TY  - JOUR
A1  - Neubert, Sven
A1  - Schlecht, Sina
A1  - Meng, Karin
A1  - Rabe, Antonia
A1  - Jentschke, Elisabeth
T1  - Effects of a video sequence based intervention on anxiety, fatigue and depression in cancer patients: results of a randomized controlled trial
JF  - Integrative Cancer Therapies
N2  - Background:
Cancer patients often suffer from psychological symptoms and need psychological support. Especially during the COVID-19 pandemic, eHealth interventions might be helpful to overcome the obstacles of the pandemic. This study evaluates the effectiveness of a video sequence-based eHealth intervention on anxiety, fatigue, and depression in cancer patients.

Methods:
Patients (N = 157) with different tumor entities were randomly assigned to the video intervention group (IG) and the waiting control group (CG). Patients in the IG received a video intervention comprising 8 video sequences over 4 weeks. The videos included psychoeducation on distress and psychological symptoms, Acceptance and Commitment Therapy elements, and Yoga and Qigong exercises. Patients’ anxiety and fear of progression (primary outcomes) and secondary outcomes were assessed before randomization (T1) and after the end of the intervention for IG or the waiting period for CG (T2) using self-reported questionnaires (GAD-7, PA-F-KF, EORTC QLQ-FA12, PHQ-8).

Results:
Patients of the IG showed no significant improvement in anxiety (GAD-7; P = .75), fear of progression (FoP-Q-SF; P = .29), fatigue (EORTC QLQ-FA12; P = .72), and depression (PHQ-8; P = .95) compared to patients in the waiting CG. However, symptoms of anxiety, fatigue, and depression decreased in both groups. Exploratory subgroup analysis regarding sex, therapy status, therapy goal, and tumor entity showed no effects. Overall, the intervention had a high level of acceptance.

Conclusions:
The video intervention was ineffective in reducing the psychological burden compared to a waiting CG. The findings support prior observations of the value of therapeutic guidance and promoting self-management for improving patients’ psychological burdens. Further studies are required to evaluate the effectiveness of psycho-oncological eHealth delivered through video sequences.
KW  - eHealth
KW  - psycho-oncology
KW  - complementary medicine
KW  - psychoeducation
KW  - mind-body-intervention
KW  - anxiety
KW  - depression
KW  - fatigue
KW  - oncology
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-304581
SN  - 1552-695X
VL  - 22
ER  - 
TY  - JOUR
A1  - Ferianec, Vladimír
A1  - Fülöp, Matej
A1  - Ježovičová, Miriam
A1  - Radošinská, Jana
A1  - Husseinová, Marta
A1  - Feriancová, Michaela
A1  - Radošinská, Dominika
A1  - Barančík, Miroslav
A1  - Muchová, Jana
A1  - Hȍgger, Petra
A1  - Ďuračková, Zdeňka
T1  - The oak−wood extract Robuvit\(^®\) improves recovery and oxidative stress after hysterectomy: a randomized, double-blind, placebo-controlled pilot study
JF  - Nutrients
N2  - Hysterectomy has a variety of medical indications and improves pre-operative symptoms but might compromise the quality of life during recovery due to symptoms such as fatigue, headache, nausea, depression, or pain. The aim of the present study was to determine the effect of a standardized extract from French oak wood (Quercus robur) containing at least 40% polyphenols of the ellagitannins class, Robuvit\(^®\), on convalescence and oxidative stress of women after hysterectomy. Recovery status was monitored with the SF-36 questionnaire. The supplementation with Robuvit\(^®\) (300 mg/day) during 4 weeks significantly improved general and mental health, while under placebo some items significantly deteriorated. Oxidative stress and enhancement of MMP–9 activity was significantly reduced by Robuvit\(^®\) versus placebo. After 8 weeks of intervention, the patients’ condition improved independently of the intervention. Our results suggest that the use of Robuvit\(^®\) as a natural supplement relieves post-operative symptoms of patients after hysterectomy and reduces oxidative stress. The study was registered with ID ISRCTN 11457040 (13/09/2019).
KW  - hysterectomy
KW  - Robuvit\(^®\)
KW  - oak wood extract
KW  - post-operative recovery
KW  - oxidative stress
KW  - matrix metalloproteinases
KW  - complementary medicine
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-203265
SN  - 2072-6643
VL  - 12
IS  - 4
ER  -