2682
1974
eng
conferenceobject
1
2009-01-12
--
--
Morphology of nucleolar cistrons in a plant cell, Acetabularia mediterranea
The structural organization of transcriptionally active DNA that contains cistrons for precursor molecules of ribosomal RNA is described in positively stained spread preparations from nuclei and nucleoli isolated from the green alga, Acetabularia mediterranea Lmx. These nuclei contain large aggregates of nucleolar subunits in which fibril-covered regions, the putative active cistrons for precursors of ribosomal RNA, alternate with fibril-free intercepts, the "spacers". The length distribution of the different intercepts of this DNA is given, and the pattern is compared with those shown in animal cell systems. The data are discussed in relation to problems of transcription and of amplification of ribosomal RNA genes.
urn:nbn:de:bvb:20-opus-32213
3221
In: Proc. Natl. Acad. Sci. (1974), 71, 3626-3630.
Michael F. Trendelenburg
Herbert Spring
Ulrich Scheer
Werner W. Franke
eng
uncontrolled
ribosomal RNA genes; electron microscopy; spread preparations
Biowissenschaften; Biologie
open_access
Theodor-Boveri-Institut für Biowissenschaften
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/2682/Scheer_Morphology_cistrons.pdf
3091
1974
eng
conferenceobject
1
2009-08-26
--
--
Pathways of nucleocytoplasmic translocation of ribonucleoproteins
No abstract available
urn:nbn:de:bvb:20-opus-33832
3383
In: Transport at the cellular level. - Cambridge: Univ. Press, 1974. - ISBN: 0-521-20470-4. - (Symposia of the Society for Experimental Biology ; 28), 249-282.
Werner W. Franke
Ulrich Scheer
Biowissenschaften; Biologie
open_access
Theodor-Boveri-Institut für Biowissenschaften
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3091/Scheer_Pathways.pdf
4351
1975
deu
conferenceobject
1
2010-11-04
--
--
Kommunikation und Schlußfolgerung über nichtsprachliches Verhalten
No abstract available
urn:nbn:de:bvb:20-opus-50207
5020
In: Bericht über den 29. Kongreß der Deutschen Gesellschaft für Psychologie in Salzburg 1974, Bd. 1 / hrsg. von Werner H. Tack. - Göttingen u.a. : Verl. für Psychologie, Hogrefe. - 1975, S. 279-281.
Deutsches Urheberrecht
Johann Heinrich Ellgring
deu
swd
Psychologie
Psychologie
open_access
Institut für Psychologie
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/4351/Ellgring_Kommunikation_SchlussfolgerungKopie1.pdf
3092
1975
eng
conferenceobject
1
2009-08-26
--
--
Ultrastructure of transcription in the nucleoli of the green algae Acetabularia major and A. mediterranea
No abstract available
urn:nbn:de:bvb:20-opus-33779
3377
In: Biochemistry of the cell nucleus : Mechanism and regulation of gene expression / Hrsg. von Egon J. Hidvégi et al. - North-Holland : American Elsevier, 1975 (Federation of European Biochemical Societies: FEBS Meeting ; 33=9. meeting), 159-168.
M. F. Trendelenburg
Werner W. Franke
H. Spring
Ulrich Scheer
Biowissenschaften; Biologie
open_access
Theodor-Boveri-Institut für Biowissenschaften
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3092/Scheer_Ultrastructure.pdf
3093
1975
eng
conferenceobject
1
2009-08-26
--
--
Biochemical and structural aspects of nucleocytoplasmic transfer of ribonucleoproteins at the nuclear envelope level: facts and theses
No abstract available
urn:nbn:de:bvb:20-opus-33766
3376
In: Biochemistry of the cell nucleus : Mechanism and regulation of gene expression / Hrsg. von Egon J. Hidvégi et al. - North-Holland : American Elsevier, 1975 (Federation of European Biochemical Societies: FEBS Meeting ; 33=9. meeting), 205-211
Werner W. Franke
Ulrich Scheer
Biowissenschaften; Biologie
open_access
Theodor-Boveri-Institut für Biowissenschaften
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3093/Scheer_Biochemical.pdf
4393
1976
eng
conferenceobject
1
2010-11-17
--
--
The new approach to tRNA primary structure determination : the primary structure of valine tRNA\(^{Val}_{2b}\)
The new combination of TLC and high voltage electrophoresis on cooling plate is described.We have applied this technique to study of primary structure of tRNA.Preliminary sequence of baker's yeast tRNA^Val_2b is described. New approach to preparation of large tRNA fragments is demonstrated.
urn:nbn:de:bvb:20-opus-50920
5092
International Conference on the "Synthesis, Structure and Chemistry of Transfer Ribonucleic Acids and their Components" ; (Dymaczewo near Poznań) : 13.-17.09.1976 / [Hrsg.] Maciej Wiewiórowski (1976), 456-470
Deutsches Urheberrecht
V. D. Axelrod
Valentin G. Gorboulev
T. V. Kutateladze
J. Barciszewski
A. A. Bayev
deu
swd
RNS
Medizin und Gesundheit
open_access
Institut für Anatomie und Zellbiologie
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/4393/Gorboulev_new_approach_tRNA.pdf
3090
1976
deu
conferenceobject
1
2009-08-26
--
--
On the existence of arrested transcriptional machinery in late stages of avian erythropoiesis
No abstract available
urn:nbn:de:bvb:20-opus-33696
3369
In: Progress in Differentiation Research : Proceedings of the Second Internat. Conference on Differentiation, Copenhagen, Denmark, 8-12 Sept., 1975 / hrsg. von N. Müller-Bérat. - Amsterdam: North-Holland Publ., 1976, 119-123.
Hanswalter Zentgraf
Ulrich Scheer
Werner W. Franke
Biowissenschaften; Biologie
open_access
Theodor-Boveri-Institut für Biowissenschaften
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3090/Scheer_Existence.pdf
3094
1976
eng
conferenceobject
1
2009-08-26
--
--
Regulation of transcription of ribosomal RNA genes during amphibian oogenesis
No abstract available
urn:nbn:de:bvb:20-opus-33700
3370
In: Progress in Differentiation Research : Proceedings of the Second Internat. Conference on Differentiation, Copenhagen, Denmark, 8-12 Sept., 1975 / hrsg. von N. Müller-Bérat. - Amsterdam: North-Holland Publ., 1976, 105-128.
Ulrich Scheer
M. F. Trendelenburg
Werner W. Franke
Biowissenschaften; Biologie
open_access
Theodor-Boveri-Institut für Biowissenschaften
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3094/Scheer_Regulation.pdf
3612
1976
eng
conferenceobject
1
2010-01-27
--
--
Transcriptional complexes of nucleolar genes
No abstract available
urn:nbn:de:bvb:20-opus-41072
4107
In: Electron microscopy 1976 : proceedings of the Sixth European Congress on Electron Microscopy : Vol. 2 ; Biological sciences. - Jerusalem : TAL Internat. Publ., 1976, S.16 - 32.
Ulrich Scheer
Werner W. Franke
Biowissenschaften; Biologie
open_access
Theodor-Boveri-Institut für Biowissenschaften
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3612/Scheer_Transcriptional_nucleolar.pdf
3645
1976
deu
conferenceobject
1
2010-02-05
--
--
Kommunikatives Verhalten im Verlauf depressiver Erkrankungen
No abstract available
urn:nbn:de:bvb:20-opus-43123
4312
In: Bericht über den 30. Kongreß der Deutschen Gesellschaft für Psychologie in Regensburg 1976 / hrsg. von Werner H. Tack. - Göttingen [u.a.] : Verlag für Psychologie Hogrefe, 1977. - ISBN: 3-8017-0132-8, Bd. 2, 190 - 192.
Johann Heinrich Ellgring
Psychologie
open_access
Institut für Psychologie (bis Sept. 2007)
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3645/Ellgring_Kommunikatives_Verhalten.pdf
3662
1976
deu
conferenceobject
1
2010-02-11
--
--
Abtastrate und systematische Verhaltensbeobachtung
No abstract available
urn:nbn:de:bvb:20-opus-43147
4314
In: Bericht über den 30. Kongreß der Deutschen Gesellschaft für Psychologie in Regensburg 1976 / hrsg. von Werner H. Tack. - Göttingen [u.a.] : Verlag für Psychologie Hogrefe, 1977. - ISBN: 3-8017-0131-X, Bd. 1, 326-327.
Johann Heinrich Ellgring
Andrew Clarke
Psychologie
open_access
Institut für Psychologie (bis Sept. 2007)
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3662/Ellgring_Abtastrate.pdf
3646
1976
deu
conferenceobject
1
2010-02-05
--
--
Verhaltensanalyse sozialer Interaktion
No abstract available
urn:nbn:de:bvb:20-opus-43131
4313
In: Bericht über den 30. Kongreß der Deutschen Gesellschaft für Psychologie in Regensburg 1976 / hrsg. von Werner H. Tack. - Göttingen [u.a.] : Verlag für Psychologie Hogrefe, 1977. - ISBN: 3-8017-0131-X, Bd. 1, 334 - 335.
Johann Heinrich Ellgring
K. R. Scherer
Psychologie
open_access
Institut für Psychologie (bis Sept. 2007)
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3646/Ellgring_Verhaltensanalyse_Interaktion.pdf
3775
1977
deu
conferenceobject
1
2010-03-09
--
--
Konfigurale Klassifikation von Delinquenten durch Variablen der Therapiemotivation
No abstract available
4350
urn:nbn:de:bvb:20-opus-43501
In: Bericht über den 30. Kongress der Deutschen Gesellschaft für Psychologie in Regensburg 1976 / ... hrsg. von Werner H. Tack, Bd. 2. - Göttingen [u.a.] : Verlag für Psychologie Hogrefe, 1977. - ISBN: 3-8017-0131-X, S. 395-397.
Wilfried Hommers
Max Steller
deu
swd
Psychologie
deu
swd
Kongress
Psychologie
open_access
Institut für Psychologie
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3775/Hommers_Konfigurale_Klassifikation.pdf
4039
1977
deu
conferenceobject
1
2010-06-24
--
--
Ein Bayes-statistischer Vergleich probabilistischer Modelle für das Entscheidungsverhalten von Schulkindern und Studenten
No abstract available
urn:nbn:de:bvb:20-opus-44206
4420
In: Bericht über den 30. Kongress der Deutschen Gesellschaft für Psychologie in Regensburg 1976 / ... hrsg. von Werner H. Tack. - Göttingen [u.a.] : Verlag für Psychologie Hogrefe, 1977. - Bd. 1, S. 75-77. - ISBN: 3-8017-0131-X
Wilfried Hommers
deu
swd
Psychologie / Kongress / Zeitschrift
Psychologie
open_access
Institut für Psychologie (bis Sept. 2007)
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/4039/Hommers_Bayes_statistischer_Vergleich.pdf
3367
1978
eng
conferenceobject
1
2009-11-18
--
--
Supranucleosomal and non-nucleosomal chromatin configurations
A significant contribution to the understanding of chromatin organization was the d iscovery of the nucleosome as a globular repeating unit of the package of DNA (Hewish and Burgoyne, 1973; Woodcock, 1973; Kornberg, 1974; Olins and Olins, 1974; for review see Oudet et al., 1978 a) . In accord with the original definition and in ag reement with most workers in this field of research we identify a nucleosome as a spheric alor slightly oblate gr anular particle 10-13 nm in diameter, containing about 200 base pairs of DNA and two of each of the four his tones H2a, H2b, H3 and H4. It is this structure in which the bulk of the nuclear chroma tin is organized in most eukaryotic cells, with the exception of the dinofl age llates (Rae and Steele, 1977; dinofl agellate DNA, however, c an be packed into nucleosoma l structures in vitro by addition of the appropriate amounts of histones;the same reference). Although it seems clear from the work reported that condensed and transcriptiona lly inactive chroma tin is contained in nucleosomes as the principle for first order p acking of DNA there are two important questions onto which we are focusing in the present study: ( i ) What is the higher order of p a cking present in - and perhaps typical-of - the condensed sta te of chromatin, and (ii) what is the specific form of arrangement of transcriptionally a ctive chromatin?
urn:nbn:de:bvb:20-opus-39447
3944
In: Ninth International Congress on Electron Microscopy, Toronto, Vol. III: State of the art symposia / J.M. Sturgess [Hrsg.]. - Toronto : Microscopical Soc. of Canada, 1978. - ISBN: 0-920622-08-9, S. 573-586.
Werner W. Franke
Hanswalter Zentgraf
Ulrich Scheer
Biowissenschaften; Biologie
open_access
Theodor-Boveri-Institut für Biowissenschaften
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3367/Scheer_Supranucleosomal_Configurations.pdf
6833
1978
eng
conferenceobject
1
2013-11-06
--
--
Extrapolation of carcinogenicity data to low doses with a dose-response study of the binding of benzo(a)pyrene to rat liver DNA
The binding of tritiated benzo(a)pyrene (BP) to liver DNA of 25 adult male rats (SIV 50) has been determined 50 h after a single intraperitoneal injection of doses between 40 ug/kg and 4; mg/kg. The dose-response relations~ ip is linear up to i mg/kg, shows a sigmoid step towards 2 mg/kg and a shallow linear. slope above that value. TlJe 0 bserved bin ding ranges from 1.7 to 180 nmoles BP per mole DNA phosphate. The non-linearity between 1 and 2 mg/kg could be explained 0):1 the basis of an induction of metabolizing enzymes. A pure1y mathematical extrapolation of therumour incidence from a carcinogenic dose (1 x 40mg/kg for a 20% hepatoma incidence in newborn mice) to human exposure levels (aboilt 0.1 ug/kg per day) would never have followed a step like the on~ found in our experiments. Our dose-effect study therefore shows how carcinogenitity data could be extrapolated in a biologically founded way to low doses.
urn:nbn:de:bvb:20-opus-80157
8015
In: Toxieological Aspects of Food Safety : proc. of the European Society of Toxicology ; meeting held in Copenhagen, June 19 - 22, 1977 / Hrsg.: Leonard, B. - Berlin : Springer, 1978. - [Archives of toxicology / Supplement] ; 1 - ISBN: 3-540-08646-3, p. 369-71.
Deutsches Urheberrecht
Werner K. Lutz
C. Schlatter
deu
swd
Toxikologie
Medizin und Gesundheit
open_access
Institut für Pharmakologie und Toxikologie
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/6833/Lutz76.pdf
3610
1978
eng
conferenceobject
1
2010-01-27
--
--
Morphology of transcriptionally active chromatin
Some decades ago it was noted by cytologists that within the interphase nucleus large portions of the transcriptionally ("genetically," in their terms) inactive chromosomal material are contained in aggregates of condensed chromatin, the "chromocenters," whereas transcriptionally active regions of chromosomes appear in a more dispersed form and are less intensely stained with DNA-directed staining procedures (Heitz 1929, 1932, 1956; Bauer 1933). The hypothesis that condensed chromatin is usually characterized by very low or no transcriptional activity, and that transcription occurs in loosely packed forms of chromatin (including, in most cells, the nucleolar chromatin) has received support from studies of ultrathin sections in the electron microscope and from the numerous attempts to separate transcriptionally active from inactive chromatin biochemically (for references, see Anderson et al. 1975; Berkowitz and Doty 1975; Krieg and Wells 1976; Rickwood and Birnie 1976; Gottesfeld 1977). Electron microscopic autoradiography has revealed that sites of RNA synthesis are enriched in dispersed chromatin regions located at the margins of condensed chromatin (Fakan and Bernhard 1971, 1973; Bouteille et al. 1974; Bachellerie et al. 1975) and are characterized by the occurrence of distinct granular and fibrillar ribonucleoprotein (RNP) structures, such as perichromatin granules and fibrils. The discovery that, in most eukaryotic nuclei, major parts of the chromatin are organized in the form of nucleosomes (Olins and Olins 1974; Kornberg 1974; Baldwin et al. 1975) has raised the question whether the same nucleosomal packing of DNA is also present in transcriptionally active chromatin strands. Recent detailed examination of the morphology of active and inactive chromatin involving a diversity of electron microscopic methods, particularly the spreading technique by Miller and coworkers (Miller and Beatty 1969; Miller and Bakken 1972), has indicated that the DNA of some actively transcribed regions is not packed into nucleosomal particles but is present in a rather extended form within a relatively thin (4-7 nm) chromatin fiber.
urn:nbn:de:bvb:20-opus-41097
4109
In: Chromatin ; Teil 2 / Cold Spring Harbor Laboratory <Cold Spring Harbor>. - 1978. - (Cold Spring Harbor Symposia on Quantitative Biology ; 42), S. 755 - 772.
Werner W. Franke
Ulrich Scheer
Michael F. Trendelenburg
H. Zentgraf
H. Spring
Biowissenschaften; Biologie
open_access
Theodor-Boveri-Institut für Biowissenschaften
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3610/Scheer_Morphology_active_chromatin.pdf
3296
1978
deu
conferenceobject
1
2009-11-04
--
--
Verfahren zur halbautomatischen Bearbeitung von Videoaufzeichnungen
No abstract available
urn:nbn:de:bvb:20-opus-33750
3375
In: Fernsehen in der Psychiatrie : Symposion Berlin, Oktober 1977 / hrsg. von Hanfried Helmchen. Mit Beitr. von K. Abt ... - Stuttgart: Thieme, 1978. - ISBN: 3-13-570701-6, S. 107-115
A. H. Clarke
Johann Heinrich Ellgring
Psychologie
open_access
Institut für Psychologie (bis Sept. 2007)
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3296/Ellgring_Verfahren.pdf
3295
1978
deu
conferenceobject
1
2009-11-04
--
--
Verlaufsbeobachtungen anhand standardisierter Videoaufzeichnungen bei depressiven Patienten
No abstract available
urn:nbn:de:bvb:20-opus-33744
3374
In: Fernsehen in der Psychiatrie : Symposion Berlin, Oktober 1977 / hrsg. von Hanfried Helmchen. Mit Beitr. von K. Abt ... - Stuttgart: Thieme, 1978. - ISBN: 3-13-570701-6, S. 68-77
Johann Heinrich Ellgring
A. H. Clarke
Psychologie
open_access
Institut für Psychologie (bis Sept. 2007)
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/3295/Ellgring_Verlaufsbeobachtungen.pdf
6818
1979
eng
conferenceobject
1
2013-10-21
--
--
Modulation of the in vivo covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA by selective induction of microsomal and nuclear aryl hydrocarbon hydroxylase activity
The influence of microsomal (mAHH) and nuclear (nAHH) aryl hydrocarbon hydroxylase activity on the covalent binding of t:titiated benzo(a)pyrene to rat liver DNA was evaluated in vivo. Induction ofmAHH was obtained after phenobarbitone treatment (180% of control), which increased DNA binding to 210%, but left the nAHH unchanged. mAHH and nAHH were slightly indilced with dieldrin (130% and 120%), but the binding remairred unchanged. The increasing effect of mAHlt as weil as the possibly decreasing effect of nAHH induction on the binding became obvious when the data of 11 individual rats were used to solve the equation Binding = aX(mAHH) + bX(nAHH) + c. Multiple linear regression analysis resulted in positive values for a and c, a negative value for b, and a multiple correlation coefficient R = 0.82. An influence of other enzymes involved in the metabolism of benzo(a)pyrene cannot be excluded. The Study shows clearly that the binding of a foreign compound to DNA in vivo is not only dependent on microsomal enzyme activities but also on nuclear activities even if the latter are considerably lower than those of mic'rosomes.
urn:nbn:de:bvb:20-opus-80132
8013
In: Mechanism of toxic action on some target organs : drugs and other substances ; proc. of the Europ. Soc. of Toxicology ; meeting held in Berlin (West), june 25 - 28, 1978 / Chambers, Philip L. - Berlin: Springer, 1979. - [Archives of toxicology / Supplement] ; 2; ISBN: 3-540-09305-2, p. 285-8.
Deutsches Urheberrecht
A. Viviani
Werner K. Lutz
deu
swd
DNA
eng
uncontrolled
Benzo(a)pyrene
eng
uncontrolled
DNA-Binding
eng
uncontrolled
Carcinogen
eng
uncontrolled
Enzyme
eng
uncontrolled
Induction
eng
uncontrolled
Aryl Hydrocarbon Hydroxylase
eng
uncontrolled
Rats
eng
uncontrolled
Phenobarbitone
eng
uncontrolled
Dieldrin
Medizin und Gesundheit
open_access
Institut für Anatomie und Zellbiologie
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/6818/Lutz70.pdf