TY  - JOUR
A1  - Nguemeni, Carine
A1  - Stiehl, Annika
A1  - Hiew, Shawn
A1  - Zeller, Daniel
T1  - No Impact of Cerebellar Anodal Transcranial Direct Current Stimulation at Three Different Timings on Motor Learning in a Sequential Finger-Tapping Task
JF  - Frontiers in Human Neuroscience
N2  - Background: Recently, attention has grown toward cerebellar neuromodulation in motor learning using transcranial direct current stimulation (tDCS). An important point of discussion regarding this modulation is the optimal timing of tDCS, as this parameter could significantly influence the outcome. Hence, this study aimed to investigate the effects of the timing of cerebellar anodal tDCS (ca-tDCS) on motor learning using a sequential finger-tapping task (FTT).
Methods: One hundred and twenty two healthy young, right-handed subjects (96 females) were randomized into four groups (During\(_{sham}\), Before, During\(_{real}\), After). They performed 2 days of FTT with their non-dominant hand on a custom keyboard. The task consisted of 40 s of typing followed by 20 s rest. Each participant received ca-tDCS (2 mA, sponge electrodes of 25 cm\(^{2}\), 20 min) at the appropriate timing and performed 20 trials on the first day (T1, 20 min). On the following day, only 10 trials of FTT were performed without tDCS (T2, 10 min). Motor skill performance and retention were assessed.
Results: All participants showed a time-dependent increase in learning. Motor performance was not different between groups at the end of T1 (p = 0.59). ca-tDCS did not facilitate the retention of the motor skill in the FTT at T2 (p = 0.27). Thus, our findings indicate an absence of the effect of ca-tDCS on motor performance or retention of the FTT independently from the timing of stimulation.
Conclusion: The present results suggest that the outcome of ca-tDCS is highly dependent on the task and stimulation parameters. Future studies need to establish a clear basis for the successful and reproducible clinical application of ca-tDCS.
KW  - cerebellar tDCS
KW  - finger-tapping task
KW  - timing
KW  - motor learning
KW  - task retention
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-225477
SN  - 1662-5161
VL  - 15
ER  - 
TY  - THES
A1  - Lenhard, Alexandra
T1  - Intra- and intermanual transfer of adaptation to unnoticed virtual displacement under terminal and continuous visual feedback
N2  - Versuchspersonen trainierten mit der rechten Hand Zielbewegungen zu verschiedenen Zielen unter terminalem oder kontinuierlichem visuellem Feedback. Für eines der Ziele wurde die visuelle Rückmeldung so manipuliert, dass Bewegungen zu diesem Ziel kürzer wirkten, als sie tatsächlich waren. Nach dem Training sollten die gleichen Ziele sowohl mit der trainierten rechten als auch mit der untrainierten linken Hand erreicht werden. Bewegungen der rechten Hand passten sich an die unbemerkte visuelle Transformation an. Die Adaptation war unter kontinuierlichem Feedback schwächer als unter terminalem. Außerdem generalisierte die Adapation nur unter terminalem, aber nicht unter kontinuierlichem Feedback, auf andere Zielbewegungen in die gleiche Richtung, aber nicht auf Zielbewegungen in die entgegengesetzte Richtung. Bewegungen der untrainierten linken Hand zeigten qualitativ die gleichen adaptationsbedingten Veränderungen wie Bewegungen der rechten Hand. Die Ergebnisse sprechen für die Annahme, dass beim Training der rechten Hand eine effektorunabhängige räumliche Repräsentation verändert wird, auf die bei der Steuerung beider Hände zurückgegriffen wird.
N2  - Participants trained aiming movements of the right hand to several targets with a prism-like virtual displacement of the location of one of the targets, receiving either terminal or continuous visual feedback. After training, the same targets were to be reached with the untrained left hand under manipulated feedback conditions. The right hand movements continuously adapted to the unnoticed visual displacement, significantly less with continuous than with terminal feedback. Under terminal but not under continuous feedback the adaptation to the manipulated target generalized to targets in the same horizontal direction but not to targets in the opposite direction. Finally, the movements of the untrained left hand showed the same qualitative changes to the targets as the movements of the trained right hand. The data are in line with the notion that the adaptation of the right hand movements is mainly based on a re-interpretation of target locations on which movement control of both hands draws.
KW  - Motorisches Lernen
KW  - Bewegungssteuerung
KW  - Rückmeldung
KW  - Transfer
KW  - visuomotorische Transformation
KW  - intermanueller Transfer
KW  - Zielbewegungen
KW  - motor learning
KW  - intermanual transfer
KW  - aiming
KW  - visuomotor transformation
KW  - feedback
Y1  - 2002
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-23889
ER  -