TY  - CHAP
A1  - Rethwilm, Axel
A1  - Baunach, Gerald
A1  - Mori, Kazuyasu
A1  - ter Meulen, Volker
T1  - Transactivation of HIV by human spumaretrovirus
N2  - To study the activation of HIV by human spumaretrovirus (HSRV) the long terminal repeats (LTRs) of HSRV, HIVl and HIV2 were examined with respect to their ability to function as transcriptional promoters in virus infected and uninfected cells. Transient transfections using plasmids in which the L TRs of the three viruses were coupled to the bacterial chloramphenicol acetyltransferase (CA T) gene revealed (i) the level of cat gene expression directed by the HSRV LTR was markedly increased in HSRV infected cells compared to uninfected cells, (ii) cat gene expression driven by the HIV1 LTR, but not by the HIV2 LTR could be enhanced upon HSRV infection, whereas (iii) neither in HIV1 nor in HIV2 infected cells an effect on HSRV LTR driven cat geneexpression was detected.
KW  - HIV
Y1  - 1990
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86436
ER  - 
TY  - CHAP
A1  - Mori, Kazuyasu
A1  - Rethwilm, Axel
A1  - Schwinn, Andreas
A1  - Horak, Ivan
T1  - Replication of human immunodeficiency virus type 1 in human t-cells expressing antisense RNA
N2  - No abstract available.
KW  - HIV
Y1  - 1990
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86426
ER  - 
TY  - JOUR
A1  - Rethwilm, Axel
A1  - Mori, Kazuyasu
A1  - Maurer, Bernd
A1  - ter Meulen, Volker
T1  - Transacting transcriptional activation of human spumaretrovirus LTR in infected cells
N2  - The long terminal repeat (LTR) of the human spumaretrovirus (HSRV) was examined with respect to its ability to function as transcriptional promotor in virus-infected and uninfected cells. Transient transfections using a plasmid in which the 3' L TR of HSRV was coupled to the bacterial chloramphenicol cetyltransferase (cat) gene revealed that the Ievei of HSRV LTR-directed cat gene expression was markedly increased in HSRV-infected cells compared to uninfected cells. Northern blot analysis of cat mRNA from transfected cultures suggests that transactivation of HSRVdirected gene expression occurs at the transcriptionallevel.
KW  - Virologie
Y1  - 1990
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61488
ER  -