TY - RPRT ED - Nieswandt, Bernhard T1 - Platelets – Molecular, cellular and systemic functions in health and disease T1 - Thrombozyten – molekulare, zelluläre und systemische Funktionen unter physiologischen und pathologischen Bedingungen (SFB/TR240 - Abschlussbericht BT - Final Report (2018/2 - 2023/1) N2 - Besides their central role in haemostasis and thrombosis, platelets are increasingly recognised as versatile effector cells in inflammation, the innate and adaptive immune response, extracellular matrix reorganisation and fibrosis, maintenance of barrier and organ integrity, and host response to pathogens. These platelet functions, referred to as thrombo-inflammation and immunothrombosis, have gained major attention in the COVID-19 pandemic, where patients develop an inflammatory disease state with severe and life-threatening thromboembolic complications. In the CRC/TR 240, a highly interdisciplinary team of basic, translational and clinical scientists explored these emerging roles of platelets with the aim to develop novel treatment concepts for cardiovascular disorders and beyond. We have i) unravelled mechanisms leading to life-threatening thromboembolic complica-tions following vaccination against SARS-CoV-2 with adenoviral vector-based vaccines, ii) identified unrecognised functions of platelet receptors and their regulation, offering new potential targets for pharmacological intervention and iii) developed new methodology to study the biology of megakar-yocytes (MKs), the precursor cells of platelets in the bone marrow, which lay the foundation for the modulation of platelet biogenesis and function. The projects of the CRC/TR 240 built on the unique expertise of our research network and focussed on the following complementary fields: (A) Cell bi-ology of megakaryocytes and platelets and (B) Platelets as regulators and effectors in disease. To achieve this aim, we followed a comprehensive approach starting out from in vitro systems and animal models to clinical research with large prospective patient cohorts and data-/biobanking. Despite the comparably short funding period the CRC/TR 240 discovered basic new mechanisms of platelet biogenesis, signal transduction and effector function and identified potential MK/platelet-specific molecular targets for diagnosis and therapy of thrombotic, haemorrhagic and thrombo-inflammatory disease states. N2 - Thrombozyten sind von zentraler Bedeutung für die Hämostase, aber auch bei der Entstehung akuter thrombotischer Erkrankungen wie Herzinfarkt oder Schlaganfall. Darüber hinaus sind Thrombozyten aber auch vielseitige Effektorzellen von Entzündungsprozessen, der angeborenen Immunität, bei zellulären Abwehrmechanismen sowie bei der Aufrechterhaltung der Gefäß- und Organintegrität. Diese neuen, als Thrombo-Inflammation und Immunothrombose bezeichneten Funktionen haben im Rahmen der COVID-19 Pandemie große Aufmerksamkeit erlangt, da betroffene Patienten systemische Entzündungszustände in Verbindung mit thromboembolischen Komplikationen aufweisen, die oft auch tödlich verlaufen. Im SFB/TR 240 arbeitete ein interdisziplinäres Team von grundlagenorientierten, translationalen und klinischen Wissenschaftlern zusammen an der Erforschung dieser neuartigen Thrombozytenfunktionen mit dem Ziel, neue verbesserte Therapiemöglichkeiten für kardiovaskuläre, aber auch andere Erkrankungen zu entwickeln. Während der Förderphase haben wir i) die Mechanismen aufgeklärt, die in seltenen Fällen nach Impfung mit Adenovirus-basierten Vakzinen gegen Sars-CoV-2 zu lebensbedrohlichen thromboembolischen Komplikationen führten, ii) neue Funktionen und Regulationsmechanismen thrombozytärer Rezeptoren identifiziert, die Grundlage zur therapeutischen Intervention sein könnten und iii) neue Technologien entwickelt, die vertiefte Studien zur Biologie der Megakaryozyten, den Vorläuferzellen der Thrombozyten im Knochenmark, ermöglichen und den Weg zu einer gezielten Beeinflussung der Thrombozytenbiogenese und –funktion ebnen könnten. Die Projekte des TR 240 konzentrierten sich auf die folgenden komplementären Forschungsgebiete: (A) Zellbiologie der Megakaryozyten und Thrombozyten mit dem Ziel eines verbesserten Verständnisses der grundlegenden Funktionen beider Zelltypen und (B) Thrombozyten als Modulatoren und Effektoren bei Erkrankungen. Um dieses Ziel zu erreichen, wurde ein sehr umfassender Ansatz verfolgt, der sich von in vitro Systemen über Tiermodelle bis hin zur klinischen Forschung mit Biobanken und großen, prospektiven Patientenkohorten erstreckte. Der SFB/TR 240 konnte in der vergleichsweisen kurzen Zeit seiner Förderung grundlegend neue Erkenntnisse zu den Mechanismen der Thrombozytenbiogenese, Thrombozyten-Signaltransduktion und -Effektorfunktionen erarbeiten und neue MK/Thrombozyten-spezifische Angriffspunkte für Diag-nose und Therapie thrombotischer, hämorrhagischer und thrombo-inflammatorischer Erkrankungen identifizieren. KW - Thrombozyt KW - platelets KW - thrombo-inflammation KW - haemostasis KW - stroke KW - megakaryocytes KW - Sonderforschungsbereich Transregio 240 KW - Bericht KW - Collaborative Research Center KW - Experimental Biomedicine Y1 - 2024 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-359636 ER - TY - RPRT A1 - Nord, Ilona A1 - Petzke, Judith T1 - Religious Education in the digital change. Concepts and reflections from a German context N2 - The article presents results from the project Religious Education Laboratory digital (RELab digital): At a time when exclusive access to religion in the classroom seems less and less plausible, the concept of digital religion education we propose leads back to the existential needs for religion. It can refer to the thematic fields of digital religions, which in turn are not new for religious education, but remix its traditions and themes in the mirror of transforming communication cultures: authority, community, truth, communication, autonomy, religion, identity, and ritual. Chapter 1 contains a description of the project structure. Chapter 2 is dedicated to the pedagogical challenge of teaching Religious Education (RE) in the digital change. Chapter 3 reflects from a pedagogical standpoint on empirical findings of the project, which were developed in the context of classroom observations and interviews. Chapter 4 focuses on topics related to the profession of teachers: What self-concepts are pursued by teachers of Religious Education and/or can be reconstructed through the way they act in the classroom? How can the often critical perceptions of teachers who use digital media in religious education be put to good use in the future? The conclusion bundles the most important insights and highlights examples of further research. KW - Digitalisierung KW - Lehrerbildung KW - Mediendidaktik KW - Religionsunterricht KW - Religiöse Bildung KW - Digital Religions KW - Digital Religions Education KW - digital change KW - media literacy KW - Religious Education Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-328582 N1 - German version available at https://doi.org/10.25972/OPUS-31978. Revised version of https://doi.org/10.25972/OPUS-32280 ET - revised version ER - TY - RPRT A1 - Bösch, Carolin A1 - Stieler, Malena A1 - Lydon, Salomon A1 - Hesse, Martin A1 - Ali, Hassan A1 - Finzel, Matthias A1 - Faraz Ali, Syed A1 - Salian, Yash A1 - Alnoor, Hiba A1 - John, Jeena A1 - Lakkad, Harsh A1 - Bhosale, Devraj A1 - Jafarian, Timon A1 - Parvathi, Uma A1 - Ezzatpoor, Narges A1 - Datar, Tanuja T1 - Venus Research Station N2 - Because of the extreme conditions in the atmosphere, Venus has been less explored than for example Mars. Only a few probes have been able to survive on the surface for very short periods in the past and have sent data. The atmosphere is also far from being fully explored. It could even be that building blocks of life can be found in more moderate layers of the planet’s atmosphere. It can therefore be assumed that the planet Venus will increasingly become a focus of exploration. One way to collect significantly more data in situ is to build and operate an atmospheric research station over an extended period of time. This could carry out measurements at different positions and at different times and thus significantly expand our knowledge of the planet. In this work, the design of a Venus Research Station floating within the Venusian atmosphere is presented, which is complemented by the design of deployable atmospheric Scouts. The design of these components is done on a conceptual basis. T3 - Raumfahrttechnik und Extraterrestrik - 4 KW - Venus KW - Research Station Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-328695 SN - 2747-9374 ER - TY - RPRT A1 - Bofinger, Peter A1 - Geißendörfer, Lisa A1 - Haas, Thomas A1 - Mayer, Fabian T1 - Credit as an Instrument for Growth: A Monetary Explanation of the Chinese Growth Story N2 - This study describes the Chinese growth model over the past 40 years. We show that China's growth model, with its dominant role of the banking system and "the banker", is a perfect illustration of the necessity and power of Schumpeter's "monetary analysis". This approach has allowed us to elaborate theoretically and empirically the uniqueness of the Chinese model. In our empirical analysis, we use a new dataset of Chinese provincial data to analyze the impact of the financial system, especially banks, on Chinese economic development. We also empirically assess the role of the financial system in Chinese industrial policy and provide case studies of the effects of industrial policy in specific sectors. Finally, we also discuss macroeconomic dimensions of the Chinese growth process and lessons that can be drawn from the Chinese experience for other countries. T3 - Würzburg Economic Papers (W. E. P.) - 107 KW - Industriepolitik KW - Bank-led Growth KW - China KW - Wirtschaftswachstum KW - Wirtschaftsentwicklung KW - Industrial Policy KW - China KW - Strategic Emerging Industries KW - Finance-growth nexus KW - Finance KW - Economic growth KW - Economic development KW - Bank credit Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-328804 ER - TY - RPRT A1 - Nord, Ilona A1 - Petzke, Judith T1 - Religious Education in the digital change. Concepts and reflections from a German context N2 - The article presents results from the project Religious Education Laboratory digital (RELab digital): At a time when exclusive access to religion in the classroom seems less and less plausible, the concept of digital religion education we propose leads back to the existential needs for religion. It can refer to the thematic fields of digital religions, which in turn are not new for religious education, but remix its traditions and themes in the mirror of transforming communication cultures: authority, community, truth, communication, autonomy, religion, identity, and ritual. Chapter 1 contains a description of the project structure. Chapter 2 is dedicated to the pedagogical challenge of teaching Religious Education (RE) in the digital change. Chapter 3 reflects from a pedagogical standpoint on empirical findings of the project, which were developed in the context of classroom observations and interviews. Chapter 4 focuses on topics related to the profession of teachers: What self-concepts are pursued by teachers of Religious Education and/or can be reconstructed through the way they act in the classroom? How can the often critical perceptions of teachers who use digital media in religious education be put to good use in the future? The conclusion bundles the most important insights and highlights examples of further research. KW - Digitalisierung KW - Lehrerbildung KW - Mediendidaktik KW - Religionsunterricht KW - Religiöse Bildung KW - Digital Religions KW - Digital Religions Education KW - digital change KW - media literacy KW - Religious Education Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-322802 N1 - German version available at https://doi.org/10.25972/OPUS-31978. Revised version available at https://doi.org/10.25972/OPUS-32858.“ ER - TY - RPRT A1 - Müller, Jörg A1 - Scherer-Lorenzen, Michael A1 - Ammer, Christian A1 - Eisenhauer, Nico A1 - Seidel, Dominik A1 - Schuldt, Bernhard A1 - Biedermann, Peter A1 - Schmitt, Thomas A1 - Künzer, Claudia A1 - Wegmann, Martin A1 - Cesarz, Simone A1 - Peters, Marcell A1 - Feldhaar, Heike A1 - Steffan-Dewenter, Ingolf A1 - Claßen, Alice A1 - Bässler, Claus A1 - von Oheimb, Goddert A1 - Fichtner, Andreas A1 - Thorn, Simon A1 - Weisser, Wolfgang T1 - BETA-FOR: Erhöhung der strukturellen Diversität zwischen Waldbeständen zur Erhöhung der Multidiversität und Multifunktionalität in Produktionswäldern. Antragstext für die DFG Forschungsgruppe FOR 5375 T1 - BETA-FOR: Enhancing the structural diversity between patches for improving multidiversity and multifunctionality in production forests. Proposal for DFG Research Unit FOR 5375 BT - β\(_4\) : Proposal for the 1st phase (2022-2026) of the DFG Research Unit FOR 5375/1 (DFG Forschergruppe FOR 5375/1 – BETA-FOR), Fabrikschleichach, October 2021 N2 - Der in jüngster Zeit beobachtete kontinuierliche Verlust der β-Diversität in Ökosystemen deutet auf homogene Gemeinschaften auf Landschaftsebene hin, was hauptsächlich auf die steigende Landnutzungsintensität zurückgeführt wird. Biologische Vielfalt ist mit zahlreichen Funktionen und der Stabilität von Ökosystemen verknüpft. Es ist daher zu erwarten, dass eine abnehmende β-Diversität auch die Multifunktionalität verringert. Wir kombinieren hier Fachwissen aus der Forstwissenschaft, der Ökologie, der Fernerkundung, der chemischen Ökologie und der Statistik in einem gemeinschaftlichen und experimentellen β-Diversitätsdesign, um einerseits die Auswirkungen der Homogenisierung zu bewerten und andererseits Konzepte zu entwickeln, um negative Auswirkungen durch Homogenisierung in Wäldern rückgängig zu machen. Konkret werden wir uns mit der Frage beschäftigen, ob die Verbesserung der strukturellen β-Komplexität (ESBC) in Wäldern durch Waldbau oder natürliche Störungen die Biodiversität und Multifunktionalität in ehemals homogenen Produktionswäldern erhöhen kann. Unser Ansatz wird mögliche Mechanismen hinter den beobachteten Homogenisierungs-Diversitäts-Beziehungen identifizieren und zeigen, wie sich diese auf die Multifunktionalität auswirken. An elf Standorten in ganz Deutschland haben wir dazu zwei Waldbestände als zwei kleine "Waldlandschaften" ausgewählt. In einem dieser beiden Bestände haben wir ESBC (Enhancement of Structural Beta Complexity)-Behandlungen durchgeführt. Im zweiten, dem Kontrollbestand, werden wir die gleich Anzahl 50x50m Parzellen ohne ESBC einrichten. Auf allen Parzellen werden wir 18 taxonomische Artengruppen aller trophischer Ebenen und 21 Ökosystemfunktionen, einschließlich der wichtigsten Funktionen in Wäldern der gemäßigten Zonen, messen. Der statistische Rahmen wird eine umfassende Analyse der Biodiversität ermöglichen, indem verschiedenen Aspekte (taxonomische, funktionelle und phylogenetische Vielfalt) auf verschiedenen Skalenebenen (α-, β-, γ-Diversität) quantifiziert werden. Um die Gesamtdiversität zu kombinieren, werden wir das Konzept der Multidiversität auf die 18 Taxa anwenden. Wir werden neue Ansätze zur Quantifizierung und Aufteilung der Multifunktionalität auf α- und β-Skalen verwenden und entwickeln. Durch die experimentelle Beschreibung des Zusammenhangs zwischen β-Diversität und Multifunktionalität in einer Reallandschaft wird unsere Forschung einen neuen Weg einschlagen. Darüber hinaus werden wir dazu beitragen, verbesserte Leitlinien für waldbauliche Konzepte und für das Management natürlicher Störungen zu entwickeln, um Homogenisierungseffekte der Vergangenheit umzukehren. N2 - The recently observed consistent loss of β-diversity across ecosystems indicates increasingly homogeneous communities in patches of landscapes, mainly caused by increasing land-use intensity. Biodiversity is related to numerous ecosystem functions and stability. Therefore, decreasing β-diversity is also expected to reduce multifunctionality. To assess the impact of homogenization and to develop guidelines to reverse its potentially negative effects, we combine expertise from forest science, ecology, remote sensing, chemical ecology and statistics in a collaborative and experimental β-diversity approach. Specifically, we will address the question whether the Enhancement of Structural Beta Complexity (ESBC) in forests by silviculture or natural disturbances will increase biodiversity and multifunctionality in formerly homogeneously structured production forests. Our approach will identify potential mechanisms behind observed homogenization-diversity-relationships and show how these translate into effects on multifunctionality. At eleven forest sites throughout Germany, we selected two districts as two types of small ‘forest landscapes’. In one of these two districts, we established ESBC treatments (nine differently treated 50x50 m patches with a focus on canopy cover and deadwood features). In the second, the control district, we will establish nine patches without ESBC. By a comprehensive sampling, we will monitor 18 taxonomic groups and measure 21 ecosystem functions, including key functions in temperate forests, on all patches. The statistical framework will allow a comprehensive biodiversity assessment by quantifying the different aspects of multitrophic biodiversity (taxonomical, functional and phylogenetic diversity) on different levels of biodiversity (α-, β-, γ-diversity). To combine overall diversity, we will apply the concept of multidiversity across the 18 taxa. We will use and develop new approaches for quantification and partitioning of multifunctionality at α- and β- scales. Overall, our study will herald a new research avenue, namely by experimentally describing the link between β-diversity and multifunctionality. Furthermore, we will help to develop guidelines for improved silvicultural concepts and concepts for management of natural disturbances in temperate forests reversing past homogenization effects. KW - Waldökosystem KW - Biodiversität KW - BETA-Multifunktionalität KW - beta-multifunctionality KW - BETA-Diversität KW - beta diversity KW - Forschungsstation Fabrikschleichach Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-290849 ER - TY - RPRT A1 - Groß, Lennart T1 - Advices derived from troubleshooting a sensor-based adaptive optics direct stochastic optical reconstruction microscope T1 - Hinweise aus der Fehleranalyse eines Mikroskops mit direkter stochastischer optischer Rekonstruktion und sensorgestützter adaptiver Optik N2 - One rarely finds practical guidelines for the implementation of complex optical setups. Here, we aim to provide technical details on the decision making of building and revising a custom sensor-based adaptive optics (AO) direct stochastic optical reconstruction microscope (dSTORM) to provide practical assistance in setting up or troubleshooting similar devices. The foundation of this report is an instrument constructed as part of a master's thesis in 2021, which was built for deep tissue imaging. The setup is presented in the following way: (1) An optical and mechanical overview of the system at the beginning of this internship is given. (2) The optical components are described in detail in the order at which the light passes through, highlighting their working principle and implementation in the system. The optical component include (2A) a focus on even sample illumination, (2B) restoring telecentricity when working with commercial microscope bodies, (2C) the AO elements, namely the deformable mirror (DM) and the wavefront sensor, and their integration, and (2D) the separation of wavefront and image capture using fluorescent beads and a dichroic mirror. After addressing the limitations of the existing setup, modification options are derived. The modifications include the implementation of adjustment only light paths to improve system stability and revise the degrees of freedom of the components and changes in lens choices to meet the specifications of the AO components. Last, the capabilities of the modified setup are presented and discussed: (1) First, we enable epifluorescence imaging of bead samples through 180 µm unstained murine hippocampal tissue with wavefront error correction of ~ 90 %. Point spread function, wavefront shape and Zernike decomposition of bead samples are presented. (2) Second, we move from epifluorescent to dSTORM imaging of tubulin stained primary mouse hippocampal cells, which are imaged through up to 180 µm of unstained murine hippocampal tissue. We show that full width at half maximum (FWHM) of prominent features can be reduced in size by nearly a magnitude from uncorrected epiflourescence images to dSTORM images corrected by the adaptive optics. We present dSTORM localization count and FWHM of prominent features as as a function of imaging depth. N2 - Praktische Leitlinien für die Implementierung komplexer optischer Systeme sind selten zu finden. Hier wollen wir technische Details zur Entscheidungsfindung beim Bau und der Überarbeitung eines maßgefertigten Mikroskops mit sensorgestützter adaptiver Optik (AO) und direkter stochastischer optischer Rekonstruktion (dSTORM) bereitstellen, um praktische Hilfestellung bei der Einrichtung oder Fehlerbehebung ähnlicher Geräte zu geben. Grundlage dieses Berichts ist ein Instrument, das im Rahmen einer Masterarbeit im Jahr 2021 für die Abbildung von tiefem Gewebe gebaut wurde. Der Aufbau wird wie folgt dargestellt: (1) Es wird ein optischer und mechanischer Überblick über das System zu Beginn dieses Praktikums gegeben. (2) Die optischen Komponenten werden in der Reihenfolge, in der das Licht sie durchläuft, detailliert beschrieben und ihre Funktionsweise und Umsetzung im System hervorgehoben. Zu den optischen Komponenten gehören (2A) ein Fokus auf gleichmäßige Probenausleuchtung, (2B) die Wiederherstellung der Telezentrizität bei der Arbeit mit handelsüblichen Mikroskopkörpern, (2C) die AO-Elemente, nämlich der deformierbare Spiegel (DM) und der Wellenfrontsensor, und deren Integration, sowie (2D) die Trennung von Wellenfront- und Bilderfassung mittels fluoreszierender Beads und einem dichroitischen Spiegel. Nachdem die Einschränkungen des bestehenden Aufbaus angesprochen wurden, werden Modifikationsmöglichkeiten abgeleitet. Die Modifikationen umfassen die Implementierung von Justage-Lichtpfaden, um die Systemstabilität zu verbessern und die Freiheitsgrade der Komponenten zu überarbeiten, sowie Änderungen bei der Auswahl der Linsen, um die Spezifikationen der AO-Komponenten zu erfüllen. Abschließend werden die Ergebnisse des modifizierten Aufbaus vorgestellt und diskutiert: (1) Zunächst ermöglichen wir die Epifluoreszenz-Abbildung von Bead-Proben durch 180 µm ungefärbtes Hippocampus-Gewebe der Maus mit einer Wellenfront-Fehlerkorrektur von ~ 90 %. Es werden Punktspreizungsfunktion, Wellenfrontform und Zernike-Zerlegung von Bead-Proben vorgestellt. (2) Zweitens gehen wir von der Epifluoreszenz zur dSTORM-Bildgebung von Tubulin-gefärbten primären Hippocampuszellen der Maus über, die durch bis zu 180 µm ungefärbtes Hippocampusgewebe der Maus abgebildet werden. Wir zeigen, dass die Halbwertsbreite (Full Width at Half Maximum, FWHM) auffälliger Merkmale von unkorrigierten Epifloureszenz-Bildern zu dSTORM-Bildern, die durch die adaptive Optik korrigiert wurden, um fast eine Größenordnung reduziert werden kann. Wir präsentieren die Anzahl der dSTORM-Lokalisierungen und die FWHM auffälliger Merkmale als Funktion der Abbildungstiefe. KW - Einzelmolekülmikroskopie KW - Adaptive Optik KW - Adaptive Optics KW - Single Molecule Localization Microscopy KW - dSTORM Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-289951 ER - TY - RPRT A1 - Meyer, Constantin A1 - Job, Hubert A1 - Laner, Peter A1 - Omizzolo, Andrea A1 - Kollmann, Nadia A1 - Clare, Jasmin A1 - Vesely, Philipp A1 - Riedler, Walter A1 - Plassmann, Guido A1 - Coronado, Oriana A1 - Praper Gulič, Sergeja A1 - Gulič, Andrej A1 - Koblar, Simon A1 - Teofili, Corrado A1 - Rohringer, Verena A1 - Schoßleitner, Richard A1 - Ainz, Gerhard T1 - OpenSpaceAlps Planning Handbook: Perspectives for consistent safeguarding of open spaces in the Alpine region N2 - In the Alpine region, the continuous consumption of open spaces for settlement areas and technical infrastructure and the associated soil sealing can be observed. This leads primarily to the loss of agricultural land. Depending on the extent of development, there is also increased landscape fragmentation, which is associated with the isolation of natural habitats and the restriction of ecological connectivity, as well as other negative consequences. The OpenSpaceAlps project has addressed this issue and, based on cooperative procedures in several pilot regions, has developed approaches and solution strategies for the sustainable safeguarding of open spaces. This handbook supports the activities and decision-making of various stakeholders, first and foremost planners in public planning authorities. Based on an analysis of the challenges and framework conditions in the Alpine region, the handbook presents and compares central "principles" of open space planning. Furthermore, integrated planning strategies for different spatial categories are discussed. KW - Raumordnung KW - spatial planning KW - Alps KW - OpenSpaceAlps KW - open space KW - transnational cooperation KW - Alpen Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-270401 N1 - German version available at: https://doi.org/10.25972/OPUS-27307. Italian version available at: https://doi.org/10.25972/OPUS-27704. Slovenian version available at: https://doi.org/10.25972/OPUS-28651. N1 - The OpenSpaceAlps project is co-financed by the European Regional Development Fund through the Interreg Alpine Space programme. ER - TY - RPRT A1 - Rossi, Angelo Pio A1 - Maurelli, Francesco A1 - Unnithan, Vikram A1 - Dreger, Hendrik A1 - Mathewos, Kedus A1 - Pradhan, Nayan A1 - Corbeanu, Dan-Andrei A1 - Pozzobon, Riccardo A1 - Massironi, Matteo A1 - Ferrari, Sabrina A1 - Pernechele, Claudia A1 - Paoletti, Lorenzo A1 - Simioni, Emanuele A1 - Maurizio, Pajola A1 - Santagata, Tommaso A1 - Borrmann, Dorit A1 - Nüchter, Andreas A1 - Bredenbeck, Anton A1 - Zevering, Jasper A1 - Arzberger, Fabian A1 - Reyes Mantilla, Camilo Andrés T1 - DAEDALUS - Descent And Exploration in Deep Autonomy of Lava Underground Structures BT - Open Space Innovation Platform (OSIP) Lunar Caves-System Study N2 - The DAEDALUS mission concept aims at exploring and characterising the entrance and initial part of Lunar lava tubes within a compact, tightly integrated spherical robotic device, with a complementary payload set and autonomous capabilities. The mission concept addresses specifically the identification and characterisation of potential resources for future ESA exploration, the local environment of the subsurface and its geologic and compositional structure. A sphere is ideally suited to protect sensors and scientific equipment in rough, uneven environments. It will house laser scanners, cameras and ancillary payloads. The sphere will be lowered into the skylight and will explore the entrance shaft, associated caverns and conduits. Lidar (light detection and ranging) systems produce 3D models with high spatial accuracy independent of lighting conditions and visible features. Hence this will be the primary exploration toolset within the sphere. The additional payload that can be accommodated in the robotic sphere consists of camera systems with panoramic lenses and scanners such as multi-wavelength or single-photon scanners. A moving mass will trigger movements. The tether for lowering the sphere will be used for data communication and powering the equipment during the descending phase. Furthermore, the connector tether-sphere will host a WIFI access point, such that data of the conduit can be transferred to the surface relay station. During the exploration phase, the robot will be disconnected from the cable, and will use wireless communication. Emergency autonomy software will ensure that in case of loss of communication, the robot will continue the nominal mission. T3 - Forschungsberichte in der Robotik = Research Notes in Robotics - 21 KW - Lunar Caves KW - Spherical Robot KW - Lunar Exploration KW - Mapping KW - 3D Laser Scanning KW - Mond KW - Daedalus-Projekt KW - Lava Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-227911 SN - 978-3-945459-33-1 SN - 1868-7466 ER - TY - RPRT A1 - Grigorjew, Alexej A1 - Metzger, Florian A1 - Hoßfeld, Tobias A1 - Specht, Johannes A1 - Götz, Franz-Josef A1 - Schmitt, Jürgen A1 - Chen, Feng T1 - Technical Report on Bridge-Local Guaranteed Latency with Strict Priority Scheduling N2 - Bridge-local latency computation is often regarded with caution, as historic efforts with the Credit-Based Shaper (CBS) showed that CBS requires network wide information for tight bounds. Recently, new shaping mechanisms and timed gates were applied to achieve such guarantees nonetheless, but they require support for these new mechanisms in the forwarding devices. This document presents a per-hop latency bound for individual streams in a class-based network that applies the IEEE 802.1Q strict priority transmission selection algorithm. It is based on self-pacing talkers and uses the accumulated latency fields during the reservation process to provide upper bounds with bridge-local information. The presented delay bound is proven mathematically and then evaluated with respect to its accuracy. It indicates the required information that must be provided for admission control, e.g., implemented by a resource reservation protocol such as IEEE 802.1Qdd. Further, it hints at potential improvements regarding new mechanisms and higher accuracy given more information. KW - Echtzeit KW - Rechnernetz KW - Latenz KW - Ethernet KW - Latency Bound KW - Formal analysis Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-198310 ER -