@article{HuHahnYangetal.2021,
  author    = {Hu, Chen and Hahn, Lukas and Yang, Mengshi and Altmann, Alexander and Stahlhut, Philipp and Groll, J{\"u}rgen and Luxenhofer, Robert},
  title     = {Improving printability of a thermoresponsive hydrogel biomaterial ink by nanoclay addition},
  series = {Journal of Materials Science},
  volume    = {56},
  journal   = {Journal of Materials Science},
  issn      = {0022-2461},
  doi       = {10.1007/s10853-020-05190-5},
  url       = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-234894},
  pages     = {691-705},
  year      = {2021},
  abstract  = {As a promising biofabrication technology, extrusion-based bioprinting has gained significant attention in the last decade and major advances have been made in the development of bioinks. However, suitable synthetic and stimuli-responsive bioinks are underrepresented in this context. In this work, we described a hybrid system of nanoclay Laponite XLG and thermoresponsive block copolymer poly(2-methyl-2-oxazoline)-b-poly(2-n-propyl-2-oxazine) (PMeOx-b-PnPrOzi) as a novel biomaterial ink and discussed its critical properties relevant for extrusion-based bioprinting, including viscoelastic properties and printability. The hybrid hydrogel retains the thermogelling properties but is strengthened by the added clay (over 5 kPa of storage modulus and 240 Pa of yield stress). Importantly, the shear-thinning character is further enhanced, which, in combination with very rapid viscosity recovery (~ 1 s) and structure recovery (~ 10 s), is highly beneficial for extrusion-based 3D printing. Accordingly, various 3D patterns could be printed with markedly enhanced resolution and shape fidelity compared to the biomaterial ink without added clay.},
  language  = {en}
}