TY  - JOUR
A1  - Mostovaya, Ira M.
A1  - Grooteman, Muriel P.C.
A1  - Basile, Carlo
A1  - Davenport, Andrew
A1  - de Roij van Zuijdewijn, Camiel L.M.
A1  - Wanner, Christoph
A1  - Nubé, Menso J.
A1  - Blankestijn, Peter J.
T1  - High convection volume in online post-dilution haemodiafiltration: relevance, safety and costs
JF  - Clinical Kidney Journal
N2  - Increasing evidence suggests that treatment with online post-dilution haemodiafiltration (HDF) improves clinical outcome in patients with end-stage kidney disease, if compared with haemodialysis (HD). Although the primary analyses of three large randomized controlled trials (RCTs) showed inconclusive results, post hoc analyses of these and previous observational studies comparing online post-dilution HDF with HD showed that the risk of overall and cardiovascular mortality is lowest in patients who are treated with high-volume HDF. As such, the magnitude of the convection volume seems crucial and can be considered as the ‘dose’ of HDF. In this narrative review, the relevance of high convection volume in online post-dilution HDF is discussed. In addition, we briefly touch upon some safety and cost issues.
KW  - convection volume
KW  - costs
KW  - hemodiafiltration
KW  - mortality
KW  - safety
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-149814
VL  - 8
IS  - 4
ER  -