TY  - JOUR
A1  - Garcia-Larsen, Vanessa
A1  - Arthur, Rhonda
A1  - Potts, James F.
A1  - Howarth, Peter H.
A1  - Ahlström, Matti
A1  - Haahtela, Tari
A1  - Loureiro, Carlos
A1  - Bom, Ana Todo
A1  - Brożek, Grzegorz
A1  - Makowska, Joanna
A1  - Kowalski, Marek L.
A1  - Thilsing, Trine
A1  - Keil, Thomas
A1  - Matricardi, Paolo M.
A1  - Torén, Kjell
A1  - van Zele, Thibaut
A1  - Bachert, Claus
A1  - Rymarczyk, Barbara
A1  - Janson, Christer
A1  - Forsberg, Bertil
A1  - Niżankowska-Mogilnicka, Ewa
A1  - Burney, Peter G. J.
T1  - Is fruit and vegetable intake associated with asthma or chronic rhino-sinusitis in European adults? Results from the Global Allergy and Asthma Network of Excellence (GA\(^2\)LEN) Survey
JF  - Clinical and Translational Allergy
N2  - Background: Fruits and vegetables are rich in compounds with proposed antioxidant, anti-allergic and anti-inflammatory properties, which could contribute to reduce the prevalence of asthma and allergic diseases.
Objective: We investigated the association between asthma, and chronic rhino-sinusitis (CRS) with intake of fruits and vegetables in European adults.
Methods: A stratified random sample was drawn from the Global Allergy and Asthma Network of Excellence (GA\(^2\)LEN) screening survey, in which 55,000 adults aged 15–75 answered a questionnaire on respiratory symptoms. Asthma score (derived from self-reported asthma symptoms) and CRS were the outcomes of interest. Dietary intake of 22 subgroups of fruits and vegetables was ascertained using the internationally validated GA\(^2\)LEN Food Frequency Questionnaire. Adjusted associations were examined with negative binomial and multiple regressions. Simes procedure was used to control for multiple testing.
Results: A total of 3206 individuals had valid data on asthma and dietary exposures of interest. 22.8% reported having at least 1 asthma symptom (asthma score ≥1), whilst 19.5% had CRS. After adjustment for potential confounders, asthma score was negatively associated with intake of dried fruits (β-coefficient −2.34; 95% confidence interval [CI] −4.09, −0.59), whilst CRS was statistically negatively associated with total intake of fruits (OR 0.73; 95% CI 0.55, 0.97). Conversely, a positive association was observed between asthma score and alliums vegetables (adjusted β-coefficient 0.23; 95% CI 0.06, 0.40). None of these associations remained statistically significant after controlling for multiple testing.
Conclusion and clinical relevance: There was no consistent evidence for an association of asthma or CRS with fruit and vegetable intake in this representative sample of European adults.
KW  - Fruits
KW  - Vegetables
KW  - Asthma
KW  - Chronic rhino‑sinusitis
KW  - Adults
KW  - Europe
KW  - Meta‑analysis
KW  - GA\(^2\)LEN
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-180887
VL  - 7
ER  - 
TY  - THES
A1  - Mader, Kathrin
T1  - Neuronale Korrelate der Handlungsevaluation bei erwachsenen Patienten mit der Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung
T1  - Neural correlates of performance monitoring in adult patients with Attention Deficit Hyperactivitiy Disorder (ADHD)
N2  - EEG-Studie mit 34 erwachsenen ADHS-Patienten und 34 Kontrollpersonen mit einem modifizierten Eriksen-Flanker-Test. Dabei zeigten sich bei den ADHS Patienten verglichen mit der Kontrollgruppe verlängerte Reaktionszeiten, aber eine normale Fehleranzahl und ein normales post error slowing. Die ERN und die Pe waren vermindert. Dies weist auf Defizite in der Handlungsüberwachung bei erwachsenen ADHS-Patienten hin.
N2  - EEG-Study with 34 adult patients with ADHD and 34 healthy controls with a modified Eriksen flanker task. We found slower reaction times but a normal number of mistakes and a normal post error slowing in the ADHD group. The ERN and the Pe were reduced. This leads to the conclusion of deficient error processing in adult ADHD patients.
KW  - Aufmerksamkeits-Defizit-Syndrom
KW  - Erwachsener
KW  - ERN
KW  - Pe
KW  - post error slowing
KW  - ADHD
KW  - Adults
KW  - ERN
KW  - Pe
KW  - post error slowing
Y1  - 2010
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-48993
ER  -