TY - JOUR A1 - Wilhelm, Gernot T1 - Zur urartäischen Nominalflexion N2 - no Abstract available KW - Urartäisch Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-103511 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Wannagat, U. T1 - Isoelektronische Derivate des Sila-Clofenetamins und des Sila-Mebrophenhydramins T1 - Isoelectronic Derivatives of Sila-Clofenetamine and Sila-Mebrophenhydramine N2 - Isoelectronic derivatives (A and B) and a homolog (C) of the two sila-antihistamines sila-clofenetamine and silamebrophenhydramine were synthesized for the first time by the steps shown in scheme 1. They and their unknown precursors II-IV were characterized by their physical (Table 1) and chemical properties and their structures confinned by lH-NMR and rnass spectroscopy (Tables 2 and 3). The pharrnacological effects of A and B were investigated and compared with those of the corresponding 0-isosteric sila-antihistarnines (Chapter 5). KW - Anorganische Chemie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63574 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Wannagat, U. T1 - Derivate des Sila-Mephenhydramins und Sila-Chlorphenoxamins T1 - Derivatives of Sila-Mephenhydramine and Sila-Ohlorphenoxamine N2 - Derivatives A and B of the two sila-antihistam.ines silamephenhydramine and sila-chlorphenoxamine were synthesized for the first time by the steps shown in scheme 1. They and their precursors III and IV were characterized by their physical (Table 1) and chemical properties and their structures confirmed by NMR and mass spectroscopy (Tables 2 and 3). Their pharmacological effects were investigated and compared with those of the corresponding sila-antihistamines. KW - Anorganische Chemie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63562 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Wannagat, U. T1 - Sila-Analogon des Cicloniumbromids T1 - Sila-Analogue of Ciclonium Bromide N2 - Sila-Analogues B 2 and A 2 of the spasmolytic ciclonium bromide (B 1) respectively the corresponding free base A 1 were synthesized for the first time according to the reaction steps sho·wn in scheme 1, and they and their precursors I and II were characterized by ph;ysical (Table 1} and chemical properties and their structures confirmed by NMR, and mass spectroscopy (Tables 2 and 3}. The pharmacological effects of A 2 and B 2 were investigated and compared with those of the parent carbon compound B 1 (chapter 5). KW - Anorganische Chemie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63556 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Wannagat, U. T1 - Sila-Analoga des Mebrophenhydramins T1 - Sila-Analogues of Mebrophenhydramine N2 - Sila-analogues A 2, B 2 and C 2 of the drug mebrophenhydramine from the class of benzhydryl ethers -were synthesized for the first time by the steps shown in scheme 1, and they and their precurso:rs I-Ill were characterized by their physical (Table 1) and chemical properties, a.nd their structures confirmed by NMR, mass and infrared spectroscopy (Tables 3-5). The histaminolytic and anticholinergic effects of A 2 and C 2 were investigated and compared with some structure-activity relationships of analogue carbon compounds. KW - Anorganische Chemie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63542 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Wannagat, U. T1 - Sila-Analoga des Chlorphenoxamins und des Clofenetamins T1 - Sila-Analogues of Ohlorphenoxamine and Clofenetamine N2 - Sila-ana.logues A 2 and B 2 of two drugs from the benzhydryl ether class, chlorphenoxamine and clofenetamine, were synthesized for the first time by the steps shown in scheme 1. They and their precursors I-VI v;rere characterized by their physical (Table 1) and chemical properties and their structures confirmed by n.m.r., mass and infrared spectroscopy (Tab]es 2-5). Their physiological effects were invest.igated and compared with those of the carbon analogues (Chapter 5). KW - Anorganische Chemie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-63531 ER - TY - JOUR A1 - Christl, Manfred A1 - Freitag, G. T1 - Das Tricyclo[4.1.0.0\(^{2,7}\)]heptenyl-Kation, ein neues Isomer des Tropylium-Ions N2 - No abstract available KW - Organische Chemie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-57985 ER - TY - JOUR A1 - Wilhelm, Gernot T1 - Parrattarna, Sauštatar und die absolute Datierung der Nuzi-Tafeln N2 - No abstract available KW - Archäologie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-51166 ER - TY - JOUR A1 - Bronger, W. A1 - Burschka, Christian T1 - K\(_2\)Ag\(_4\)S\(_3\) und Rb\(_2\)Ag\(_4\)S\(_3\) : Synthese und Struktur T1 - K\(_2\)Ag\(_4\)S\(_3\) and Rb\(_2\)Ag\(_4\)S\(_3\) : Synthesis and Crystal Structure N2 - Durch Umsetzungen von Alkalimetallcarbonaten mit Silber und Schwefel in der Schmelze wurden die ternären Sulfide K2Ag4S3 und Rb2Ag4S3 dargestellt. Röntgenographische Untersuchungen an Einkristallen führten zu einem neuen Schichtenstrukturtyp, in dem röhrenförmige Silber-Schwefel-Anordnungen mit nahezu trigonal planar von Schwefel koordinierten Silberatomen über gemeinsame S-Atome zu Schichten"verknüpft werden, zwischen denen die Alkalimetallatome eingelagert sind. Die monoklinen Elementarzellen enthalten vier Formeleinheiten. Die höchstsymmetrische Raumgruppe ist C2/m. Als Gitterkonstanten ergeben sich: K\(_2\)Ag\(_4\)S\(_3\): a = 17,36(1) A, b = 4,296(2) A, c = 11,603(5) A, B = 108,32(3t; Rb\(_2\)Ag\(_4\)S\(_3\): 80 = 17,88(1) A, b = 4,331(5) A, c = 11,849(5) A, B = 108,58(3)°. N2 - The ternary sulfides K\(_2\)Ag\(_4\)S\(_3\) and Rb\(_2\)Ag\(_4\)S\(_3\) can be synthesized by fusion reactions of alkali carbonates and sulfur with silver. X-ray investigations on single crystals suggest a new layer structure type, with a slightly distorted triangular sulfur coordination around the silver atoms. The sulfur triangles are connected together forming channels which are linked to layers. The alkali metal atoms are intercalated between these layers. The monoclinic unit cells (q. v. Inhaltsübersicht) contain 4 formula units. The space group with the highest possible symmetry is C2/m. KW - Chemie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46569 ER - TY - JOUR A1 - Heller, Dieter A1 - Krüger, Hans-Peter T1 - Analyse dreistufig zu beantwortender Fragebogenitems N2 - In Fragebögen tauchen häufig ternäre Antwortmöglichkeiten auf (z.B. ja - nein - weiß nicht). Für eine Analyse solcher Hems werden Kennwerte vorgeschlagen. Dabei wird ein der Schwierigkeit analoger Popularitätsindex eingeführt, der in p+ den Anteil der Ja-Antworten angibt. Aus p+ und p-, dem Anteil der Nein-Antworten, wird ein Aktualitätsindex definiert, der in den Grenzen zwischen 0 und 1 variiert und die Eliminierung wenig aktueller Fragen gestattet. Zur Bestimmung der Trennschärfe werden Punkt-Vierfelder- oder phi-Koeffizienten angegeben. die aus der Zerlegung des X2 einer 3x2-Tafel in eine 2x2-Tafel und in eine auf die Unbestimmtheitsantwort zurückgehende Restkomponente entstehen. Ebenso werden Koeffizienten für Iteminterkorrelationen aus 3x3-Tafeln und Indizes für die Reliabilität angegeben. N2 - In this paper the question is raised how to proceed in item-analysis if the answers may be given in three ways: "yes", "no" or "don't know". In defining and calculating parameters the following suggestions are made: define the difficulty index of an item as the proportion of the number of "yes" answers p+ within a random sampie of N Ss. Define an index of actuality as a function of p+ p- where p- is the proportion of the number of "no" answers such that min. f(p+p-) = 0 and max. f(p+p-) = 1 and eliminate items having low actuality indices. Define item-discriminating power (item-test correlation) by a point four-fold or phi coefficient determined by partitioning the chi square of a 3x2 contingency table into 2x2 contingency plus a residual due to "don't know" answers. In a similar way define item-intercorrelations on the basis of 3x3 contingency tables and reliability indices. Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41583 ER - TY - JOUR A1 - Krüger, Hans-Peter T1 - Nähe und Distanz in sozialen Beziehungen und ihre quantitative Erfassung N2 - Es wird ein neues soziometrisches Verfahren vorgeschlagen, das in seiner Grundlegung von heute üblichen Wahlverfahren abweicht. Dabei wird versucht, in einem ersten Teil die Gedanken darzustellen, die zur Formulierung der soziometrischen Fragen geführt haben. Im zweiten Teil wird der Gang der Auswertung dargestellt, der ein differenziertes Bild der untersuchten Personen zeichnen soll. Im Teil "Ergebnisse" wird am Beispiel von Extremgruppen gezeigt, was die Methode leisten kann. Schließlich werden noch mögliche Modifikationen des Verfahrens aufgezeigt. Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41446 ER - TY - JOUR A1 - Hommers, Wilfried A1 - Steller, Max A1 - Zienert, Hans Joachim T1 - Psychologische Entlassungsvorbereitung bei jugendlichen Strafgefangenen - Forschungsprogramm eines Vollzugsversuchs N2 - No abstract available KW - Kriminologie / Strafrecht / Zeitschrift / Strafrechtsreform Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-44079 ER - TY - JOUR A1 - Hommers, Wilfried T1 - Zur Frage der Anwendungsbedingungen der Erwartungsmaximierung bei Entscheidungen über Spiele gegen die Natur N2 - Von Aussagen von Vpn ausgehend wird eine Erklärung für die Nichtanwendung der Erwartungsmaximierung in Entscheidungen zwischen Spielen gegen die Natur gegeben, die in einer Untersuchung empirisch bestätigt wurde. Danach hängt die Verwendung der Erwartungsmaximierung von situationalen Bedingungen ab, die den Vpn eine Anwendung des Wahrscheinlichkeitsbegriffs für eine Menge gleichartiger Zufalls experimente nahelegen. Der Befund der Untersuchung kann auch durch die PortfolioTheorie erklärt werden. Zur Beseitigung dieses Dilemmas wird auf die Introspektion zurückgegriffen. N2 - An experimental study of the choice behaviour reported in the present paper, showed that the subjects do not choose the obviously most suitable alternative in a gambling situation. The choice of the obviously most suitable alternative depends upon the application of the cOJ1cept of prob ability by the subjects upon a number of similar chance experiments. Besides, the experimental results reported above, can also be explained 'on the basis of the portfolio theory. This discrepancy can, perhaps be resolved by considering introspection. Resume: L'auteur observe que ses sujets n'appliquent pas, dans des jeux de hasard la strategie qui conduirait a une maximisation des gains. D'apres les explications des sujets, l'application d'une strategie de maximisation dependrait de la situation, a savoir d'une constellation de faits, qui font penser que l'experience obeit aux lois du hasard et se repetera plusieurs fois et de maniere analogue. On pourrait cependant tout aussi bien expliquer les m&mes comportements par la »theorie du portefeuille«. Se fondant sur les explications introspectives de ses sujets, l'auteur donne provisoirement sa preference a la premiere de ces deux explications. KW - Angewandte Psychologie KW - Experimentelle Psychologie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43917 ER - TY - JOUR A1 - Hommers, Wilfried A1 - Steller, Max A1 - Zienert, Hans-Joachim T1 - Möglichkeiten psychologischer Entlassungsvorbereitung bei jugendlichen Strafgefangenen : Forschungsprogramm eines Vollzugsversuchs - Modell-Lernen im Rahmen von Rollen-Trainings N2 - No abstract available KW - Strafvollzug Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43906 ER - TY - JOUR A1 - Hommers, Wilfried T1 - Ein Beitrag über den Einfluß von Durchführungsbedingungen auf das Entscheidungsverhalten von lernbehinderten Sonderschülern N2 - No abstract available KW - Sonderpädagogik Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43810 ER - TY - JOUR A1 - Hommers, Wilfried T1 - Zur Validität der Portfolio-Theorie im Entscheidungsverhalten von Schulkindern N2 - No abstract available KW - Psychologie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43775 ER - TY - JOUR A1 - Hommers, Wilfried A1 - Steller, Max T1 - Zur Beeinflussung der Behandlungsbereitschaft von jugendlichen Strafgefangenen durch die "Experimenter-Subject"-Methode N2 - Durch BeDbachtungen und Beurteilungen wurde die Durchführbarkeit und Wirksamkeit einer MethDde zur Beeinflussung der Behandlungsbereitschaft bei 30 jugendlichen Strafgefangenen unter zwei VDllzugsbedingungen geprüft. Die MethDde erwies sich bei dieser Stichprobe als durchführbar und erschien darüber hinaus allenfalls in der Anfangsphase geeignet, therapeutische KDntakte bei Therapieunwilligen anzubahnen. Milieutherapeutische Bedingungen im StrafvDllzug waren förderlich für die anfangs auftretenden pO'sitiven Effekte. N2 - The E/licacy 0/ "Experimenter-Subject"-Method on Therapy Motivation 0/ Juvenile Delinquents The practicability and efficacy Df a clinical methDd tD increase therapy mDtivatiDn Df 30 juvenile delinquents living under tWD cDnditiDns Df imprisDnment was examined by DbservatiDn and rating methDds. The clinical methDd turned DUt to be practicable with this delinquent grDup, and seemed tO' be suitable fDr preparatiDn to therapy contacts, but O'nly in the beginning. Milieutherapeutical cDnditiDns Df imprisO'nment spDnSDr the revealing pDsitive effects in the beginning. KW - Kinderpsychologie KW - Kinderpsychiatrie Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-43757 ER - TY - JOUR A1 - Spring, Herbert A1 - Krohne, Georg A1 - Franke, Werner W. A1 - Scheer, Ulrich A1 - Trendelenburg, Michael F. T1 - Homogeneity and heterogeneity of sizes of transcriptional units and spacer regions in nucleolar genes of Acetabularia N2 - The arrangement of genes of precursor molecules for ribosomal RNA (pre-rRNA) in primary nuclei from two green algae species, Acetabularia mediterranea and A. major, has been analyzed in an electron microscope study. The pattern of transcriptional units in individual strands of nucleolar chromatin was investigated using spread and positively stained preparations. The rDNA pattern is not uniform but differs in different strands. The predominant type of nucleolar chromatin exhibits a high degree of homogeneity in the sequence of matrix units (intercepts covered with fibrilst hat contain the pre-rRNA) and fibril-free spacer intercepts. Substantial differences, however, are observed between the patterns in different strands. In addition, there is evidence in some strands for intraaxial heterogeneity of both spacer and matrix units. The following major types can be distinguished: type la, ca. 2 micrometer long matrix units, extremely short spacer intercepts in A. mediterranea (ca. 1 micrometer long ones in A. major), completely homogeneous distribution; type Ib, as type la but with intercalated, isolated, significantly shorter and/or longer matrix units; type lIa, matrix unit sizes as in type la, but much longer spacer intercepts, high degree of homogeneity; type Ill, largely heterogeneous arrangements of matrix and spacer units of varying sizes. The matrix unit data are compared with the sizes of pre-rRNA as determined by polyacrylamide gelelectrophoresis under denaturing and non-denaturing conditions. The findings are discussed in relation to recent observations in amphibia and insects and with respect to current concepts of the species-specificity of rDNA arrangements. Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-41398 ER - TY - JOUR A1 - Franke, Werner W. A1 - Scheer, Ulrich A1 - Trendelenburg, Michael F. A1 - Spring, Herbert A1 - Zentgraf, Hanswalter T1 - Absence of nucleosomes in transcriptionally active chromatin N2 - The ultrastructure of twO kinds of transcription ally active chromatin, the lampbrush chromosome loops and the nucleoli from amphibian oocytes and primary nuclei of the green alga Acetabularia, has been examined after manual isolation and dispersion in low salt media of slightly alkaline pH using various electron microscopic staining techniques (positive staining, metal shadowing, negative staining, preparation on positively charged films, etc.) and compared with the appearance of chromatin from various somatic cells (hen erythrocytes, rat hepatocytes, ClIltured murine sarcoma cells) prepared in parallel. While typical nucleosomes were revealed with all the techniques for chromatin from the latter three cell system, no nucleosomes were identified in either the lampbrush chromosome structures or the nucleolar chromatin. Nucleosomal arrays were absent not only in maximally fibril-covered matrix units but also in fibril-free regions between transcriptional complexes, including the apparent spacer intercepts between different transcriptional units. Moreover, comparisons of the length of the repeating units of rDNA in the transcribed state with those determined in the isolated rDNA and with the lengths of the first stable product of rDNA transcription, the pre-rRNA, demonstrated that the transcribed rDNA was not significantly shortened and/or condensed but rather extended in the transcriptional units. Distinct granules of about nucleosomal size which were sometimes found in apparent spacer regions as well as within matrix units of reduced fibril density were shown not to represent nucleosomes since their number per spacer unit was not inversely correlated with the length of the specific unit and also on the basis of their resistance to treatment with the detergent Sarkosyl NL-30. It is possible to structurally distinguish between transcriptionally active chromatin in which the DNA is extended in a non-nucleosomal form of chromatin and condensed, inactive chromatin within the typical nucleosomal package. The characteristic extended structure of transcriptionally active chromatin is found not only in the transcribed genes but also in non-transcribed regions within or between ("spacer") transcriptional units as well as in transcriptional units that are untranscribed amidst transcribed ones and/or have been inactivated for relatively short time. It is hypothesized that activation of transcription involves a transition from a nucleosomal to an extended chromatin organisation and that this structural transition is not specific for single "activated" genes but may involve larger chromatin regions, including adjacent untranscribed intercepts. KW - Cytologie KW - Chromatin structure KW - nucleosomes KW - transcription KW - electron microscopy Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-40646 ER - TY - JOUR A1 - Scheer, Ulrich A1 - Kartenbeck, Jürgen A1 - Trendelenburg, Michael F. A1 - Stadler, Joachim A1 - Franke, Werner W. T1 - Experimental disintegration of the nuclear envelope: evidence for pore-connecting fibrils N2 - The disintegration of the nuclear envelope has been examined in nuclei and nuclear envelopes isolated from amphibian oocytes and rat liver tissue, using different electron microscope techniques (ultrathin sections and negatively or positively stained spread preparations). Various treatments were studied, including disruption by surface tension forces, very low salt concentrations, and non ionic detergents such as Triton X-lOO and Nonidet P-40. The high local stability of the cylinders of nonmembranous pore complex material is emphasized. As progressive disintegration occurred in the membrane regions, a network of fibrils became apparent which interconnects the pore complexes and is distinguished from the pore complexassociated intranuclear fibrils. This network might correspond to an indistinct lamella, about 15 - 20 nm thick, located at the level of the inner nuclear membrane, which is recognized in thin sections to bridge the interpore distances. With all disintegration treatments a somewhat higher susceptibility of the outer nuclear membrane is notable, but a selective removal does not take place. Final stages of disintegration are generally characterized by the absence of identifiable, membrane- like structures. Analysis of detergent-treated nuclei and nuclear membrane fractions shows almost complete absence of lipid components but retention of significant amount of glycoproteins with a typical endomembrane-type carbohydrate pattern. Various alternative interpretations of these observations are discussed. From the present observations and those of Aaronson and Blobel (1,2), we favor the notion that threadlike intrinsic membrane components are stabilized by their attachment to the pore complexes, and perhaps also to peripheral nuclear structures, and constitute a detergent-resistant, interpore skeleton meshwork. Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-39735 ER - TY - JOUR A1 - Franke, Werner W. A1 - Scheer, Ulrich A1 - Spring, Herbert A1 - Trendelenburg, Michael F. A1 - Krohne, G. T1 - Morphology of transcriptional units of rDNA: evidence for transcription in apparent spacer intercepts and cleavages in the elongating nascent RNA N2 - Several types of "irregular" structures in the arrangement of lateral fibrils were noted in electron microscopic preparations of transcriptionally active nucleolar chromatin from various plant and animal cells. Such forms include: I. Disproportionately long lateral fibrils which occur either as individual fibrils or in groups; 2. "Prelude complexes" and other arrangements of lateral fibrils in apparent spacer intercepts; 3. Thickening of the rDNA chromatin axis at the starting end of pre-rRNA matrix units; 4. Extremely long matrix units , the length of which exceeds that of the rDNA (double-strand) sequence complementary to the specific pre-rRN A (for abbreviations see text). In addition, the stability of high molecular weight RNAs contained in the nucleolar ribonucleoproteins during the preparation for electron microscopy was demonstrated by gel electrophoresis. The observations indicate that the morphological starting point of a pre-rRNA matrix unit is not necessarily identical with the initiation site for synthesis of pre-rRNA, but they rather suggest that the start of the transcriptional unit is located at least O.2-D.8 JLm before the matrix unit and that parts of the "apparent spacer" are transcribed. It is proposed that the pre-rRN A molecules do not represent the primary product of rDNA transcription but rather relatively stable intermediate products that have already been processed during transcription. Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-39681 ER - TY - JOUR A1 - Klitzing, K. von A1 - Becker, Charles R. T1 - Far infrared photoconductivity of residual acceptors in pure tellurium N2 - The photoconductivity of both undeformed and deformed Te samples has been investigated at liquid He temperature by means of a Fourier spectrometer. Three peaks were usually found in the spectra of undeformed samples at 11, 24 and 46 cm\(^{-1}\). These are shown to be due to three different chemical impurities. The deformed samples are characterized by additional structure at higher frequencies. Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-31278 ER - TY - JOUR A1 - Trendelenburg, Michael F. A1 - Scheer, Ulrich A1 - Zentgraf, Hanswalter A1 - Franke, Werner W. T1 - Heterogeneity of spacer lengths in circles of amplified ribosomal DNA of two insect species, Dytiscus marginalis and Acheta domesticus N2 - No abstract available Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-33055 ER - TY - JOUR A1 - Ruhe, Ernstpeter T1 - Nouvelle critique und Strukturalismus N2 - No abstract available KW - Romanische Sprachen KW - Literatur KW - Geschichte Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-32324 SN - 3-87452-263-6 ER - TY - JOUR A1 - Scheer, Ulrich A1 - Trendelenburg, Michael F. A1 - Franke, Werner W. T1 - Regulation of transcription of genes of ribosomal RNA during amphibian oogenesis: a biochemical and morphological study N2 - Natural changes in the transcription of rRNA genes were studied in nucleoli from three oogenic stages of the newt Triturus alpestris with electron microscope, autoradiographic, and biochemical techniques. From determinations of the uridine triphosphate pool sizes and [3H]uridine uptake, phosphorylation, and incorporation into 28S and 18S rRNAs in vivo it was estimated that the rate of rRNA synthesis was about 0.01% in previtellogenic oocytes and 13% in mature oocytes when compared to midvitellogenesis. Spread preparations of nucleoli showed significant morphological changes in the transcriptional complexes. The total number of lateral fibrils, i.e., ribonucleoproteins containing the nascent rRNA precursor, were drastically decreased in stages of reduced synthetic activity. This indicates that rRNA synthesis is regulated primarily at the level of transcription. The resulting patterns of fibril coverage of the nucleolar chromatin axes revealed a marked heterogeneity. On the same nucleolar axis occurred matrix units that were completely devoid of lateral fibrils, matrix units that were almost fully covered with lateral fibrils, and various forms of matrix units with a range of lateral fibril densities intermediate between the two extremes. Granular particles that were tentatively identified as RNA polymerase molecules were not restricted to the transcription l complexes. They were observed, although less regularly and separated by greater distances, in untranscribed spacer regions as well as in untranscribed gene intercepts. The results show that the pattern of transcriptional control of rRNA genes differs widely in different genes, even in the same genetic unit. Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-32814 ER - TY - JOUR A1 - Scheer, Ulrich A1 - Franke, Werner W. A1 - Trendelenburg, Michael F. A1 - Spring, Herbert T1 - Classification of loops of lampbrush chromosomes according to the arrangement of transcriptional complexes N2 - The arrangement of transcriptional units in the loops of lampbrush chromosomes from oocyte nuclei of urodele amphibia and from primary nuclei of the green alga Acetabularia have been studied in the electron microscope using spread preparations. Loops with different patterns of arrangement of matrix units (i.e. to a first approximation, transcriptional units) can be distinguished: (i) loops consisting of one active transcriptional unit; (ii) loops containing one active transcriptional unit plus additional fibril-free, i.e. apparently untranscribed, intercepts that may include 'spacer' regions; (iii) loops containing two or more transcriptional units arranged in identical or changing polarities, with or without interspersed apparent spacer regions. Morphological details of the transcriptional complexes are described. The observations are not compatible with the concept that one loop reflects one and only one transcriptional unit but, rather, lead to a classification of loop types according to the arrangement of their transcriptional units. We propose that the lampbrush chromosome loop can represent a unit for the coordinate transcription of either one gene or a set of several (different) genes. Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-32822 ER - TY - JOUR A1 - Ruhe, Ernstpeter T1 - Le Professeur Taranne oder: Comment utiliser ses névroses N2 - No abstract available Y1 - 1976 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-32434 ER -