TY  - JOUR
A1  - Yurdadogan, Tino
A1  - Malsch, Carolin
A1  - Kotseva, Kornelia
A1  - Wood, David
A1  - Leyh, Rainer
A1  - Ertl, Georg
A1  - Karmann, Wolfgang
A1  - Müller-Scholden, Lara
A1  - Morbach, Caroline
A1  - Breuning, Margret
A1  - Wagner, Martin
A1  - Gelbrich, Götz
A1  - Bots, Michiel L.
A1  - Heuschmann, Peter U.
A1  - Störk, Stefan
T1  - Functional versus morphological assessment of vascular age in patients with coronary heart disease
JF  - Scientific Reports
N2  - Communicating cardiovascular risk based on individual vascular age (VA) is a well acknowledged concept in patient education and disease prevention. VA may be derived functionally, e.g. by measurement of pulse wave velocity (PWV), or morphologically, e.g. by assessment of carotid intima-media thickness (cIMT). The purpose of this study was to investigate whether both approaches produce similar results. Within the context of the German subset of the EUROASPIRE IV survey, 501 patients with coronary heart disease underwent (a) oscillometric PWV measurement at the aortic, carotid-femoral and brachial-ankle site (PWVao, PWVcf, PWVba) and derivation of the aortic augmentation index (AIao); (b) bilateral cIMT assessment by high-resolution ultrasound at three sites (common, bulb, internal). Respective VA was calculated using published equations. According to VA derived from PWV, most patients exhibited values below chronological age indicating a counterintuitive healthier-than-anticipated vascular status: for VA(PWVao) in 68% of patients; for VA\(_{AIao}\) in 52% of patients. By contrast, VA derived from cIMT delivered opposite results: e.g. according to VA\(_{total-cIMT}\) accelerated vascular aging in 75% of patients. To strengthen the concept of VA, further efforts are needed to better standardise the current approaches to estimate VA and, thereby, to improve comparability and clinical utility.
KW  - arterial stiffening
KW  - atherosclerosis
KW  - calcification
KW  - carotid artery disease
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-265810
VL  - 11
IS  - 1
ER  - 
TY  - JOUR
A1  - Kotseva, Kornelia
A1  - De Backer, Guy
A1  - De Bacquer, Dirk
A1  - Rydén, Lars
A1  - Hoes, Arno
A1  - Grobbee, Diederick
A1  - Maggioni, Aldo
A1  - Marques-Vidal, Pedro
A1  - Jennings, Catriona
A1  - Abreu, Ana
A1  - Aguiar, Carlos
A1  - Badariene, Jolita
A1  - Bruthans, Jan
A1  - Castro Conde, Almudena
A1  - Cifkova, Renata
A1  - Crowley, Jim
A1  - Davletov, Kairat
A1  - Deckers, Jaap
A1  - De Smedt, Delphine
A1  - De Sutter, Johan
A1  - Dilic, Mirza
A1  - Dolzhenko, Marina
A1  - Dzerve, Vilnis
A1  - Erglis, Andrejs
A1  - Fras, Zlatko
A1  - Gaita, Dan
A1  - Gotcheva, Nina
A1  - Heuschmann, Peter
A1  - Hasan-Ali, Hosam
A1  - Jankowski, Piotr
A1  - Lalic, Nebojsa
A1  - Lehto, Seppo
A1  - Lovic, Dragan
A1  - Mancas, Silvia
A1  - Mellbin, Linda
A1  - Milicic, Davor
A1  - Mirrakhimov, Erkin
A1  - Oganov, Rafael
A1  - Pogosova, Nana
A1  - Reiner, Zeljko
A1  - Stöerk, Stefan
A1  - Tokgözoğlu, Lâle
A1  - Tsioufis, Costas
A1  - Vulic, Dusko
A1  - Wood, David
T1  - Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry
JF  - European Journal of Preventive Cardiology
N2  - Aims
The aim of this study was to determine whether the Joint European Societies guidelines on secondary cardiovascular prevention are followed in everyday practice.
	
Design
A cross-sectional ESC-EORP survey (EUROASPIRE V) at 131 centres in 81 regions in 27 countries.
	
Methods
Patients (<80 years old) with verified coronary artery events or interventions were interviewed and examined ≥6 months later.
	
Results
A total of 8261 patients (females 26%) were interviewed. Nineteen per cent smoked and 55% of them were persistent smokers, 38% were obese (body mass index ≥30 kg/m2), 59% were centrally obese (waist circumference: men ≥102 cm; women ≥88 cm) while 66% were physically active <30 min 5 times/week. Forty-two per cent had a blood pressure ≥140/90 mmHg (≥140/85 if diabetic), 71% had low-density lipoprotein cholesterol ≥1.8 mmol/L (≥70 mg/dL) and 29% reported having diabetes. Cardioprotective medication was: anti-platelets 93%, beta-blockers 81%, angiotensin-converting enzyme inhibitors/angiotensin receptor blockers 75% and statins 80%.
	
Conclusion
A large majority of coronary patients have unhealthy lifestyles in terms of smoking, diet and sedentary behaviour, which adversely impacts major cardiovascular risk factors. A majority did not achieve their blood pressure, low-density lipoprotein cholesterol and glucose targets. Cardiovascular prevention requires modern preventive cardiology programmes delivered by interdisciplinary teams of healthcare professionals addressing all aspects of lifestyle and risk factor management, in order to reduce the risk of recurrent cardiovascular events.
KW  - EUROASPIRE
KW  - lifestyle
KW  - cardiovascular risk factors
KW  - secondary prevention
KW  - guidelines
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-205526
SN  - 2047-4873
SN  - 2047-4881
N1  - This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
VL  - 26
IS  - 8
ER  -