Dokument-ID Dokumenttyp Verfasser/Autoren Herausgeber Haupttitel Abstract Auflage Verlagsort Verlag Erscheinungsjahr Seitenzahl Schriftenreihe Titel Schriftenreihe Bandzahl ISBN Quelle der Hochschulschrift Konferenzname Quelle:Titel Quelle:Jahrgang Quelle:Heftnummer Quelle:Erste Seite Quelle:Letzte Seite URN DOI Abteilungen OPUS4-5951 Wissenschaftlicher Artikel Schartl, Manfred; Barnekow, A.; Bauer, H.; Anders, F. Correlations of inheritance and expression between a tumor gene and the cellular homolog of the Rous sarcoma virus-transforming gene in Xiphophorus No abstract available 1982 urn:nbn:de:bvb:20-opus-61937 Theodor-Boveri-Institut für Biowissenschaften OPUS4-5952 Wissenschaftlicher Artikel Barnekow, A.; Schartl, Manfred; Anders, F.; Bauer, H. Identification of a fish protein associated with a kinase activity and related to the Rous sarcoma virus transforming protein No abstract available 1982 urn:nbn:de:bvb:20-opus-61946 Theodor-Boveri-Institut für Biowissenschaften OPUS4-6990 Wissenschaftlicher Artikel Schartl, A.; Schartl, Manfred; Anders, F. Promotion and regression of neoplasia by testosterone-promoted cell differentiation in Xiphophorus and Girardinus No abstract available. 1982 urn:nbn:de:bvb:20-opus-86684 Theodor-Boveri-Institut für Biowissenschaften OPUS4-7099 Wissenschaftlicher Artikel Schartl, Manfred; Barnekow, Angelika The expression in eukaryotes of a tyrosine kinase which is reactive with pp60v-src antibodies All specimens of Eumetazoa and Parazoa, ranging from mammals, birds, teleosts, sharks, lampreys, amphioxus, insects, down to sponges showed the pp60c-src associated kinase activity, indicating that c-src, which is the cellular homologue of the oncogene v-src of Rous sarcoma virus (RSV) is probably present in all multicellular animals. Protozoa and plants did not show pp60c-src: kinase activity. The degree of c-src expression depends on the taxonomic rank of the Eumetazoa tested, and is organ-specific with nervaus tissues displaying the highest kinase activities. In the central nervous system of mammals and birds we found a high c-src expression, and in that of the lampreys, amphioxus, and insects the lowest. Unexpectedly, total extracts of sponges showed an amount of pp60c-src kinase activity similar to that of brain cell extracts of mammals and birds. These findings suggest that pp60c-src is a phylogenetic old protein that might have evolved together with the multicellular organisation of Metazoa, and that might be of importance in proliferation and differentiation of nontransformed cells. 1982 urn:nbn:de:bvb:20-opus-86208 Theodor-Boveri-Institut für Biowissenschaften