TY  - JOUR
A1  - Föcker, Manuel
A1  - Timmesfeld, Nina
A1  - Bühlmeier, Judith
A1  - Zwanziger, Denise
A1  - Führer, Dagmar
A1  - Grasemann, Corinna
A1  - Ehrlich, Stefan
A1  - Egberts, Karin
A1  - Fleischhaker, Christian
A1  - Wewetzer, Christoph
A1  - Wessing, Ida
A1  - Seitz, Jochen
A1  - Herpertz-Dahlmann, Beate
A1  - Hebebrand, Johannes
A1  - Libuda, Lars
T1  - Vitamin D level trajectories of adolescent patients with anorexia nervosa at inpatient admission, during treatment, and at one year follow up: association with depressive symptoms
JF  - Nutrients
N2  - (1) Background: Evidence has accumulated that patients with anorexia nervosa (AN) are at higher risk for vitamin D deficiency than healthy controls. In epidemiologic studies, low 25(OH) vitamin D (25(OH)D) levels were associated with depression. This study analyzed the relationship between 25(OH)D serum levels in adolescent patients and AN and depressive symptoms over the course of treatment. (2) Methods: 25(OH)D levels and depressive symptoms were analyzed in 93 adolescent (in-)patients with AN from the Anorexia Nervosa Day patient versus Inpatient (ANDI) multicenter trial at clinic admission, discharge, and 1 year follow up. Mixed regression models were used to analyze the relationship between 25(OH)D levels and depressive symptoms assessed by the Beck Depression Inventory (BDI-II). (3) Results: Although mean 25(OH)D levels constantly remained in recommended ranges (≥50 nmol/L) during AN treatment, levels decreased from (in)patient admission to 1 year follow up. Levels of 25(OH)D were neither cross-sectionally, prospectively, nor longitudinally associated with the BDI-II score. (4) Conclusions: This study did not confirm that 25(OH)D levels are associated with depressive symptoms in patients with AN. However, increasing risks of vitamin D deficiency over the course of AN treatment indicate that clinicians should monitor 25(OH)D levels.
KW  - vitamin D
KW  - supplements
KW  - anorexia nervosa
KW  - depressive symptoms
KW  - adolescents
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-242662
SN  - 2072-6643
VL  - 13
IS  - 7
ER  -