TY  - JOUR
A1  - Zinner, Christoph
A1  - Sperlich, Billy
A1  - Wahl, Patrick
A1  - Mester, Joachim
T1  - Classification of selected cardiopulmonary variables of elite athletes of different age, gender, and disciplines during incremental exercise testing
JF  - SpringerPlus
N2  - Incremental exercise testing is frequently used as a tool for evaluating determinants of endurance performance. The available reference values for the peak oxygen uptake \((VO_{2peak})\), % of \(VO_{2peak}\) , running speed at the lactate threshold \((v_{LT})\), running economy (RE), and maximal running speed \((v_{peak})\) for different age, gender, and disciplines are not sufficient for the elite athletic population. The key variables of 491 young athletes (age range 12–21 years; 250 males, 241 females) assessed during a running step test protocol \((2.4 m s^{−1} ; increase 0.4 m s^{−1}  5 min^{−1})\) were analysed in five subgroups, which were related to combat-, team-, endurance-, sprint- and power-, and racquet-related disciplines. Compared with female athletes, male athletes achieved a higher \(v_{peak}\) (P = 0.004). The body mass, lean body mass, height, abs. \(VO_{2peak} (ml min^{−1})\), rel. \(VO_{2peak} (ml kg^{−1}  min^{−1})\), rel. \(VO_{2peak} (ml min^{−1}  kg^{−0.75})\), and RE were higher in the male participants compared with the females (P < 0.01). The % of \(VO_2\) at \(v_{LT}\) was lower in the males compared with the females (P < 0.01). No differences between gender were detected for the \(v_{LT}\) (P = 0.17) and % of \(VO_2\) at \(v_{LT}\) (P = 0.42). This study is one of the first to provide a broad spectrum of data to classify nearly 500 elite athletes aged 12–21 years of both gender and different disciplines.
KW  - performance
KW  - data
KW  - competition
KW  - reference values
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-126275
VL  - 4
IS  - 544
ER  - 
TY  - THES
A1  - Kirchgäßner, Christoph
T1  - Bestimmung von Referenzbereichen für die Schilddrüsenhormonparameter TSH, fT3 und fT4 bei Neugeborenen, Kindern und Jugendlichen
T1  - Reference values of thyroid hormones TSH, fT3 and fT4 for newborns, children and teenagers
N2  - Neubestimmung der Referenzbereiche für die Schilddrüsenhormonparameter TSH, fT3 und fT4 für Kinder von der Geburt bis zum 18. Lebensjahr mittels Immulite Immunoassay.
N2  - Creation of new reference values for thyroid hormones TSH, fT3 and fT4 for children using the Immulite immunoassay
KW  - Schilddrüse
KW  - Thyreotropin
KW  - Thyroxin
KW  - Normalwert
KW  - fT3
KW  - fT4
KW  - Immulite
KW  - Immunoassay
KW  - Referenzbereiche
KW  - reference values
KW  - thyroid
KW  - TSH
KW  - fT3
KW  - fT4
Y1  - 2010
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-54090
ER  - 
TY  - THES
A1  - Eichhorn, Eva-Maria
T1  - Analyse der ontogenetischen Veränderungen in B-Zell-Subpopulationen im Kindes- und Erwachsenenalter
T1  - Analysis of ontogenetic changes in B-cell-subpopulations in infancy and adulthood
N2  - B-Lymphozyten sind die zellulären Träger der humoralen Immunität des adaptiven Immunsystems. Sie spielen eine wesentliche Rolle bei Immundefekten und Autoimmunprozessen. In dieser Arbeit sollen Entwicklungsveränderungen der peripheren B-Zell-Populationen von der Kindheit bis zum Erwachsenenalter charakterisiert und altersabhängige Referenzwerte generiert werden. In einer durchflusszytometrischen Analyse wurden dafür sowohl relative als auch absolute Häufigkeiten für naive B-Zellen, Gedächtnis-B-Zellen, Transitionalzellen, Plasmablasten und CD21 low CD38 low B-Zellen untersucht. Die meisten B-Zell-Subpopulationen zeigen spezifische ontogenetische Veränderungen.
N2  - B-cells are the cellular components of the humoral defense of the adaptive immune system. They play an important role in immunodeficiency or autoimmune diseases. In this work developmental changes in peripheral B-cell-populations have been characterizied from infancy to adulthood in order to define age-dependent reference values. Using a Flow cytometric approach frequencies and absolute counts of naive B-cells, memory B-cells, transitional B-cells, plasmablasts and CD21 low CD38 low B-cells have been analyzied. Most of B-cell-subpopulations underlie developmental changes during ontogeny.
KW  - Durchflusscytometrie
KW  - Lymphozyt
KW  - Immundefekt
KW  - B-Zellen
KW  - Referenzwerte
KW  - CVID
KW  - Ontogenetik
KW  - b-lymphocytes
KW  - reference values
KW  - CVID
KW  - ontogeny
Y1  - 2011
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-72429
ER  -