TY  - JOUR
A1  - Soundararajan, Manonmani
A1  - Marincola, Gabriella
A1  - Liong, Olivia
A1  - Marciniak, Tessa
A1  - Wencker, Freya D. R.
A1  - Hofmann, Franka
A1  - Schollenbruch, Hannah
A1  - Kobusch, Iris
A1  - Linnemann, Sabrina
A1  - Wolf, Silver A.
A1  - Helal, Mustafa
A1  - Semmler, Torsten
A1  - Walther, Birgit
A1  - Schoen, Christoph
A1  - Nyasinga, Justin
A1  - Revathi, Gunturu
A1  - Boelhauve, Marc
A1  - Ziebuhr, Wilma
T1  - Farming practice influences antimicrobial resistance burden of non-aureus staphylococci in pig husbandries
JF  - Microorganisms
N2  - Non-aureus staphylococci (NAS) are ubiquitous bacteria in livestock-associated environments where they may act as reservoirs of antimicrobial resistance (AMR) genes for pathogens such as Staphylococcus aureus. Here, we tested whether housing conditions in pig farms could influence the overall AMR-NAS burden. Two hundred and forty porcine commensal and environmental NAS isolates from three different farm types (conventional, alternative, and organic) were tested for phenotypic antimicrobial susceptibility and subjected to whole genome sequencing. Genomic data were analysed regarding species identity and AMR gene carriage. Seventeen different NAS species were identified across all farm types. In contrast to conventional farms, no AMR genes were detectable towards methicillin, aminoglycosides, and phenicols in organic farms. Additionally, AMR genes to macrolides and tetracycline were rare among NAS in organic farms, while such genes were common in conventional husbandries. No differences in AMR detection existed between farm types regarding fosfomycin, lincosamides, fusidic acid, and heavy metal resistance gene presence. The combined data show that husbandry conditions influence the occurrence of resistant and multidrug-resistant bacteria in livestock, suggesting that changing husbandry practices may be an appropriate means of limiting the spread of AMR bacteria on farms.
KW  - non-aureus staphylococci
KW  - NAS
KW  - alternative pig farming
KW  - antimicrobial resistance
KW  - one-health approach
KW  - intervention strategies
KW  - livestock-associated staphylococci
KW  - organic farming
KW  - pig farming methods
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-312750
SN  - 2076-2607
VL  - 11
IS  - 1
ER  -