TY  - JOUR
A1  - Fathy, Moustafa
A1  - Saad Eldin, Sahar M.
A1  - Naseem, Muhammad
A1  - Dandekar, Thomas
A1  - Othman, Eman M.
T1  - Cytokinins: wide-spread signaling hormones from plants to humans with high medical potential
JF  - Nutrients
N2  - Nature is a rich source of biologically active novel compounds. Sixty years ago, the plant hormones cytokinins were first discovered. These play a major role in cell division and cell differentiation. They affect organogenesis in plant tissue cultures and contribute to many other physiological and developmental processes in plants. Consequently, the effect of cytokinins on mammalian cells has caught the attention of researchers. Many reports on the contribution and potential of cytokinins in the therapy of different human diseases and pathophysiological conditions have been published and are reviewed here. We compare cytokinin effects and pathways in plants and mammalian systems and highlight the most important biological activities. We present the strong profile of the biological actions of cytokinins and their possible therapeutic applications.
KW  - cytokinins
KW  - phytohormones
KW  - biological activities
KW  - plant system
KW  - mammalian system
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-271017
SN  - 2072-6643
VL  - 14
IS  - 7
ER  -