TY - JOUR A1 - Ameri, Pietro A1 - Schiattarella, Gabriele Giacomo A1 - Crotti, Lia A1 - Torchio, Margherita A1 - Bertero, Edoardo A1 - Rodolico, Daniele A1 - Forte, Maurizio A1 - Di Mauro, Vittoria A1 - Paolillo, Roberta A1 - Chimenti, Cristina A1 - Torella, Daniele A1 - Catalucci, Daniele A1 - Sciarretta, Sebastiano A1 - Basso, Cristina A1 - Indolfi, Ciro A1 - Perrino, Cinzia T1 - Novel basic science insights to improve the management of heart failure: Review of the working group on cellular and molecular biology of the heart of the Italian Society of Cardiology JF - International Journal of Molecular Sciences N2 - Despite important advances in diagnosis and treatment, heart failure (HF) remains a syndrome with substantial morbidity and dismal prognosis. Although implementation and optimization of existing technologies and drugs may lead to better management of HF, new or alternative strategies are desirable. In this regard, basic science is expected to give fundamental inputs, by expanding the knowledge of the pathways underlying HF development and progression, identifying approaches that may improve HF detection and prognostic stratification, and finding novel treatments. Here, we discuss recent basic science insights that encompass major areas of translational research in HF and have high potential clinical impact. KW - heart failure KW - basic KW - translational KW - research KW - mechanisms Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-285085 SN - 1422-0067 VL - 21 IS - 4 ER -