6255
2011
eng
article
1
2012-11-13
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Popliteal Cysts in Paediatric Patients: Clinical Characteristics and Imaging Features on Ultrasound and MRI
Popliteal cysts, or Baker cysts, are considered rare in children and may exhibit particular features, as compared with adults. We studied data from80 paediatric patients with 55 Baker cysts, examined over a period of 7 years, and correlated clinical presentation with findings on ultrasonography and MRI. Prevalence of popliteal cysts was 57% in arthritic knees, 58% with hypermobility syndrome, and 28% without risk factors. Only one patient had a trauma history and showed an ipsilateral cyst. Mean cyst volume was 3.4 mL; cysts were larger in boys. Patients with arthritis had echogenic cysts in 53%. Cyst communication with the joint space was seen in 64% on ultrasonography and 86% on MRI. In conclusion, Baker cysts are a common finding in a clinically preselected paediatric population. Children with Baker cysts should be assessed for underlying arthritis and inherited joint hypermobility, while sporadic Baker cysts appear to be common, as well.
urn:nbn:de:bvb:20-opus-68662
6866
In: Arthritis (2011), Article ID 751593, 7 p.; DOI:10.1155/2011/751593
Henning Neubauer
Henner Morbach
Tobias Schwarz
Clemens Wirth
Hermann Girschick
Meinrad Beer
deu
swd
Medizin
Medizin und Gesundheit
open_access
Institut für diagnostische und interventionelle Radiologie (Institut für Röntgendiagnostik)
Förderzeitraum 2011
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/6255/Neubauer091_751593.pdf
6133
2012
deu
doctoralthesis
1
2012-09-04
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2012-07-24
Klinische Wertigkeit der funktionellen Magnetresonanzurographie bei Kindern
Value of semi-automated functional MR-Urography in clincal routine
Die vorliegende retrospektive Arbeit zeigt die Einsatzmöglichkeiten der funktionellen Magnetresonanzurographie bei Kindern auf. Mit Hilfe der verwendeten Software lassen sich die funktionellen Aspekte der Untersuchung wenig zeitintensiv bearbeiten und die Ergebnisse anschaulich und verständlich darstellen. Die Beurteilung der funktionellen Ergebnisse erlaubt aus der Zusammenschau von errechneten definierten metrischen Daten der Untersuchung und der Kurvenanalyse eine Aussage zur seitengetrennten Nierenfunktion. Diese korreliert gut mit dem klinischen Ergebnis und der MAG 3 Szintigraphie als Standardverfahren. Als Funktionsparameter zur Unterscheidung zwischen normal funktionierender und dekompensierter obstruierter Nierenuretereinheit dient in erster Linie die renale Transitzeit des Kontrastmittels RTT. Durch Einführung einer Pseudonativsequenz konnten im Patientenkollektiv Untersuchungen der Auswertung zugeführt werden, die primär nicht auszuwerten waren. Eine Korrelation der errechneten Patlakzahl mit der geschätzten glomulären Filtrationsrate ließ sich in unserem Kollektiv nicht nachweisen. Insgesamt ist das Verfahren im klinischen Alltag weiter zu evaluieren, Prospektive Studien sollten eine eventuelle Überlegenheit dieser strahlenfreien Methode gegenüber der Szintigraphie als zentrale Fragestellung überprüfen.
Retrospective functional assessment of MRU examinations between 2004 and 2011. Calculated functional parameters and curves were interpreted as normal (group 1), equivocal (group 2) or obstructed (group 3), followed by comparison with clinical outcome (SOR) and, if available, MAG 3 scintigraphy. CHOP-fMRU is a valuable tool to assess functional parameters in fMRU. CTT and RTT can help to differenciate between obstructed and normal KUU. Further prospective studies should evaluate the performance of fMRU compared to scintigraphy in children, in order to appraise the additional functional value of fMRU beyond morphological information.
urn:nbn:de:bvb:20-opus-72593
7259
X124181
Deutsches Urheberrecht
Clemens Wirth
deu
swd
Funktionelle NMR-Tomographie
deu
uncontrolled
Kinderradiologie
eng
uncontrolled
MR-Urography Pediatric
Medizin und Gesundheit
open_access
Institut für diagnostische und interventionelle Radiologie (Institut für Röntgendiagnostik)
Universität Würzburg
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/6133/Klinische_Wertigkeit_der_funktionellen_Magnetresonanzurographie.pdf
12396
2012
eng
527989
2012
article
1
2016-01-11
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Acute Muscle Trauma due to Overexercise in an Otherwise Healthy Patient with Cystic Fibrosis
Cystic fibrosis (CF) is one of the most common inherited diseases and is caused by mutations in the CFTR gene. Although the pulmonary and gastrointestinal manifestations of the disease remain in the focus of treatment, recent studies have shown expression of the CFTR gene product in skeletal muscle cells and observed altered intramuscular \(Ca^{2+}\) release dynamics in CFTR-deficient animal models. Physical exercise is beneficial for maintaining fitness and well-being in CF patients and constitutes one aspect of modern multimodal treatment, which has considerably increased life span and reduced morbidity. We report on a case of acute muscle trauma resulting from excessive dumbbell exercise in a young adult with cystic fibrosis and describe clinical, laboratory and imaging characteristics of acute exercise-induced muscle injury.
Case Reports in Pediatrics
PMC3350114
urn:nbn:de:bvb:20-opus-123967
Case Reports in Pediatrics 2012 Article ID 527989. doi:10.1155/2012/527989
Henning Neubauer
Clemens Wirth
Katharina Ruf
Helge Hebestreit
Meinrad Beer
eng
uncontrolled
Cystic fibrosis
Gynäkologie, Geburtsmedizin, Pädiatrie, Geriatrie
open_access
Kinderklinik und Poliklinik
Institut für diagnostische und interventionelle Radiologie (Institut für Röntgendiagnostik)
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/12396/Neubauer_CaseReportPediatrics.pdf
11047
2014
eng
article
1
2015-02-26
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Thrombosis as a complication of central venous access in pediatric patients with malignancies: a 5-year single-center experience
Background
Reliable central venous access (CVC) is essential for hematology–oncology patients since frequent puncture of peripheral veins—e.g., for chemotherapy, antibiotic administration, repeated blood sampling, and monitoring—can cause unacceptable pain and psychological trauma, as well as severe side effects in cases of extravasation of chemotherapy drugs. However, CVC lines still carry major risk factors, including thrombosis, infection (e.g., entry site, tunnel, and luminal infections), and catheter dislocation, leakage, or breakage.
Methods
Here we performed a retrospective database analysis to determine the incidence of CVC-associated thrombosis in a single-center cohort of 448 pediatric oncologic patients, and to analyze whether any subgroup of patients was at increased risk and thus might benefit from prophylactic anticoagulation.
Results
Of the 448 patients, 269 consecutive patients received a CVC, and 55 of these 269 patients (20%) also had a thrombosis. Of these 55 patients, 43 had at least one CVC-associated thrombosis (total number of CVC-associated thrombosis: n = 52). Among all patients, the median duration of CVC exposure was 464 days. Regarding exposure time, no significant difference was found between patients with and without CVC-associated thrombosis. Subclavia catheters and advanced tumor stages seem to be the main risk factors for the development of CVC-associated thrombosis, whereas pharmacologic prophylaxis did not seem to have a relevant impact on the rate of thrombosis.
Conclusions
We conclude that pediatric surgeons and oncologists should pay close attention to ensuring optimal and accurate CVC placement, as this appears the most effective tool to minimize CVC-associated complications.
10.1186/2052-1839-14-18
urn:nbn:de:bvb:20-opus-110476
In: BMC Hematology 2014, 14:18. doi:10.1186/2052-1839-14-18
Verena Wiegering
Sophie Schmid
Oliver Andres
Clemens Wirth
Armin Wiegering
Thomas Meyer
Beate Winkler
Paul G. Schlegel
Matthias Eyrich
eng
uncontrolled
Pediatric malignancy
eng
uncontrolled
Central venous access
eng
uncontrolled
Port
eng
uncontrolled
Hickman catheter
eng
uncontrolled
Thrombosis
Medizin und Gesundheit
open_access
Klinik und Poliklinik für Allgemein-, Viszeral-, Gefäß- und Kinderchirurgie (Chirurgische Klinik I)
Kinderklinik und Poliklinik
Klinik und Poliklinik für Nuklearmedizin
Förderzeitraum 2014
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/11047/067_Wiegering_BMCHeamatology.pdf