TY  - JOUR
A1  - Luber, Verena
A1  - Lutz, Mathias
A1  - Abele-Horn, Marianne
A1  - Einsele, Hermann
A1  - Grigoleit, Götz Ulrich
A1  - Mielke, Stephan
T1  - Excretion of Ascaris lumbricoides following reduced‐intensity allogeneic hematopoietic stem cell transplantation and consecutive treatment with mebendazole
JF  - Transplant Infectious Disease
N2  - Here, we present the unique case of a 51‐year‐old German patient with multiple myeloma excreting Ascaris lumbricoides in his stool five weeks after allogeneic hematopoietic stem cell transplantation. Stool analysis remained negative for the presence of eggs, and there was no eosinophilia in the peripheral blood at any time around stem cell transplantation. The patient was commenced on a three‐day treatment with mebendazole, which was well tolerated. No serious interactions with the concomitant post‐transplant medication or negative effects on the hematopoiesis were observed, and the myeloma still is in complete remission. To our knowledge, this is the first report on excretion of A lumbricoides in the context of allogeneic stem cell transplantation. The case is remarkable with view to the fact that the parasite has supposedly survived all courses of myeloma treatment including autologous and allogeneic conditioning. Parasitosis with A lumbricoides has a worldwide prevalence of about a billion and is extremely rare in northern Europe. Possibly the patient got infected during a trip to Egypt years before multiple myeloma was diagnosed.
KW  - sirolimus
KW  - mycophenolic acid
KW  - multiple myeloma
KW  - mebendazole
KW  - hematopoietic stem cell transplantation
KW  - Ascaris lumbricoides
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-219608
SN  - 1399-3062
VL  - 22
IS  - 1
ER  -