12188
2013
eng
180
14
article
1
2015-11-12
--
--
Recognition of depression and anxiety and their association with quality of life, hospitalization and mortality in primary care patients with heart failure - study protocol of a longitudinal observation study
Background: International disease management guidelines recommend the regular assessment of depression and anxiety in heart failure patients. Currently there is little data on the effect of screening for depression and anxiety on the quality of life and the prognosis of heart failure (HF). We will investigate the association between the recognition of current depression/anxiety by the general practitioner (GP) and the quality of life and the patients' prognosis.
Methods/Design: In this multicenter, prospective, observational study 3,950 patients with HF are recruited by general practices in Germany. The patients fill out questionnaires at baseline and 12-month follow-up. At baseline the GPs are interviewed regarding the somatic and psychological comorbidities of their patients. During the follow-up assessment, data on hospitalization and mortality are provided by the general practice. Based on baseline data, the patients are allocated into three observation groups: HF patients with depression and/or anxiety recognized by their GP (P+/+), those with depression and/or anxiety not recognized (P+/-) and patients without depression and/or anxiety (P-/-). We will perform multivariate regression models to investigate the influence of the recognition of depression and/or anxiety on quality of life at 12 month follow-up, as well as its influences on the prognosis (hospital admission, mortality).
Discussion: We will display the frequency of GP-acknowledged depression and anxiety and the frequency of installed therapeutic strategies. We will also describe the frequency of depression and anxiety missed by the GP and the resulting treatment gap. Effects of correctly acknowledged and missed depression/anxiety on outcome, also in comparison to the outcome of subjects without depression/anxiety will be addressed. In case results suggest a treatment gap of depression/anxiety in patients with HF, the results of this study will provide methodological advice for the efficient planning of further interventional research.
BMC Family Practice
10.1186/1471-2296-14-180
1471-2296
urn:nbn:de:bvb:20-opus-121881
BMC Family Practice 2013, 14:180. doi:10.1186/1471-2296-14-180
Marion Eisele
Eva Blozik
Stefan Störk
Jens-Martin Träder
Christoph Herrmann-Lingen
Martin Scherer
eng
uncontrolled
anxiety
eng
uncontrolled
depression
eng
uncontrolled
health care research
eng
uncontrolled
heart failure
eng
uncontrolled
prevalence
eng
uncontrolled
observational study
eng
uncontrolled
prognosis
eng
uncontrolled
quality of life
eng
uncontrolled
hospitalization
eng
uncontrolled
treatment
eng
uncontrolled
mortality
eng
uncontrolled
task force
eng
uncontrolled
health questionnaire
eng
uncontrolled
cardiovascular care
eng
uncontrolled
validity
eng
uncontrolled
scale
eng
uncontrolled
validation
eng
uncontrolled
outcomes
eng
uncontrolled
standardization
eng
uncontrolled
population
Krankheiten
open_access
Medizinische Klinik und Poliklinik I
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/12188/006_Eisele_BMC_Family_Practice.pdf
17244
2017
eng
18
article
1
2018-11-21
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--
General practitioners' awareness of depressive symptomatology is not associated with quality of life in heart failure patients - cross-sectional results of the observational RECODE-HF Study
Background
Depression is a common comorbidity in patients with chronic heart failure (HF) and linked to a wider range of symptoms which, in turn, are linked to a decreased health-related quality of life (HRQOL). Treatment of depression might improve HRQOL but detecting depression is difficult due to the symptom overlap between HF and depression. Therefore, clinical guidelines recommend to routinely screen for depression in HF patients. No studies have so far investigated the treatment after getting aware of a depressive symptomatology and its correlation with HRQOL in primary care HF patients. Therefore, we examined the factors linked to depression treatment and those linked to HRQOL in HF patients. We hypothesized that GPs’ awareness of depressive symptomatology was associated with depression treatment and HRQOL in HF patients.
Methods
For this observational study, HF patients were recruited in primary care practices and filled out a questionnaire including PHQ-9 and HADS. A total of 574 patients screened positive for depressive symptomatology. Their GPs were interviewed by phone regarding the patients’ comorbidities and potential depression treatment. Descriptive and regression analysis were performed.
Results
GPs reported various types of depression treatments (including dialogue/counselling by the GP him/herself in 31.8% of the patients). The reported rates differed considerably between GP-reported initiated treatment and patient-reported utilised treatment regarding psychotherapy (16.4% vs. 9.5%) and pharmacotherapy (61.2% vs. 30.3%). The GPs' awareness of depressive symptomatology was significantly associated with the likelihood of receiving pharmacotherapy (OR 2.8; p < 0.001) but not psychotherapy. The patient’s HRQOL was not significantly associated with the GPs' awareness of depression.
Conclusion
GPs should be aware of the gap between GP-initiated and patient-utilised depression treatments in patients with chronic HF, which might lead to an undersupply of depression treatment. It remains to be investigated why GPs’ awareness of depressive symptomatology is not linked to patients’ HRQOL. We hypothesize that GPs are aware of cases with reduced HRQOL (which improves under depression treatment) and unaware of cases whose depression do not significantly impair HRQOL, resulting in comparable levels of HRQOL in both groups. This hypothesis needs to be further investigated.
BMC Family Practice
10.1186/s12875-017-0670-9
29221442
urn:nbn:de:bvb:20-opus-172445
BMC Family Practice (2017) 18:100. https://doi.org/10.1186/s12875-017-0670-9
true
true
CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International
Marion Eisele
Sigrid Boczor
Anja Rakebrandt
Eva Blozik
Jens-Martin Trader
Stefan Stork
Christoph Herrmann-Lingen
Martin Scherer
eng
uncontrolled
Medicine
eng
uncontrolled
Depression
eng
uncontrolled
Heart failure
eng
uncontrolled
Recognition of depression
eng
uncontrolled
Quality of life
eng
uncontrolled
Depression treatment
eng
uncontrolled
Observational study
eng
uncontrolled
Primary care
eng
uncontrolled
Healthcare research
eng
uncontrolled
Depressive symptomatology
Medizin und Gesundheit
open_access
Medizinische Klinik und Poliklinik I
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/17244/Eisele_s12875-017-0670-9.pdf