TY  - JOUR
A1  - Bauer, Hannah
A1  - Concha Mendoza, Gustavo Andrés
A1  - Kreienbrock, Lothar
A1  - Hartmann, Maria
A1  - Frickmann, Hagen
A1  - Kann, Simone
T1  - Prevalence of common diseases in Indigenous people in Colombia
JF  - Tropical Medicine and Infectious Disease
N2  - The Indigenous tribe called the Wiwa lives retracted in the Sierra Nevada de Santa Marta, Colombia. Little is known about their health status and whether the health care system in place covers their needs. In 2017 and 2018, a permanent physician was in charge for the Wiwa. Diseases and complaints were registered, ranked, and classified with the ICD-10 coding. Datasets from the Indigenous health care provider Dusakawi, collected from local health points and health brigades travelling sporadically into the fields for short visits, were compared. Furthermore, a list of provided medication was evaluated regarding the recorded needs. The most common complaints found were respiratory, infectious and parasitic, and digestive diseases. The top ten diagnoses collected in the health points and in the health brigade datasets were similar, although with a different ranking. The available medication showed a basic coverage only, with a critical lack of treatment for many severe, chronic, and life-threatening diseases. Most of the detected diseases in the Indigenous population are avoidable by an improvement in health care access, an expansion of the provided medication, and an increase in knowledge, hygiene, and life standards.
KW  - Chagas disease
KW  - indigenous
KW  - public health
KW  - Colombia
KW  - Sierra Nevada
KW  - neglected groups
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-278953
SN  - 2414-6366
VL  - 7
IS  - 6
ER  - 
TY  - JOUR
A1  - Kann, Simone
A1  - Blessmann, Joerg
A1  - Winkelmann, Yvonne
A1  - Hansen, Jessica
A1  - Maya Amaya, Leonardo J.
A1  - Rivera Salcedo, Gadith E.
A1  - Halas, Hussein El
A1  - Schmidt‐Chanasit, Jonas
A1  - Keoviengkhone, Latdamone
A1  - Sopraseuth, Vatsana
A1  - Deschermeier, Christina
A1  - Mika, Angela
T1  - Dengue virus detection in Lao PDR and Colombia: Comparative evaluation of PCR tests
JF  - Tropical Medicine & International Health
N2  - Objectives
Dengue virus (DENV) detection by polymerase chain reaction (PCR) facilitates diagnosis of dengue fever, which is the most frequent arboviral disease globally. Two studies were performed in countries with high dengue incidence, to assess the diagnostic performance of different PCR techniques.
Methods/Results
Two hundred and seventy‐nine acute phase blood samples from febrile patients were analyzed for DENV by the RealStar Dengue RT‐PCR kit (Altona Diagnostics) as gold standard in comparison with the Tropical Fever Core multiplex PCR (Fast Track Diagnostics). In total, 102 samples collected in Savannakhet Province (Lao PDR, Southeast Asia) in 2013 and 35 samples from Valledupar (Colombia, South America) tested positive for DENV by RealStar RT‐PCR. In comparison, the Tropical Fever Core multiplex PCR detected 65.0% (65/102) and 68.6% (24/35) of these samples as positive for DENV in Savannakhet and Valledupar, respectively. Diagnostic sensitivity of the multiplex PCR strongly correlated with viral load. A subset of DENV PCR‐confirmed samples was additionally tested by BNITM in house Dengue Type RT‐PCR in comparison with two commercial test kits (RealStar Dengue Type RT‐PCR [Altona Diagnostics], Dengue differentiation PCR [Fast Track Diagnostics]). The leading dengue serotype in Savannakhet was DENV‐3 (58% [29/50]), while DENV‐1 (53.8% [14/26]) was the predominant serotype found in samples collected in Valledupar by BNITM‐type PCR. However, three DENV serotypes were circulating in Valledupar and in Savannakhet. In 2015, additional studies found predominantly DENV‐4 (71% [12/17]) in Savannakhet.
Conclusions
Both studies emphasized that routine diagnostics in both regions will benefit from an expanded use of highly sensitive pan‐dengue PCRs.
KW  - Colombia
KW  - dengue infections
KW  - dengue serotypes
KW  - Lao PDR
KW  - PCR diagnostics
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-262703
VL  - 26
IS  - 10
SP  - 1296
EP  - 1302
ER  -