TY - JOUR A1 - Wirbelauer, J. A1 - Hof, H. A1 - Hacker, Jörg T1 - Die Wirkung von Desacetylcefotaxin, einem Metaboliten von Cefotaxim, in vitro und auf die experimentelle Infektion mit Escherichia coli T1 - Activity of Desacetylcefotaxime, a Metabolite of Cefotaxime, In Vitro and in a Model of Experimental Infection with Escherichia coli N2 - Die MHK-Werte von Desacetylcefotaxim gegen verschiedene, z. T. ampicillinresistente Stämme von Escherichia coH, die mit Hilfe einer Agardilutionsmethode erhoben wurden, waren höher als die von Cefotaxim und Ceftriaxon, jedoch niedriger als die von Cefoxitin. In einem Modell der systemischen Infektion der Maus mit einem plasmidtragenden, betalactamaseproduzierenden Stamm von E. coli führte die Therapie mit Desacetylcefotaxim zu einer starken Reduktion der Keime pro Leber. Im Vergleich zur Therapie mit Cefotaxim trat die protektive Wirkung aber verlangsamt ein. Desacetylcefotaxim ist also kein unnützes Abbauprodukt von Cefotaxim. N2 - The MIC values of desacetylcefotaxime, as determined by an agar dilution method, for several strains of Escherichia coli largely resistant to ampicillin were considerably higher than those of cefotaxime or ceftriaxone respectively. The values were, however, definitely lower than those of cefoxitin. In a mouse model of a systemic infection with a plasmid-bearing, j3-lactamase producing strain of E. coli the therapeutic potency of ampicillin, cefotaxime and desacetylcefotaxime was determined by counting the bacterial numbers per liver at days 1,3 and 7 after subcutaneous infection with about 103 viable bacteria. Desacety1cefotaxime was able to redure thc bacterial load considerably, though with a delay in comparison to cefotaxime. Y1 - 1988 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-40348 ER - TY - JOUR A1 - Wrobel, D. A1 - Tacke, Reinhold A1 - Wannagat, U. A1 - Harder, U. T1 - Sila-Analoga tertiärer Carbinole mit Duftwirkung T1 - Sila Analogues of Tertiary Carbinols as Perfumes N2 - Es wurden Silanale RR'R"SiOH 7 dargestellt, die Carbinolen RR'R"COH 1 (R = CH\(_3\) , R' = CH\(_3\) , CH = CH\(_2\) , C\(_2\)H\(_5\) , R" = CH\(_2\)C\(_6\)H\(_5\) , CH\(_2\)CH\(_2\)C\(_6\)H\(_5\)) mit starker Duftwirkung im Bereich blumiger Noten (Maiglöckchen-Hyazinthe-Rose) analog waren. Ihr Syntheseweg verläuft über die Reaktionsschritte (3) mit teilweise bisher unbekannten Zwischenstufen 6. Die Sila-Riechstoffe 7 sind in Intensität und Duftbereich den Carbinolen 1 ähnlich, doch ist allgemein eine Verschiebung der Duftnote von Maiglöckchen zu Hyazinthe zu beobachten. N2 - Silanals RR'R"SiOH 7 which areanalog to carbinols 1 with strong odour in the region of flowery notes (lily of the valley-hyacinth-rose) were prepared via reaction steps (3) and partially unknown intermediates 6. Sila perfumes 7 are similar in intensity and spectrum of odour to 1 but a shift from lily of the valley towards hyacinth notes is generally observed. KW - Anorganische Chemie Y1 - 1982 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63705 ER - TY - JOUR A1 - Wörsdörfer, Anna Isabell T1 - Vom ‘bon sauvage’ zum französischen Ritter par excellence. Die ‘Matière de Bretagne’ als Streitobjekt konkurrierender Erinnerungskulturen in Jean-Pierre Claris de Florians Mittelalternovelle Bliombéris (1784). JF - promptus - Würzburger Beiträge zur Romanistik N2 - While French Enlightenment seems philosophically dominated by a pejorative idea of the medieval past as the ‘Dark Ages’, this is only one conception among others. This article focuses on a different, a positive, representation of the Middle Ages in eighteenth-century literature, analyzing the chivalric novella Bliombéris (1784) by Jean-Pierre Claris de Florian. On the one hand, the eponymous hero is considered a ‘noble savage’ who develops into an ideal knight by education and successful learning – two central ideas of the Enlightenment period. On the other hand, the study shows how the medieval topic of the Matière de Bretagne, exclusively required by English literature for a long time, is finally regained by the French and is reintegrated into their national memory. KW - Bliombéris Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-139518 SN - 2510-2613 VL - 1 ER - TY - JOUR A1 - Wörsdörfer, Anna Isabell T1 - Hexen Revival. Produktive Bécquer Rezeption und Gattungsspezifik in Jugendbuch und TV Serie BT - Dietmar Rieger zum 77. Geburtstag JF - promptus - Würzburger Beiträge zur Romanistik N2 - This article exemplifies Gunter Grimm’s concept of productive reception by analyzing César Fernández García’s young adult novel La última bruja de Trasmoz (2009) and the episode Tiempo de hechizos (2017) of the TV series El ministerio del tiempo as two modern works which artistically and creatively deal with Gustavo Adolfo Bécquer’s Cartas desde mi celda (1864). The study is based on the core assumption that the choice of genre greatly influences the treatment of motives such as the perception of nature and the idea of dreams, as well as the image of the witch. While Bécquer’s letters, which focus on the rural people’s superstition, present the witch of Aragonese folklore, the modern examples portray two of her fantastic counterparts: the novel depicts its magical protagonist as an evil supernatural being, whereas the TV episode of the science fiction series shows the witch as a time traveller and a victim. KW - Cartas desde mi celda KW - Fantasy KW - Gustavo Adolfo Bécquer KW - Hexe KW - produktive Rezeption Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-221900 SN - 2364-6705 VL - 5 ER - TY - JOUR A1 - Zhuber-Okrog, Karen T1 - "Der Spaß und das Interesse diese Sprache zu lernen überwiegt" - Erfahrungen aus dem Selbstlernprojekt "Erste Schritte Russisch / Erste Schritte Arabisch" N2 - In diesem Artikel wird ein betreutes Selbstlernprojekt für Sprachanfänger in Arabisch und Russisch beschrieben. Ziel war der eigenverantwortliche Spracherwerb mit Hilfe von Lernsoftware in Verbindung mit persönlicher tutorieller Betreuung von Muttersprachlern. Ein besonderes Augenmerk lag dabei auf der Bewusstmachung des Lernprozesses und der Aufrechterhaltung der Lernmotivation. N2 - This paper describes an autonomous language learning project, for beginners of Russian or Arabic who were supposed to work with language learning software, accompanied by student native speakers as tutors. There was a special focus on the students’ understanding of their own learning process and maintaining their levels of motivation. KW - Neue Medien KW - Fremdsprachenlernen KW - Fremdsprachenunterricht KW - Lernautonomie KW - Sprachtutoren KW - Sprachsoftware KW - Learning autonomy KW - new technologies KW - language tutors KW - language programs Y1 - 2010 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-49839 ER - TY - JOUR A1 - Ziegler, Robert Hugo T1 - Die Rückkehr des Realen JF - Deutsche Zeitschrift für Philosophie N2 - We are witnessing a return of the real which philosophy seems illequipped to handle. I argue (1) that this return of the real must be read as a rejection of those philosophical tendencies which were prevalent in the past decades and which I call philosophies of mediation: They supplanted all references to something real by the sole reference to those processes in which reality was supposed to be given or shaped (in interpretations, linguistic structures, historical or social conditions, media…). The current urgency of the question of the real indicates that those philosophies have lost credibility. On the other hand (2), the contemporary attempts to resuscitate philosophical realism cannot be considered satisfactory either. It is curiously the real itself they fail to fully appreciate. All in all (3), the return of the real has to be interpreted as the effect of an event that has little to do with philosophy, namely the return of politics. KW - realism KW - nature KW - politics KW - media KW - postmodernism Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-217771 SN - 2192-1482 SN - 0012-1045 N1 - Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. VL - 68 IS - 4 SP - 611 EP - 626 ER - TY - JOUR A1 - Zielinski, Werner A1 - Schneider, Wolfgang T1 - Diagnostische Möglichkeiten bei Lese- und Rechtschreibschwierigkeiten - Folgerungen aus der Forschung N2 - No abstract available. KW - Rechtschreibschwäche KW - Lesestörung KW - Diagnose Y1 - 1986 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-87325 ER - TY - JOUR A1 - Zilch, H. A1 - Tacke, Reinhold T1 - Fluorid-induzierte Fragmentierung von Acetyldimethylphenylsilan N2 - Acetyldimethylphenylsilane (2) reacts with TBAF · 3H\(_2\)O in THF and with KF in DMSO/H\(_2\)0, respectively, to give [(CH\(_3\) )\(_2\)SiO]\(_x\) and 1-Phenylethanol (3) which can be isolated with a nearly quantitative yield. The way 2 reacts with F\(^-\) contrasts with that of some aroyl- and heteroaroyltrimethylsilanes, described in the literature. A reaction mechanism is discussed which involves among others a 1 ,2-phenyl shift and a Brook rearrangement. N2 - Acetyldimethylphenylsilan (2) reagiert bei Raumtemperatur mit TBAF · 3H\(_2\)O in THF bzw. mit KF in DMSO/H\(_2\)O zu [(CH\(_3\))\(_2\)SiO]\(_x\) und 1-Phenylethanol (3), welches mit praktisch quantitativer Ausbeute isoliert werden kann. Dieses Reaktionsverhalten von 2 gegenüber F\(^-\) weicht drastisch ab von dem in der Literatur beschriebenen Verhalten einiger Aroyl- und Heteroaroyltrimethylsilane. Ein Reaktionsmcchanismus, der u.a. eine 1,2-Phenylverschiebung und eine BrookUmlagerung beinhaltet, wird zur Diskussion gestellt. KW - Anorganische Chemie Y1 - 1986 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63802 ER - TY - JOUR A1 - Zimmermann, U. A1 - Stopper, Helga T1 - Elektrofusion und Elektropermeabilisierung von Zellen N2 - No abstract available. KW - Elektrofusion KW - Elektroporation KW - Zelle Y1 - 1986 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-86865 ER - TY - JOUR T1 - Search for supersymmetry in final states with two same-sign or three leptons and jets using 36 fb\(^{−1}\) of \(\sqrt{s}=13\) TeV \(pp\) collision data with the ATLAS detector JF - Journal of High Energy Physics N2 - A search for strongly produced supersymmetric particles using signatures involving multiple energetic jets and either two isolated same-sign leptons (\(e\) or \(µ\)), or at least three isolated leptons, is presented. The analysis relies on the identification of \(b\)-jets and high missing transverse momentum to achieve good sensitivity. A data sample of proton-proton collisions at \(\sqrt{s} = 13\) TeV recorded with the ATLAS detector at the Large Hadron Collider in 2015 and 2016, corresponding to a total integrated luminosity of 36.1 fb\(^{−1}\), is used for the search. No significant excess over the Standard Model prediction is observed. The results are interpreted in several simplified supersymmetric models featuring \(R\)-parity conservation or \(R\)-parity violation, extending the exclusion limits from previous searches. In models considering gluino pair production, gluino masses are excluded up to 1.87 TeV at 95% confidence level. When bottom squarks are pair-produced and decay to a chargino and a top quark, models with bottom squark masses below 700 GeV and light neutralinos are excluded at 95% confidence level. In addition, model-independent limits are set on a possible contribution of new phenomena to the signal region yields. KW - High energy physics KW - Hadron-Hadron scattering (experiments) KW - Supersymmetry Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-172787 VL - 2017 IS - 09 ER -