TY  - JOUR
A1  - El-Hossary, Ebaa M.
A1  - Abdel-Halim, Mohammad
A1  - Ibrahim, Eslam S.
A1  - Pimentel-Elardo, Sheila Marie
A1  - Nodwell, Justin R.
A1  - Handoussa, Heba
A1  - Abdelwahab, Miada F.
A1  - Holzgrabe, Ulrike
A1  - Abdelmohsen, Usama Ramadan
T1  - Natural Products Repertoire of the Red Sea
JF  - Marine Drugs
N2  - Marine natural products have achieved great success as an important source of new lead compounds for drug discovery. The Red Sea provides enormous diversity on the biological scale in all domains of life including micro- and macro-organisms. In this review, which covers the literature to the end of 2019, we summarize the diversity of bioactive secondary metabolites derived from Red Sea micro- and macro-organisms, and discuss their biological potential whenever applicable. Moreover, the diversity of the Red Sea organisms is highlighted as well as their genomic potential. This review is a comprehensive study that compares the natural products recovered from the Red Sea in terms of ecological role and pharmacological activities.
KW  - Red Sea
KW  - marine natural products
KW  - marine organisms
KW  - biodiversity
KW  - marine metagenomics
KW  - bioactivity
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-213110
SN  - 1660-3397
VL  - 18
IS  - 9
ER  -