TY  - JOUR
A1  - Linz, Christian
A1  - Faber, Julian
A1  - Schmid, Reiner
A1  - Kunz, Felix
A1  - Böhm, Hartmut
A1  - Hartmann, Stefan
A1  - Schweitzer, Tilmann
T1  - Using a 3D asymmetry index as a novel form for capturing complex three-dimensionality in positional plagiocephaly
JF  - Scientific Reports
N2  - Positional plagiocephaly (PP) is the most common skull deformity in infants. Different classification systems exist for graduating the degree of PP, but all of these systems are based on two-dimensional (2D) parameters. This limitation leads to several problems stemming from the fact that 2D parameters are used to classify the three-dimensional (3D) shape of the head. We therefore evaluate existing measurement parameters and validate a newly developed 3D parameter for quantifying PP. Additionally, we present a new classification of PP based on a 3D parameter. 210 patients with PP and 50 patients without PP were included in this study. Existing parameters (2D and 3D) and newly developed volume parameters based on a 3D stereophotogrammetry scan were validated using ROC curves. Additionally, thresholds for the new 3D parameter of a 3D asymmetry index were assessed. The volume parameter 3D asymmetry index quantifies PP equally as well as the gold standard of 30° diagonal difference. Moreover, a 3D asymmetry index allows for a 3D-based classification of PP. The 3D asymmetry index can be used to define the degree of PP. It is easily applicable in stereophotogrammetric datasets and allows for comparability both intra- and inter-individually as well as for scientific analysis.
KW  - craniofacial orthodontics
KW  - physical examination
KW  - three-dimensional imaging
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-300427
VL  - 12
ER  - 
TY  - JOUR
A1  - Winter, Anna
A1  - Schulz, Stefan M.
A1  - Schmitter, Marc
A1  - Brands, Roman C.
A1  - Straub, Anton
A1  - Kübler, Alexander
A1  - Borgmann, Anna
A1  - Hartmann, Stefan
T1  - Oral-health-related quality of life in patients with medication-related osteonecrosis of the jaw: a prospective clinical study
JF  - International Journal of Environmental Research and Public Health
N2  - Medication-related osteonecrosis of the jaw (MRONJ) represents an adverse side effect of antiresorptive and antiangiogenic medications. It is associated with impaired quality of life, oral health, and oral function and can be classified into various stages. The purpose of this prospective clinical study is to evaluate the impact of stages I and II MRONJ on oral-health-related quality of life (OHRQoL) and related parameters. Patients’ OHRQoL, satisfaction with life, oral discomfort, and oral health were assessed using the German version of the Oral Health Impact Profile (OHIP-G49), visual analog scales (VAS), and Satisfaction with Life Scale (SWLS) at baseline (T0), 10 days (T1), and 3 months after treatment (T2) in 36 patients. Data were analyzed using Kolmogorov–Smirnov test, two-way mixed ANOVAs, and follow-up Mann–Whitney U tests. The impact of treatment effects on the original seven OHIP domain structures and the recently introduced four-dimensional OHIP structure were evaluated using linear regression analysis. Thirty-six patients received surgical MRONJ treatment. Before treatment, patients’ perceived OHRQoL, oral discomfort, oral health, and satisfaction with life were negatively affected by MRONJ. Surgical treatment significantly improved OHRQoL and related parameters (all p ≤ 0.012). This improvement was greater in patients with higher impairment at T0. OHRQoL and oral restrictions were still impaired after treatment in patients who needed prosthetic treatment. The four-dimensional structure revealed valuable information beyond the standard seven OHIP domains. Increased awareness of MRONJ risks and an interdisciplinary treatment approach for MRONJ patients are needed.
KW  - oral-health-related quality of life
KW  - satisfaction with life
KW  - oral health
KW  - medication-related osteonecrosis of the jaw
KW  - treatment benefit
KW  - OHIP-49
KW  - SWLS
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-288141
SN  - 1660-4601
VL  - 19
IS  - 18
ER  -