCs) hold promise to increase plant biomass while diminishing atmospheric carbon dioxide burden. Taking these individual contributions into account, we hypothesize that the integration of bypasses and CCCs will further increase plant productivity. To test this in silico, we reconstructed a metabolic model by integrating photorespiration and photosynthesis with the synthetically designed alternative pathway 3 (AP3) enzymes and transporters. We calculated fluxes of the native plant system and those of AP3 combined with the inhibition of the glycolate/glycerate transporter by using the YANAsquare package. The activity values corresponding to each enzyme in photosynthesis, photorespiration, and for synthetically designed alternative pathways were estimated. Next, we modeled the effect of the crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (CETCH), which is a set of natural and synthetically designed enzymes that fix CO₂ manifold more than the native Calvin-Benson-Bassham (CBB) cycle. We compared estimated fluxes across various pathways in the native model and under an introduced CETCH cycle. Moreover, we combined CETCH and AP3-w/plgg1RNAi, and calculated the fluxes. We anticipate higher carbon dioxide-harvesting potential in plants with an AP3 bypass and CETCH-AP3 combination. We discuss the in vivo implementation of these strategies for the improvement of C3 plants and in natural high carbon harvesters.}, language = {en} } @phdthesis{Oechsner2010, author = {Oechsner, Simon}, title = {Performance Challenges and Optimization Potential of Peer-to-Peer Overlay Technologies}, doi = {10.25972/OPUS-4159}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-50015}, school = {Universit{\"a}t W{\"u}rzburg}, year = {2010}, abstract = {In today's Internet, building overlay structures to provide a service is becoming more and more common. This approach allows for the utilization of client resources, thus being more scalable than a client-server model in this respect. However, in these architectures the quality of the provided service depends on the clients and is therefore more complex to manage. Resource utilization, both at the clients themselves and in the underlying network, determine the efficiency of the overlay application. Here, a trade-off exists between the resource providers and the end users that can be tuned via overlay mechanisms. Thus, resource management and traffic management is always quality-of-service management as well. In this monograph, the three currently significant and most widely used overlay types in the Internet are considered. These overlays are implemented in popular applications which only recently have gained importance. Thus, these overlay networks still face real-world technical challenges which are of high practical relevance. We identify the specific issues for each of the considered overlays, and show how their optimization affects the trade-offs between resource efficiency and service quality. Thus, we supply new insights and system knowledge that is not provided by previous work.}, subject = {Overlay-Netz}, language = {en} } @techreport{OdhahGrassKraemer2022, type = {Working Paper}, author = {Odhah, Najib and Grass, Eckhard and Kraemer, Rolf}, title = {Effective Rate of URLLC with Short Block-Length Information Theory}, series = {W{\"u}rzburg Workshop on Next-Generation Communication Networks (WueWoWas'22)}, journal = {W{\"u}rzburg Workshop on Next-Generation Communication Networks (WueWoWas'22)}, doi = {10.25972/OPUS-28085}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-280859}, pages = {4}, year = {2022}, abstract = {Shannon channel capacity estimation, based on large packet length is used in traditional Radio Resource Management (RRM) optimization. This is good for the normal transmission of data in a wired or wireless system. For industrial automation and control, rather short packages are used due to the short-latency requirements. Using Shannon's formula leads in this case to inaccurate RRM solutions, thus another formula should be used to optimize radio resources in short block-length packet transmission, which is the basic of Ultra-Reliable Low-Latency Communications (URLLCs). The stringent requirement of delay Quality of Service (QoS) for URLLCs requires a link-level channel model rather than a physical level channel model. After finding the basic and accurate formula of the achievable rate of short block-length packet transmission, the RRM optimization problem can be accurately formulated and solved under the new constraints of URLLCs. In this short paper, the current mathematical models, which are used in formulating the effective transmission rate of URLLCs, will be briefly explained. Then, using this rate in RRM for URLLC will be discussed.}, subject = {Datennetz}, language = {en} } @article{ObremskiLugrinSchaperetal.2021, author = {Obremski, David and Lugrin, Jean-Luc and Schaper, Philipp and Lugrin, Birgit}, title = {Non-native speaker perception of Intelligent Virtual Agents in two languages: the impact of amount and type of grammatical mistakes}, series = {Journal on Multimodal User Interfaces}, volume = {15}, journal = {Journal on Multimodal User Interfaces}, number = {2}, issn = {1783-8738}, doi = {10.1007/s12193-021-00369-9}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-269984}, pages = {229-238}, year = {2021}, abstract = {Having a mixed-cultural membership becomes increasingly common in our modern society. It is thus beneficial in several ways to create Intelligent Virtual Agents (IVAs) that reflect a mixed-cultural background as well, e.g., for educational settings. For research with such IVAs, it is essential that they are classified as non-native by members of a target culture. In this paper, we focus on variations of IVAs' speech to create the impression of non-native speakers that are identified as such by speakers of two different mother tongues. In particular, we investigate grammatical mistakes and identify thresholds beyond which the agents is clearly categorised as a non-native speaker. Therefore, we conducted two experiments: one for native speakers of German, and one for native speakers of English. Results of the German study indicate that beyond 10\% of word order mistakes and 25\% of infinitive mistakes German-speaking IVAs are perceived as non-native speakers. Results of the English study indicate that beyond 50\% of omission mistakes and 50\% of infinitive mistakes English-speaking IVAs are perceived as non-native speakers. We believe these thresholds constitute helpful guidelines for computational approaches of non-native speaker generation, simplifying research with IVAs in mixed-cultural settings.}, language = {en} }