TY  - JOUR
A1  - Paponov, Ivan A.
A1  - Dindas , Julian
A1  - Król , Elżbieta
A1  - Friz, Tatyana
A1  - Budnyk, Vadym
A1  - Teale, William
A1  - Paponov, Martina
A1  - Hedrich , Rainer
A1  - Palme, Klaus
T1  - Auxin-Induced plasma membrane depolarization is regulated by Auxin transport and not by AUXIN BINDING PROTEIN1
JF  - Frontiers in Plant Science
N2  - Auxin is a molecule, which controls many aspects of plant development through both transcriptional and non-transcriptional signaling responses. AUXIN BINDING PROTEIN1 (ABP1) is a putative receptor for rapid non-transcriptional auxin-induced changes in plasma membrane depolarization and endocytosis rates. However, the mechanism of ABP1-mediated signaling is poorly understood. Here we show that membrane depolarization and endocytosis inhibition are ABP1-independent responses and that auxin-induced plasma membrane depolarization is instead dependent on the auxin influx carrier AUX1. AUX1 was itself not involved in the regulation of endocytosis. Auxin-dependent depolarization of the plasma membrane was also modulated by the auxin efflux carrier PIN2. These data establish a new connection between auxin transport and non-transcriptional auxin signaling.
KW  - auxin
KW  - ABP1
KW  - plasma membrane depolarization
KW  - AUX1
KW  - endocytosis
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-195914
SN  - 1664-462X
VL  - 9
ER  - 
TY  - JOUR
A1  - Naseem, Muhammad
A1  - Srivastava, Mugdha
A1  - Dandekar, Thomas
T1  - Stem-cell-triggered immunity safeguards cytokinin enriched plant shoot apexes from pathogen infection
JF  - Frontiers in Plant Science
N2  - Intricate mechanisms discriminate between friends and foes in plants. Plant organs deploy overlapping and distinct protection strategies. Despite vulnerability to a plethora of pathogens, the growing tips of plants grow bacteria free. The shoot apical meristem (SAM) is among three stem cells niches, a self-renewable reservoir for the future organogenesis of leaf, stem, and flowers. How plants safeguard this high value growth target from infections was not known until now. Recent reports find the stem cell secreted 12-amino acid peptide CLV3p (CLAVATA3 peptide) is perceived by FLS2 (FLAGELLIN SENSING 2) receptor and activates the transcription of immunity and defense marker genes. No infection in the SAM of wild type plants and bacterial infection in clv3 and fls2 mutants illustrate this natural protection against infections. Cytokinins (CKs) are enriched in the SAM and regulate meristem activities by their involvement in stem cell signaling networks. Auxin mediates plant susceptibility to pathogen infections while CKs boost plant immunity. Here, in addition to the stem-cell-triggered immunity we also highlight a potential link between CK signaling and CLV3p mediated immune response in the SAM.
KW  - auxin
KW  - stem cell niche
KW  - FLS2 receptor
KW  - CLAVATA3
KW  - cytokinins
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-118247
SN  - 1664-462X
VL  - 5
ER  -