16220
2018
eng
626
Supplement No. 1
59
conferenceobject
1
2018-05-27
--
--
Diagnostic Accuracy of Visual Assessment of an Initial DaT-Scan in Comparison to a Fully Automatic Semiquantitative Method
No abstract available.
Journal of Nuclear Medicine
0161-5505
http://jnm.snmjournals.org/content/59/supplement_1/626.abstract
urn:nbn:de:bvb:20-opus-162208
This research was originally published in JNM. Rudolf A. Werner, Charles Marcus, Sara Sheikhbahaei, Takahiro Higuchi, Lilja B. Solnes, Steven P. Rowe, Andreas K. Buck, Constantin Lapa, Mehrbod S. Javadi. Diagnostic Accuracy of Visual Assessment of an Initial DaT-Scan in Comparison to a Fully Automatic Semiquantitative Method. J Nucl Med. May 1, 2018; vol. 59 no. supplement 1:626. © SNMMI.
Johns Hopkins School of Medicine
701983
Journal of Nuclear Medicine May 1, 2018 vol. 59 no. supplement 1 626
Deutsches Urheberrecht
Rudolf A. Werner
Charles Marcus
Sara Sheikhbahaei
Takahiro Higuchi
Lilja B. Solnes
Steven P. Rowe
Andreas K. Buck
Constantin Lapa
Mehrbod S. Javadi
deu
swd
Parkinson-Krankheit
eng
uncontrolled
SPECT
eng
uncontrolled
Parkinson
eng
uncontrolled
Parkinson Disease
eng
uncontrolled
DaTscan
eng
uncontrolled
Ioflupane
eng
uncontrolled
molecular imaging
Medizin und Gesundheit
open_access
Klinik und Poliklinik für Nuklearmedizin
OpenAIRE
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/16220/Werner_Rudolf_Accuracy_DaT-Scan_JNM_accepted_version.pdf
16221
2018
eng
1646
Supplement No 1
59
conferenceobject
1
2018-05-27
--
--
The Impact of Ageing on Dopamine Transporter Imaging
No abstract available.
Journal of Nuclear Medicine
0161-5505
urn:nbn:de:bvb:20-opus-162213
http://jnm.snmjournals.org/content/59/supplement_1/1646.abstract
This research was originally published in JNM. Rudolf A. Werner, Charles Marcus, Sara Sheikhbahaei, Takahiro Higuchi, Lilja B. Solnes, Steven P. Rowe, Andreas K. Buck, Constantin Lapa, Mehrbod S. Javadi. The Impact of Ageing on Dopamine Transporter Imaging. J Nucl Med. May 1, 2018; vol. 59 no. supplement 1:1646. © SNMMI.
Johns Hopkins School of Medicine
701983
Journal of Nuclear Medicine May 1, 2018 vol. 59 no. supplement 1 1646
Deutsches Urheberrecht
Rudolf A. Werner
Charles Marcus
Sara Sheikhbahaei
Takahiro Higuchi
Lilja B. Solnes
Steven P. Rowe
Andreas K. Buck
Constantin Lapa
Mehrbod S. Javadi
deu
swd
Parkinson-Krankheit
eng
uncontrolled
Parkinson
eng
uncontrolled
Parkinson Disease
eng
uncontrolled
DaTscan
eng
uncontrolled
Ioflupane
eng
uncontrolled
SPECT
eng
uncontrolled
molecular imaging
eng
uncontrolled
ageing
Medizin und Gesundheit
open_access
Klinik und Poliklinik für Nuklearmedizin
OpenAIRE
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/16221/Werner_Rudolf_Ageing_DaTscan_JNM_accepted_version.pdf
16818
2018
eng
1
44
article
1
2018-09-12
--
--
Visual and Semiquantitative Accuracy in Clinical Baseline 123I-Ioflupane SPECT/CT Imaging
PURPOSE:
We aimed to (a) elucidate the concordance of visual assessment of an initial I-ioflupane scan by a human interpreter with comparison to results using a fully automatic semiquantitative method and (b) to assess the accuracy compared to follow-up (f/u) diagnosis established by movement disorder specialists.
METHODS:
An initial I-ioflupane scan was performed in 382 patients with clinically uncertain Parkinsonian syndrome. An experienced reader performed a visual evaluation of all scans independently. The findings of the visual read were compared with semiquantitative evaluation. In addition, available f/u clinical diagnosis (serving as a reference standard) was compared with results of the human read and the software.
RESULTS:
When comparing the semiquantitative method with the visual assessment, discordance could be found in 25 (6.5%) of 382 of the cases for the experienced reader (ĸ = 0.868). The human observer indicated region of interest misalignment as the main reason for discordance. With neurology f/u serving as reference, the results of the reader revealed a slightly higher accuracy rate (87.7%, ĸ = 0.75) compared to semiquantification (86.2%, ĸ = 0.719, P < 0.001, respectively). No significant difference in the diagnostic performance of the visual read versus software-based assessment was found.
CONCLUSIONS:
In comparison with a fully automatic semiquantitative method in I-ioflupane interpretation, human assessment obtained an almost perfect agreement rate. However, compared to clinical established diagnosis serving as a reference, visual read seemed to be slightly more accurate as a solely software-based quantitative assessment.
Clinical Nuclear Medicine
1536-0229
urn:nbn:de:bvb:20-opus-168181
Clinical Nuclear Medicine 2019, 44, 1, p 1–3 doi: 10.1097/RLU.0000000000002333
701983
false
true
CC BY-NC-ND: Creative-Commons-Lizenz: Namensnennung, Nicht kommerziell, Keine Bearbeitungen 4.0 International
Rudolf A. Werner
Charles Marcus
Sara Sheikhbahaei
Lilja B. Solnes
Jeffrey P. Leal
Yong Du
Steven P. Rowe
Takahiro Higuchi
Andreas K. Buck
Constantin Lapa
Mehrbod S. Javadi
deu
uncontrolled
Single-Photon-Emissions-Computertomographie
deu
swd
SPECT
eng
uncontrolled
Parkinson’s disease
eng
uncontrolled
Parkinsonism
eng
uncontrolled
DaTscan
eng
uncontrolled
123I-Ioflupane
eng
uncontrolled
SPECT
eng
uncontrolled
SPECT/CT
Medizin und Gesundheit
open_access
Klinik und Poliklinik für Nuklearmedizin
OpenAIRE
Universität Würzburg
https://opus.bibliothek.uni-wuerzburg.de/files/16818/Werner_Visual_and_Semiquantitative_Accuracy_Clinical_Nuclear_Medicine_2019.pdf