TY - JOUR A1 - Pauli, Paul A1 - Strian, F. A1 - Lautenbacher, S. A1 - Karlbauer, G. A1 - Hölzl, R. T1 - Emotionale Auswirkungen der autonomen Deafferentierung bei Diabetes-Neuropathie N2 - Bei 46 Typ-I-Diabetikern im Alter zwischen 15 und 44 Jahren wurden die Auswirkungen der viszeralen Deafferentierung bei autonomer Diabetesneuropathie auf körperliche Befindlichkeit und Emotionalität untersucht. Die Erfassung des Ausprägungsgrad der autonomen Neuropathie erfolgte mit vegetativen Funktionstest. Diabetiker ohne Neuropathie (N = 14), mit leichter Neuropathie (N = 23) und mit schwerer Neuropathie (N = 9) wurden miteinander verglichen. Gering ausgeprägte autonome Neuropathie führt zu vegetativen Funktionsstörungen, ist aber gleichzeitig mit einer verminderten Wahrnehmung körperlicher Beschwerden - erfaßt mit der Freiburger Beschwerdenliste - verbunden. Im Streß- und Copingverhalten (SCOPE) und in bestimmten Persönlichkeitsdimensionen (FPI) finden sich dabei Hinweise auf eine verminderte emotionale Reaktivität. Patienten mit fortgeschrittener autonomer Neuropathie haben zumeist ausgeprägte diabetische Folgekrankheiten (diabetische Retinopathie, Makro- und Mikroangiopathie etc.), scheinen aber die damit verbundenen körperlichen Beeinträchtigungen und emotionalen Belastungen nicht stärker als Diabetiker ohne Neuropathie wahrzunehmen. Die autonome Deafferentierung bei Diabetikern scheint somit sowohl zu einer gestörten Wahrnehmung körperlicher Beschwerden wie auch zu einer beeinträchtigten emotionalen Reaktionsfähigkeit zu führen. N2 - Bei 46 Typ-I-Diabetikern im Alter zwischen 15 und 44 Jahren wurden die Auswirkungen der viszeralen Deafferentierung bei autonomer Diabetesneuropathie auf körperliche Befindlichkeit und Emotionalität untersucht. Die Erfassung des Ausprägungsgrad der autonomen Neuropathie erfolgte mit vegetativen Funktionstest. Diabetiker ohne Neuropathie (N = 14), mit leichter Neuropathie (N = 23) und mit schwerer Neuropathie (N = 9) wurden miteinander verglichen. Gering ausgeprägte autonome Neuropathie führt zu vegetativen Funktionsstörungen, ist aber gleichzeitig mit einer verminderten Wahrnehmung körperlicher Beschwerden - erfaßt mit der Freiburger Beschwerdenliste - verbunden. Im Streß- und Copingverhalten (SCOPE) und in bestimmten Persönlichkeitsdimensionen (FPI) finden sich dabei Hinweise auf eine verminderte emotionale Reaktivität. Patienten mit fortgeschrittener autonomer The perception of visceral activity is impaired in diabetics with autonomie neuropathy. This should affect the perception of somatic complaints and the emotional state of these patients. The degree of auronomic neuropathy was examined with three physiological tests for autonomie functions. Differences were evaluated between diabetics without neuropathy (N = 14), with mild neuropathy (N = 23) and with severe neuropathy (N = 9). It was found that mild autonomie neuropathy is related to a small increase in somatic problems (resulting from diabetes). In spite of this, autonomie deafferentation leads to a de~rease in somatic complaints (Freiburger Beschwerden Liste (FBL» and to a reduction in emotionality (assessed with personality questionaires (SCOPE and FPI». Patients with severe autonomie neuropathy exhibit frequent somatic problems. The somatic complaints and the emotionality of these patients are comparable with diabetics without neuropathy. The results show that autonomie deafferentation in diabetics is related to a reduced perception of somatic complaints and a decrease in the emotionality of these patients. KW - Psychologie Y1 - 1989 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-55283 ER - TY - BOOK A1 - Pauli, Paul T1 - Ein psychophysiologisches Modell der Herzphobie : Empirische Bestätigung für einen Circulus-vitiosus-Prozeß zwischen kardialer Wahrnehmung, Angst und kardialer Aktivität N2 - No abstract available KW - Herzneurose KW - Physiologische Psychologie Y1 - 1990 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-46177 SN - 3-89073-491-X ER - TY - JOUR A1 - Pauli, Paul A1 - Hartl, Lydia A1 - Marquardt, Christian A1 - Stalmann, Henrica A1 - Strian, Friedrich T1 - Heartbeat and arrhythmia perception in diabetic autonomic neuropathy N2 - A comparative study of diabetics with autonomic neuropathy (N = 13) as against nonneuropathic diabetics (N = 16) and healthy control persons (N = 20) was carried out with respect 10 heart rate both at rest and under stress, frequency of cardiac arrhythmias in a 24-h ECG and accuracy of heartbeat and arrhythmia perception. In the subjects with diabetic autonomic neuropathy, the spontaneaus variability and stress-induced reactivity of the heart rate as weil as the number of tachycardic episodes were reduced, whereas the frequency of ventricular extrasystoles was somewhat increased. Impaired heartbeat perception and a complete Ioss of perception of arrhythmias as a consequence of neuropathic deafferentation could be demonstrated. Cardiac perception disordersalso playavital roJe in other clinical problems, e.g. silent myocardial infarction and Iack of awareness of hypoglycaemia in diabetes mellitus. KW - Psychologie Y1 - 1991 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-73599 ER - TY - JOUR A1 - Pauli, Paul A1 - Marquardt, Christian A1 - Hartl, Lydia A1 - Nutzinger, Detlef O. A1 - Hölzl, Rupert A1 - Strian, Friedrich T1 - Anxiety induced by cardiac perceptions in patients with panic attack: a field study N2 - In panic disorder bodily sensations appear to play an important role as a trigger for anxiety. In our psychophysiological model of panic attacks we postulate the following vicious circle: individuals with panic attacks perceive even quite small increases in heart rate and interpret these changes as being catastrophic. This elicits anxiety and a further increase in heart rate. To evaluate this model we conducted a field study of 28 subjects with panic attacks and 20 healthy controls. A 24 hr ambulatory ECG was recorded and the subjects were instructed to report any cardiac perceptions during this period and to rate the anxiety elicited by these perceptions. The incidence of cardiac perceptions was about the same in both groups, but only subjects with panic attacks reported anxiety associated with such perceptions. Analysis of the ECGs revealed that in both groups heart rate accelerations preceded cardiac perceptions. Following cardiac perceptions, the healthy controls showed a heart rate deceleration, whereas the subjects with panic attacks had a further acceleration. This heart rate increase after cardiac perceptions was positively related to the level of anxiety elicited by the perceptions. These results provide clear evidence in support of the vicious circle model of panic attacks. KW - Psychologie Y1 - 1991 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61334 ER - TY - JOUR A1 - Pauli, Paul A1 - Herschbach, P. A1 - Weiner, H. A1 - von Rad, M. T1 - Psychologische Faktoren der Non-Ulcer Dyspepsia (NUD) N2 - Given the absence of any demonstrable organic reason for non~ulcer dyspepsia. and the weil known fact, that the psyche inOuences stomach function, it is widely held, that psychological factors cause NUD. To now, studies are concerned with the psychopathology and personality of NUDpatients, their illness behaviour, and with the relation between stress and abdominal pain. A critical review of these studies revea1ed, that among the psycho1ogical variables majnly anxiety and illness behaviour seems to playa central role in NUD. However. future studjes should focus more on the distinction towards other funcüonal disorders and on the djfferentation within the heterogeneous group of NUD~ patients (especially with regard to physiological variables). Besides this, it seems rewarding to examine the so far seienlifidy neglected group of subjects with abdomina] pain, who do not contact a physician. N2 - Da organische Ursachen für die Non-Ulcer Dyspepsia nicht nachweisbar sind und außerdem bekannt ist, daß die Psyche einen wichtigen Einfluß auf die Magenfu nktion hat. werden häufig psychologische Faktoren als Ursache der NUD angesehen. Bisher liegen empirische Arbeiten über die Psychopathologie und Persönlichkeitsstruktur der NUD-Patienten. deren Krankheitsverhalten sowie über den Zusammenhang zwischen Streß und Magenbeschwerden vor. Eine kritische Sichtung dieser Arbeiten ergab, daß umer den psychologischen Variablen die Angst und das Krankheitsverhalten der NUD-Patienten eine besondere Rolle zu spielen scheinen. In zukünftigen Studien sollte außerdem mehr als bisher auf die Abgrenzung gegenüber anderen funktionellen Störungsbildern und auf eine bessere Differenzierung (u. a. hinsichtlich physiologischer Funktionsveränderungen) innerhalb der heterogenen Gruppe der NUD-Patienten geachtet werden. Lohnenswert erscheint es auch, die bisher noch gar nicht untersuchten Personen mit Magenbeschwerden, aber ohne Arztkomakt. genauer psychologisch zu untersuchen. KW - Psychologie KW - Psychosomatik KW - Non-ulcer dyspepsia KW - functional dyspepsia KW - psychology Y1 - 1992 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-80202 ER - TY - JOUR A1 - Pauli, Paul A1 - Schwenzer, Michael A1 - Brody, Stuart A1 - Rau, Harald A1 - Birbaumer, Niels T1 - Hypochondriacal attitudes, pain sensitivity, and attentional bias N2 - The relation between hypochondriacal attitudes, thermal pain threshold, and attentional bias toward pain was examined in a non-clinical population (N = 28). Attentional bias was operationalized with a concentration-performance test, which subjects performed while connected to a pain stimulator. Subjects were informed that they would receive a painful stimulus during the second part of the test, while the first part was introduced as pain-free. The pain stimulus was never applied during the test phase. The expectancy of a forthcoming pain stimulus reduced the performance of high hypochondriacal subjects in both parts of the test. Low hypochondriacal subjects, on the other hand, displayed significantly better performance in the first, pain-free compared to the second, pain-related part of the test. Thermal pain thresholds were assessed at four measuring sites (thenar, neck, collar-bone, abdomen), but no relations with hypochondriasis sum scores and locus of pain stimulation were found. A stepwise multiple regression of pain threshold by individual Illness Attitude Scales (IAS) led to 66% of the variance being explained by the scales ‘concern about pain’, ‘worry about illness’, and ‘disease phobia’. Results are discussed in terms of amplifying somatic style, preoccupation with or attentional bias toward bodily symptoms, and experimental induction of a hypochondriacal state. Y1 - 1993 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-32617 ER - TY - JOUR A1 - Pauli, Paul A1 - Rau, Harald A1 - Zhuang, Ping A1 - Brody, Stuart A1 - Birbaumer, Niels T1 - Effects of smoking on thermal pain threshold in deprived and minimally-deprived habitual smokers N2 - This study examined the antinociceptive effects of smoking in nine habitual smokers under deprived (12 h) and minimally-deprived (< 30min) conditions. Pain threshold for thermal stimuli, heart rate, blood pressure and ratings of mood, arousal, dominance and well-being were assessed before and after smoking a cigarette. Overall, smoking affected all measured variables in the expected direction, leading to increased physiological activity, elevated pain threshold and improved mood. However, most of these effects depended on the deprivation status of the subjects, such that smoking after deprivation increased pain threshold whereas smoking after minimal deprivation did not. Pain threshold before smoking was the same for both groups. Deprived subjects had lower pre-smoke diastolic blood pressure, heart rate, and arousal levels, which rose to equal minimally-deprived subjects scores after smoking. KW - Pain threshold ; Smoking ; Nicotine ; Acute tolerance ; Deprivation ; Psychophysiologicat measures Y1 - 1993 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-32607 ER - TY - JOUR A1 - Pauli, Paul A1 - Lutzenberger, W. A1 - Rau, H. A1 - Birbaumer, N. A1 - Rickard, T. C. A1 - Yaroush, R. A. A1 - Bourne, L. E. J. T1 - Brain potentials during mental arithmetic: effects of extensive practice and problem difficulty N2 - Recent behavioral investigations indicate that the processes underlying mental arithmetic change systematically with practice from deliberate, conscious calculation to automatic, direct retrieval of answers from memory [Bourne, L.E.Jr. and Rickard, T.C., Mental calculation: The development of a cognitive skill, Paper presented at the Interamerican Congress of Psychology, San Jose, Costa Rica, 1991; Psychol. Rev., 95 (1988) 492-527]. Results reviewed by Moscovitch and Winocur [In: The handbook of aging and cognition, Erlbaum, Hillsdale, NJ, 1992, pp. 315-372] suggest that consciously controlled processes are more dependent on frontal lobe function than are automatic processes. It is appropriate, therefore to determine whether transitions in the locus of primary brain activity occur with practice on mental calculation. In this experiment, we examine the relationship between characteristics of event-related brain potentials (ERPs) and mental arithmetic. Single-digit mental multiplication problems varying in difficulty (problem size) were used, and subjects were trained on these problems for four sessions. Problem-size and practice effects were reliably found in behavioral measures (RT). The ERP was characterized by a pronounced late positivity after task presentation followed by a slow wave, and a negativity during response indication. These components responded differentially to the practice and problem-size manipulations. Practice mainly affected topography of the amplitude of positivity and offset latency of slow wave, and problem-size mainly offset latency of slow wave and pre-response negativity. Fronto-central positivity diminished from session to session, and the focus of positivity centered finally at centro-parietal regions. This finding suggests that frontal lobe processing is necessary as long as task performance is not automatized, while automatized arithmetic processing requires parietal brain activity only. The pre-response negativity observed in the first session and during more difficult tasks is assumed to reflect excitatory preparatory processes, which could be associated with activation of calculation strategies. KW - Psychologie KW - Mental arithmetic KW - Event-related potential KW - Practice KW - Automatization KW - Problem size Y1 - 1994 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-61345 ER -