12134
2014
eng
13-32
96
article
1
2015-10-28
--
--
Treatment of invasive fungal infections in cancer patients—updated recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
Invasive fungal infections are a main cause of morbidity and mortality in cancer patients undergoing intensive chemotherapy regimens. Early antifungal treatment is mandatory to improve survival. Today, a number of effective and better-tolerated but more expensive antifungal agents compared to the former gold standard amphotericin B deoxycholate are available. Clinical decision-making must consider results from numerous studies and published guidelines, as well as licensing status and cost pressure. New developments in antifungal prophylaxis improving survival rates result in a continuous need for actualization. The treatment options for invasive Candida infections include fluconazole, voriconazole, and amphotericin B and its lipid formulations, as well as echinocandins. Voriconazole, amphotericin B, amphotericin B lipid formulations, caspofungin, itraconazole, and posaconazole are available for the treatment of invasive aspergillosis. Additional procedures, such as surgical interventions, immunoregulatory therapy, and granulocyte transfusions, have to be considered. The Infectious Diseases Working Party of the German Society of Hematology and Oncology here presents its 2008 recommendations discussing the dos and do-nots, as well as the problems and possible solutions, of evidence criteria selection.
Annals of Hematology
10.1007/s00277-013-1867-1
24026426
urn:nbn:de:bvb:20-opus-121340
Annals of Hematology (2014) 93:13–32 DOI 10.1007/s00277-013-1867-1
Sabine Mousset
Dieter Buchheidt
Werner Heinz
Markus Ruhnke
Oliver A. Cornely
Gerlinde Egerer
William Krüger
Hartmut Link
Silke Neumann
Helmut Ostermann
Jens Panse
Olaf Penack
Christina Rieger
Martin Schmidt-Hieber
Gerda Silling
Thomas Südhoff
Andrew J. Ullmann
Hans-Heinrich Wolf
Georg Maschmeyer
Angelika Böhme
eng
uncontrolled
cancer
eng
uncontrolled
invasive fungal infections
eng
uncontrolled
antifungals
eng
uncontrolled
mycoses
eng
uncontrolled
hematologic malignancies
eng
uncontrolled
aspergillosis
eng
uncontrolled
antifungal agents
eng
uncontrolled
invasive candidiasis
Medizin und Gesundheit
open_access
Medizinische Klinik und Poliklinik II
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/12134/044_Mousset_Annals_of_Hematology.pdf
18758
2016
eng
1435-1455
9
95
article
Infectious Diseases Working Party of the German Society for Hematology and Medical Oncology (AGIHO/DGHO) and the DAG-KBT (German Working Group for Blood and Marrow Transplantation)
1
2019-09-19
--
--
Infectious diseases in allogeneic haematopoietic stem cell transplantation: prevention and prophylaxis strategy guidelines 2016
Infectious complications after allogeneic haematopoietic stem cell transplantation (allo-HCT) remain a clinical challenge. This is a guideline provided by the AGIHO (Infectious Diseases Working Group) of the DGHO (German Society for Hematology and Medical Oncology). A core group of experts prepared a preliminary guideline, which was discussed, reviewed, and approved by the entire working group. The guideline provides clinical recommendations for the preventive management including prophylactic treatment of viral, bacterial, parasitic, and fungal diseases. The guideline focuses on antimicrobial agents but includes recommendations on the use of vaccinations. This is the updated version of the AGHIO guideline in the field of allogeneic haematopoietic stem cell transplantation utilizing methods according to evidence-based medicine criteria.
Annals of Hematology
10.1007/s00277-016-2711-1
urn:nbn:de:bvb:20-opus-187587
Annals of Hematology (2016) 95:9, 1435-1455. https://doi.org/10.1007/s00277-016-2711-1
false
true
CC BY: Creative-Commons-Lizenz: Namensnennung 4.0 International
Andrew J. Ullmann
Martin Schmidt-Hieber
Hartmut Bertz
Werner J. Heinz
Michael Kiehl
William Krüger
Sabine Mousset
Stefan Neuburger
Silke Neumann
Olaf Penack
Gerda Silling
Jörg Janne Vehreschild
Hermann Einsele
Georg Maschmeyer
eng
uncontrolled
Bone-marrow-transplantation
eng
uncontrolled
Pneumocystis-carinii-pneumonia
eng
uncontrolled
Influenzae type B
eng
uncontrolled
Respiratory syncytial virus
eng
uncontrolled
Infections
eng
uncontrolled
invasive fungal infections
eng
uncontrolled
Varicella-Zoster-Virus
eng
uncontrolled
Hepatitis B virus
eng
uncontrolled
Herpes simplex virus
eng
uncontrolled
Human immunodefiency virus
eng
uncontrolled
Low-dose acyclovir
eng
uncontrolled
Viral
eng
uncontrolled
Fungal
eng
uncontrolled
Bacteria
Medizin und Gesundheit
open_access
Medizinische Klinik und Poliklinik II
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/18758/Ullmann_AnnalsOfHematology_2016.pdf