TY  - JOUR
A1  - Togninalli, Matteo
A1  - Seren, Ümit
A1  - Meng, Dazhe
A1  - Fitz, Joffrey
A1  - Nordborg, Magnus
A1  - Weigel, Detlef
A1  - Borgwardt, Karsten
A1  - Korte, Arthur
A1  - Grimm, Dominik G.
T1  - The AraGWAS Catalog: a curated and standardized Arabidopsis thaliana GWAS catalog
JF  - Nucleic Acids Research
N2  - The abundance of high-quality genotype and phenotype data for the model organism Arabidopsis thaliana enables scientists to study the genetic architecture of many complex traits at an unprecedented level of detail using genome-wide association studies (GWAS). GWAS have been a great success in A. thaliana and many SNP-trait associations have been published. With the AraGWAS Catalog (https://aragwas.1001genomes.org) we provide a publicly available, manually curated and standardized GWAS catalog for all publicly available phenotypes from the central A. thaliana phenotype repository, AraPheno. All GWAS have been recomputed on the latest imputed genotype release of the 1001 Genomes Consortium using a standardized GWAS pipeline to ensure comparability between results. The catalog includes currently 167 phenotypes and more than 222 000 SNP-trait associations with P < 10\(^{-4}\), of which 3887 are significantly associated using permutation-based thresholds. The AraGWAS Catalog can be accessed via a modern web-interface and provides various features to easily access, download and visualize the results and summary statistics across GWAS.
KW  - model organism
KW  - genotype
KW  - phenotype
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-158727
VL  - 46
IS  - D1
ER  -