TY  - JOUR
A1  - Schartl, Manfred
A1  - Kneitz, Susanne
A1  - Volkoff, Helene
A1  - Adolfi, Mateus
A1  - Schmidt, Cornelia
A1  - Fischer, Petra
A1  - Minx, Patrick
A1  - Tomlinson, Chad
A1  - Meyer, Axel
A1  - Warren, Wesley C.
T1  - The piranha genome provides molecular insight associated to its unique feeding behavior
JF  - Genome Biology and Evolution
N2  - The piranha enjoys notoriety due to its infamous predatory behavior but much is still not understood about its evolutionary origins and the underlying molecular mechanisms for its unusual feeding biology. We sequenced and assembled the red-bellied piranha (Pygocentrus nattereri) genome to aid future phenotypic and genetic investigations. The assembled draft genome is similar to other related fishes in repeat composition and gene count. Our evaluation of genes under positive selection suggests candidates for adaptations of piranhas’ feeding behavior in neural functions, behavior, and regulation of energy metabolism. In the fasted brain, we find genes differentially expressed that are involved in lipid metabolism and appetite regulation as well as genes that may control the aggression/boldness behavior of hungry piranhas. Our first analysis of the piranha genome offers new insight and resources for the study of piranha biology and for feeding motivation and starvation in other organisms.
KW  - whole-genome sequencing
KW  - genome annotation
KW  - comparative genomics
KW  - RNA-seq transcriptome
KW  - energy homeostasis
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-202218
VL  - 11
IS  - 8
ER  - 
TY  - JOUR
A1  - Du, Kang
A1  - Wuertz, Sven
A1  - Adolfi, Mateus
A1  - Kneitz, Susanne
A1  - Stöck, Matthias
A1  - Oliveira, Marcos
A1  - Nóbrega, Rafael
A1  - Ormanns, Jenny
A1  - Kloas, Werner
A1  - Feron, Romain
A1  - Klopp, Christophe
A1  - Parrinello, Hugues
A1  - Journot, Laurent
A1  - He, Shunping
A1  - Postlethwait, John
A1  - Meyer, Axel
A1  - Guiguen, Yann
A1  - Schartl, Manfred
T1  - The genome of the arapaima (Arapaima gigas) provides insights into gigantism, fast growth and chromosomal sex determination system
JF  - Scientific Reports
N2  - We have sequenced the genome of the largest freshwater fish species of the world, the arapaima. Analysis of gene family dynamics and signatures of positive selection identified genes involved in the specific adaptations and unique features of this iconic species, in particular it’s large size and fast growth. Genome sequences from both sexes combined with RAD-tag analyses from other males and females led to the isolation of male-specific scaffolds and supports an XY sex determination system in arapaima. Whole transcriptome sequencing showed that the product of the gland-like secretory organ on the head surface of males and females may not only provide nutritional fluid for sex-unbiased parental care, but that the organ itself has a more specific function in males, which engage more in parental care.
KW  - Genome
KW  - Genomics
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-201333
VL  - 9
ER  -