TY  - JOUR
A1  - Jakobson, Liina
A1  - Vaahtera, Lauri
A1  - Tõldsepp, Kadri
A1  - Nuhkat, Maris
A1  - Wang, Cun
A1  - Wang, Yuh-Shuh
A1  - Hõrak, Hanna
A1  - Valk, Ervin
A1  - Pechter, Priit
A1  - Sindarovska, Yana
A1  - Tang, Jing
A1  - Xiao, Chuanlei
A1  - Xu, Yang
A1  - Talas, Ulvi Gerst
A1  - García-Sosa, Alfonso T.
A1  - Kangasjärvi, Saijaliisa
A1  - Maran, Uko
A1  - Remm, Maido
A1  - Roelfsema, M. Rob G.
A1  - Hu, Honghong
A1  - Kangasjärvi, Jaakko
A1  - Loog, Mart
A1  - Schroeder, Julian I.
A1  - Kollist, Hannes
A1  - Brosché, Mikael
T1  - Natural Variation in Arabidopsis Cvi-0 Accession Reveals an Important Role of MPK12 in Guard Cell CO\(_{2}\) Signaling
JF  - PLoS Biology
N2  - Plant gas exchange is regulated by guard cells that form stomatal pores. Stomatal adjustments are crucial for plant survival; they regulate uptake of CO\(_{2}\) for photosynthesis, loss of water, and entrance of air pollutants such as ozone. We mapped ozone hypersensitivity, more open stomata, and stomatal CO\(_{2}\)-insensitivity phenotypes of the Arabidopsis thaliana accession Cvi-0 to a single amino acid substitution in MITOGEN-ACTIVATED PROTEIN (MAP) KINASE 12 (MPK12). In parallel, we showed that stomatal CO\(_{2}\)-insensitivity phenotypes of a mutant cis (CO\(_{2}\)-insensitive) were caused by a deletion of MPK12. Lack of MPK12 impaired bicarbonate-induced activation of S-type anion channels. We demonstrated that MPK12 interacted with the protein kinase HIGH LEAF TEMPERATURE 1 (HT1)—a central node in guard cell CO\(_{2}\) signaling—and that MPK12 functions as an inhibitor of HT1. These data provide a new function for plant MPKs as protein kinase inhibitors and suggest a mechanism through which guard cell CO\(_{2}\) signaling controls plant water management.
KW  - MPK12
KW  - CO\(_{2}\) signaling
KW  - Arabidopsis thaliana
KW  - Cvi-0
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-166657
VL  - 14
IS  - 12
ER  -