TY  - JOUR
A1  - Heinsen, Helmut
A1  - Heinsen, Y. L.
T1  - Cerebellar capillaries: qualitative and quantitative observations in young and senile rats
N2  - Ultrastructural changes including reduced electron density, reduction in polysemes and cisternae of rough endoplasmic reticulum occur in the cytoplasrn of endothelial cells and pericytes in the cerebellar cortex of senile virgin female Han: WIST-rats in cornparison to 3-month old virgin rats. Processes of pericytes cover less of the capillary surface in the cerebellar cortex of senile rats; moreover, arithmetic and harmonic mean thickness of the endothelium and relative volume of mitochondria in endothelial cells and pericytes are reduced, w hereas the luminal diameter of the capillaries, harmonic and arithmetic mean thickness of pericytes and their processes and of the basal laminae between endothelial cells and astrocytes (abbreviated BAL 1), pericytes and astrocytes (BAL 2) and endothelial cells and pericytes (BAL 3) increase. The increase in harmonic mean thickness of the basal laminae is statistically significant (α<=0.05) and compensates for a decrease in thickness of capillary endothelium. Consequently, the total barrier mass and thickness of cerebellar cortical capillaries in senile animals is higher than in young individuals.
KW  - Medizin
KW  - Capillaries
KW  - Blood-brain barrier
KW  - Quantitative anatomy
KW  - Cerebellar cortex
KW  - Senile rats
Y1  - 1983
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59924
ER  - 
TY  - JOUR
A1  - Heinsen, Helmut
A1  - Heinsen, Y. L.
T1  - Quantitative studies on regional differences in Purkinje cell dendritic spines and parallel fiber synaptic density
N2  - No abstact available
KW  - Medizin
KW  - Cerebellar cortex
KW  - Albino rats
KW  - Quantitative anatomy
KW  - Purkinje cells
KW  - Spines
KW  - Parallel fiber synapses
KW  - Regional differences
Y1  - 1983
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59917
ER  - 
TY  - JOUR
A1  - Heinsen, Helmut
T1  - Lipofuscin in the cerebellar cortex of albino rats: an electron microscopic study
N2  - The ultrastructure of autofluorescent, PAS-positive lipofuscin in Purkinje, granule, Golgi epithelial, basket and stellate, microglial and perivascular cells in the cerebellar cortex of senescent rats is described. The membrane- bounded pigment is composed ofthree elements: 1) electron-lucent homogeneaus droplets, 2) a granular matrix and 3) intensely osmiophilic patches. The proportians ofthese three components vary between cell types and one can grossly differentiate a neuronal and a gliallipofuscin. The lipofuscin granules of stellate and perivscular cells are different from lipofuscin of other cerebellar neurons and glia. lt can be concluded from these morphological observations that each cerebellar cell type has its distinct lipofuscin.
KW  - Medizin
KW  - Lipofuscin
KW  - Cerebellar cortex
KW  - Ultrastructure
KW  - Senescent rat
Y1  - 1979
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59891
ER  -