TY  - JOUR
A1  - Fröhlich, Ellen
A1  - Sassenrath, Claudia
A1  - Nadji-Ohl, Minou
A1  - Unteroberdörster, Meike
A1  - Rückriegel, Stefan
A1  - Brelie, Christian von der
A1  - Roder, Constantin
A1  - Forster, Marie-Therese
A1  - Schommer, Stephan
A1  - Löhr, Mario
A1  - Pala, Andrej
A1  - Goebel, Simone
A1  - Mielke, Dorothee
A1  - Gerlach, Rüdiger
A1  - Renovanz, Mirjam
A1  - Wirtz, Christian Rainer
A1  - Onken, Julia
A1  - Czabanka, Marcus
A1  - Tatagiba, Marcos Soares
A1  - Rohde, Veit
A1  - Ernestus, Ralf-Ingo
A1  - Vajkoczy, Peter
A1  - Gansland, Oliver
A1  - Coburger, Jan
T1  - Resilience in lower grade glioma patients
JF  - Cancers
N2  - Current data show that resilience is an important factor in cancer patients’ well-being. We aim to explore the resilience of patients with lower grade glioma (LGG) and the potentially influencing factors. We performed a cross-sectional assessment of adult patients with LGG who were enrolled in the LoG-Glio registry. By phone interview, we administered the following measures: Resilience Scale (RS-13), distress thermometer, Montreal Cognitive Assessment Test for visually impaired patients (MoCA-Blind), internalized stigmatization by brain tumor (ISBI), Eastern Cooperative Oncological Group performance status (ECOG), patients’ perspective questionnaire (PPQ) and typical clinical parameters. We calculated correlations and multivariate regression models. Of 74 patients who were assessed, 38% of those showed a low level of resilience. Our results revealed significant correlations of resilience with distress (p < 0.001, −0.49), MOCA (p = 0.003, 0.342), ECOG (p < 0.001, −0.602), stigmatization (p < 0.001, −0.558), pain (p < 0.001, −0.524), and occupation (p = 0.007, 0.329). In multivariate analyses, resilience was negatively associated with elevated ECOG (p = 0.020, β = −0.383) and stigmatization levels (p = 0.008, β = −0.350). Occupation showed a tendency towards a significant association with resilience (p = 0.088, β = −0.254). Overall, low resilience affected more than one third of our cohort. Low functional status is a specific risk factor for low resilience. The relevant influence of stigmatization on resilience is a novel finding for patients suffering from a glioma and should be routinely identified and targeted in clinical routine.
KW  - resilience
KW  - lower grade glioma
KW  - diffuse astrocytoma
KW  - oligodendroglioma
KW  - RS-13
KW  - distress
KW  - internalized stigmatization
KW  - ISBI
KW  - occupation
KW  - pain
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-297518
SN  - 2072-6694
VL  - 14
IS  - 21
ER  -