TY  - JOUR
A1  - Li, Gang
A1  - Yan, Binghai
A1  - Thomale, Ronny
A1  - Hanke, Werner
T1  - Topological nature and the multiple Dirac cones hidden in Bismuth high-Tc superconductors
JF  - Scientific Reports
N2  - Recent theoretical studies employing density-functional theory have predicted BaBiO\(_{3}\) (when doped with electrons) and YBiO\(_{3}\) to become a topological insulator (TI) with a large topological gap (~0.7 eV). This, together with the natural stability against surface oxidation, makes the Bismuth-Oxide family of special interest for possible applications in quantum information and spintronics. The central question, we study here, is whether the hole-doped Bismuth Oxides, i.e. Ba\(_{1-X}\)K\(_{X}\)BiO\(_{3}\) and BaPb\(_{1-X}\)Bi\(_{X}\)O\(_{3}\), which are "high-Tc" bulk superconducting near 30 K, additionally display in the further vicinity of their Fermi energy E\(_{F}\) a topological gap with a Dirac-type of topological surface state. Our electronic structure calculations predict the K-doped family to emerge as a TI, with a topological gap above E\(_{F}\). Thus, these compounds can become superconductors with hole-doping and potential TIs with additional electron doping. Furthermore, we predict the Bismuth-Oxide family to contain an additional Dirac cone below E\(_{F}\) for further hole doping, which manifests these systems to be candidates for both electron-and hole-doped topological insulators.
KW  - localized wannier functions
KW  - total energy calculations
KW  - phase transitions
KW  - insulator
KW  - BaPb\(_{1-X}\)Bi\(_{X}\)O\(_{3}\)
KW  - temperature
KW  - system
KW  - wave basis set
KW  - initio molecular dynamics
KW  - diffraction
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-148569
VL  - 5
IS  - 10435
ER  - 
TY  - JOUR
A1  - Appel, Mirjam
A1  - Scholz, Claus-Jürgen
A1  - Müller, Tobias
A1  - Dittrich, Marcus
A1  - König, Christian
A1  - Bockstaller, Marie
A1  - Oguz, Tuba
A1  - Khalili, Afshin
A1  - Antwi-Adjei, Emmanuel
A1  - Schauer, Tamas
A1  - Margulies, Carla
A1  - Tanimoto, Hiromu
A1  - Yarali, Ayse
T1  - Genome-Wide Association Analyses Point to Candidate Genes for Electric Shock Avoidance in Drosophila melanogaster
JF  - PLoS ONE
N2  - Electric shock is a common stimulus for nociception-research and the most widely used reinforcement in aversive associative learning experiments. Yet, nothing is known about the mechanisms it recruits at the periphery. To help fill this gap, we undertook a genome-wide association analysis using 38 inbred Drosophila melanogaster strains, which avoided shock to varying extents. We identified 514 genes whose expression levels and/or sequences covaried with shock avoidance scores. We independently scrutinized 14 of these genes using mutants, validating the effect of 7 of them on shock avoidance. This emphasizes the value of our candidate gene list as a guide for follow-up research. In addition, by integrating our association results with external protein-protein interaction data we obtained a shock avoidance- associated network of 38 genes. Both this network and the original candidate list contained a substantial number of genes that affect mechanosensory bristles, which are hairlike organs distributed across the fly's body. These results may point to a potential role for mechanosensory bristles in shock sensation. Thus, we not only provide a first list of candidate genes for shock avoidance, but also point to an interesting new hypothesis on nociceptive mechanisms.
KW  - functional analysis
KW  - disruption project
KW  - natural variation
KW  - complex traits
KW  - networks
KW  - behavior
KW  - flies
KW  - temperature
KW  - genetics
KW  - painful
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-152006
VL  - 10
IS  - 5
ER  -