TY  - JOUR
A1  - Nass, Maximilian
A1  - Weissbrich, Benedikt
A1  - Huber, Moritz
A1  - Schneider, Elisabeth Marion
A1  - Weiss, Manfred
T1  - BK viremia in critically ill surgical patients with hemorrhagic or septic shock
JF  - BMC Research Notes
N2  - Background
Infections with polyomavirus BK virus (BKV) are a common cause of renal dysfunction after renal transplantation and may also be harmful in surgical patients with shock. The aim of the present study was to determine the frequency of BKV viremia in critically ill surgical patients with septic or hemorrhagic shock, and, if viremia is detectable, whether viremia may be associated with renal dysfunction.
Findings
A total of 125 plasma samples from 44 critically ill surgical patients with septic or hemorrhagic shock were tested by real-time polymerase chain reaction (PCR) for BKV DNA during their stay on the intensive care unit (ICU). BKV viremia occurred in four patients, i.e. in three of the septic and in one of the hemorrhagic shock group. There was no association between viremia and renal dysfunction. All positive samples contained a low viral load (< 500 copies/ml).
Conclusions
Since BK viremia was rarely found and with low viral load only in critically ill surgical patients with shock, it is very unlikely that BK viremia results in BK nephropathy later on.
KW  - acute kidney injury
KW  - BK virus
KW  - polyomavirus
KW  - critically ill
KW  - sepsis
KW  - shock
Y1  - 2012
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-124136
VL  - 5
IS  - 100
ER  -