TY - JOUR A1 - Schmitz, Barbara T1 - Tradition und (Er)Neuerung. Die Rede von Gott in jüdisch-hellenistischer Literatur JF - Theologische Literaturzeitung N2 - God as King is one of the metaphors that have been handed down in the biblical literature for centuries. In the Hellen­istic period talk about God as king again undergoes a change that is the conse-quence of the Hellenistic kingdom as it evolved in its specific form after the death of Alexander. The conceptual implications of the Hellenistic kingdom for talk about God is shown by reference to the epithets: the king as ἐπιφανής (»Epiphanes«), as σωτήρ (»Savior«), as εὐεργέτης (»benefactor«) and as κτίστης (»Founder«). How those epithets have affected talk of God as king is demonstrated by reference to the original Greek writings of the LXX and connected with the question of God as παντοκράτωρ (»pantocrator«). KW - Gott KW - Hellenistisch-jüdische Literatur Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-151292 UR - http://www.thlz.com/artikel/18775/ VL - 141 IS - 7/8 ER - TY - JOUR A1 - Pötters, Wilhelm ED - Hornung, Christoph ED - Lambrecht, Gabriella-Maria ED - Sendner, Annika T1 - \(Spagna\) in Dantes poetischer Kosmologie JF - Kommunikation und Repräsentation in den romanischen Kulturen. Festschrift für Gerhard Penzkofer N2 - Verstreut über den ganzen Text der Göttlichen Komödie kommen verschiedene geographische Namen vor, die sich auf Spanien beziehen. In mehreren dieser Fälle hat Dante die im wörtlichen Schriftsinn verwendeten toponymischen Zeichen als Elemente hermetisch wirkender Aussagen und damit offenbar als Indizien einer verborgenen Botschaft konzipiert. Zum Nachweis dieser These soll in den folgenden Betrachtungen erkundet werden, welche Funktion den im wissenschaftlichen Weltbild des Dichters verankerten spanischen Land- und Städtenamen in der Komposition des Epos zukommt. Damit möchte ich meinem Kollegen und Freund Gerhard Penzkofer für die vielen anregenden Gespräche danken, die wir – in den Jahren der gemeinsamen Tätigkeit in der Würzburger Romanistik – vor allem über cosas de España führen konnten. Da der vorliegende Band unter den von seiner Lehre inspirierten Leitbegriffen Kommunikation und Repräsentation steht, bietet es sich am Schluss an, die beiden Konzepte mit den vom Dichter diskutierten Termini sensus litteralis und sensus allegoricus in Beziehung zu setzen. KW - Dante KW - Spanien KW - Dante, Alighieri KW - Dante, Alighieri : Divina commedia KW - Göttliche Komödie KW - Spanien Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-152077 UR - https://www.avm-verlag.de/detailview?no=5477-055 SN - 9783954770557 PB - AVM.edition CY - München ER - TY - JOUR A1 - Drenckhahn, Detlev T1 - Vorkommen des Atlantischen Wildkohls (Brassica oleracea L. subsp. oleracea) an den Kreidefelsen der Ostseeinsel Rügen, Deutschland T1 - Occurrence of Atlantic wild cabbage (Brassica oleracea L. subsp. oleracea) at the limestone cliffs of the baltic island of Rügen, Germany JF - Forum Geobotanicum N2 - Der Atlantische Wildkohl (Brassica oleracea L. subsp. oleracea) wächst auf den Küstenfelsen des Atlantiks und der Nordsee zwischen Nord-Spanien, Schottland und der Nordseeinsel Helgoland. 2001 wurde auch ein Vorkommen des Wildkohls an den Kreidefelsen der Ostseeinsel Rügen nachgewiesen, das aus ungefähr 50 Individuen besteht. Die Pflanzen unterscheiden sich phänotypisch nicht von Wildpflanzen der Atlantikküsten. Da alle verbreiteten Kultursorten des Gemüsekohls genetisch sehr eng mit dem Atlantischen Kohl verwandt sind, vom dem sie höchstwahrscheinlich abstammen, wird die Frage erörtert, ob eine spontane Rückverwandlung (Rückkreuzung) von in die Natur entwichenen Kultursorten in den Wildkohl-Phänotyp möglich ist. Dieses wird als wenig wahrscheinlich angesehen. Dagegen ist Introgression zwischen Kultursorten und Wildsorten gut belegt. Die Frage nach einer möglichen Hybridisierung von Grünkohl mit Pflanzen vom Wildkohlphänotyp oder mit anderen Kultursorten an der Kreideküste der dänischen Ostseeinsel Seeland wird anhand eigener Beobachtungen erörtert. Die dortige Population besteht offensichtlich aus verwilderten Kulturkohlhybriden, die sich deutlich von den Wildpflanzen Rügens unterscheiden. Das neue Vorkommen des Atlantischen Wildkohls in der westlichen Ostsee kann im Zusammenhang mit der Ostausbreitung anderer atlantischer Sippen im Rahmen des Klimawandels gesehen werden. N2 - The distribution area of the Atlantic wild cabbage (Brassica oleracea L. subsp. oleracea), hitherto known to be restricted to atlantic coastal cliffs between Northern Spain, Scotland and Helgoland, has expanded this century eastwards to the limestone cliffs of the island of Rügen in the Baltic Sea. The population size is about 50 individuals which are morphologically indistinguishable from Atlantic wild cabbage. The possibility is addressed whether the Rügen population might be derived by backcrossing and naturalization of escaped cultured Brassica oleracea varieties. Genetic studies have shown that the main cultured varieties grown today are closely related to Atlantic wild cabbage from which these varieties were most likely raised. Spontaneous reversal from cultured varieties to the atlantic wild phenotype has often been claimed but not been convincingly demonstrated in the literature and it is considered unlikely that such a full reversal would occur in the absence of crosspollination (introgression) with wild type cabbages. However, introgression of cultured varieties with wild types or naturalization of escaped cultured cole varieties to a more archaic phenotype has been reported. Such an introgression or naturalization process is currently taking place at the limestone coast of Zealand/Denmark. As documented and described in this study, the wild growing coles of Zealand look like descendents of kale and (headed) cabbage and differ considerably from the population of Rügen and Helgoland. The currently observed eastward extension of the atlantic range of wild Brassica oleracea into the Baltic Sea can be interpreted as a more general phenomenon of eastward expansion of the distribution area of other atlantic species in the course of climate warming. KW - Brassica oleracea KW - Atlantischer Wildkohl KW - Kohl Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-142963 UR - http://www.forum-geobotanicum.net/articles/vol_7-2016/drenckhahn_brassica/drenckhahn_brassica_oleracea.pdf SN - 1867-9315 VL - 7 ER - TY - JOUR A1 - Wörsdörfer, Anna Isabell T1 - Vom ‘bon sauvage’ zum französischen Ritter par excellence. Die ‘Matière de Bretagne’ als Streitobjekt konkurrierender Erinnerungskulturen in Jean-Pierre Claris de Florians Mittelalternovelle Bliombéris (1784). JF - promptus - Würzburger Beiträge zur Romanistik N2 - While French Enlightenment seems philosophically dominated by a pejorative idea of the medieval past as the ‘Dark Ages’, this is only one conception among others. This article focuses on a different, a positive, representation of the Middle Ages in eighteenth-century literature, analyzing the chivalric novella Bliombéris (1784) by Jean-Pierre Claris de Florian. On the one hand, the eponymous hero is considered a ‘noble savage’ who develops into an ideal knight by education and successful learning – two central ideas of the Enlightenment period. On the other hand, the study shows how the medieval topic of the Matière de Bretagne, exclusively required by English literature for a long time, is finally regained by the French and is reintegrated into their national memory. KW - Bliombéris Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-139518 SN - 2510-2613 VL - 1 ER - TY - JOUR A1 - Uzunkaya, Hümeyra T1 - Präpositionalphrasen mit der Präposition de im Französischen – Struktur und Realisierungsformen JF - promptus - Würzburger Beiträge zur Romanistik N2 - This paper investigates the linguistic properties of prepositional phrases containing de in the French language by means of a comprehensive compilation of possible formal realizations, for which examples are provided out of a chosen sample text. Special attention will be paid to the most frequently-cited formal realization, namely the combination of a preposition and a noun phrase. The corresponding forms will be divided into two classes, one with nominal phrases containing a phonetically realized or at least an underlying determiner, and one with nominal phrases in which no determiner is assumed to occur. This distinction will shed light on some of the difficulties that can arise in the assignment of the elements to either category due to the special interaction between the preposition de and the French system of determiners. KW - Präpositionalphrasen KW - Französisch Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-139506 SN - 2510-2613 VL - 1 ER - TY - JOUR A1 - Sorrenti, Elisa T1 - Zweitspracherwerb und Interlanguage. Eine empirische Untersuchung zur deutschen Wortstellung bei L1-Italienisch-Sprechern mit L2-Deutsch JF - promptus - Würzburger Beiträge zur Romanistik N2 - Much research on first language (L1) acquisition carried out in the last decades has proven that language acquisition is based on a biological endowment, the language faculty, which is triggered by the exposure to linguistic data. The language acquisition process undergoes similar stages in the same time span, independently of the specific language. Non-native acquisition differs from L1 acquisition, as the speaker already has an internal grammar with all parameters set. Transfer should therefore take place, bringing the learner to analyse the new input according to the properties of the L1, but a reanalysis is possible because of the availability of UG (Schwartz/Sprouse 1996). This article explores a syntactic domain, namely the properties of the functional categories constraining the verb position in main and subordinate clauses, by means of empirical data from Italian L1-speakers acquiring German as a second language (L2). It will be shown that the interlanguage grammars reflect properties of L1 and that resetting can be achieved, although optionality still exists and full convergence to the target language cannot be guaranteed. KW - Zweitspracherwerb Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-139498 SN - 2510-2613 VL - 1 ER - TY - JOUR A1 - Hettmann, Sandra T1 - «Explotan las imágenes y un altoparlante con su lengua». Surrealistische Dis/Kontinuitäten bei Luciana Romano: Bebilderungen im Gedichtraum durch Fotoästhetik und Dynamiken des Wortbildes JF - promptus - Würzburger Beiträge zur Romanistik N2 - This article seeks to analyse the volume of poems Vapor de foto (2006) written by the young contemporary poet Luciana Romano from Buenos Aires. Romano is also an activist of the politically engaged artist collective Etcétera… founded in the late nineties. Her poetry reveals a certain correlation with the aesthetics of the actions and interventions developed by Etcétera… in the streets and public spaces not only of Argentina but also of Europe. Furthermore, the creation of Vapor de foto is based on the collective’s experiences and practices. Using a methodological approach that combines close reading and a cultural and socio-critical focus, several poems will be exemplarily analysed in order to examine the interrelation between Romano’s style of writing and her activism. Assuming that her poetry, as well as the work of Etcétera…, belongs to a postdictatorial contemporary aesthetics characterized by the complex interplay between dadaistic and surrealistic dis/continuities, this article will focus on the analysis of different forms of relations between text and image. KW - Luciana Romano Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-139473 SN - 2510-2613 VL - 1 ER - TY - JOUR A1 - Hertrampf, Marina Ortrud M. T1 - De la Mère Patrie à «l’amère-patrie». Désiré Razafinjatos literarisches Bild der französischen 'Kolonialheimat' vor und nach der Unabhängigkeit Madagaskars JF - promptus - Würzburger Beiträge zur Romanistik N2 - French-Madagascan colonial history is full of dark chapters. After Madagascar’s independence the French general public forgot the country very quickly. In Malagasies collective memory, the wounds of colonial injustice are still open even if they are generally considered as fady (‘tabooʼ). Désiré Razafinjato is the first Malagasy author writing in French who dares to approach the difficult relations between Malagasy-French and indigenous Malagasy as well as between indigenous Francophiles and indigenous anti-French nationalists. In his tale «Tahiry. From Madagascar to the Algerian djebel, the bitter-fatherland», the narrator speaks about the painful loss of any fatherland for all those Malagasy who during the War of Algeria got involved as French soldiers. Indeed, it is the sad history of the despoliation of an ideal Motherland on the French side and of the refusal of membership in an ancestral fatherland on the Malagasy side. What remains for those ancient French-Malagasy combatants is the feeling of a ‘bitter-fatherlandʼ and the feeling of living in ‘between everywhereʼ in some kind of ‘non-fatherlandʼ. KW - Désiré Razafinjato Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-139461 SN - 2510-2613 VL - 1 ER - TY - JOUR A1 - Cunha, Conceição T1 - captar – cap(i)tar, facto – fato: Variation und Wandel bei Plosivsequenzen im Portugiesischen JF - promptus - Würzburger Beiträge zur Romanistik N2 - The present study is concerned with the production and perception of the stop consonant clusters /pt/ and /kt/ as well as CVC-Sequences /pVt/ and /kVt/ in European and Brazilian Portuguese (EP and BP, respectively). European and Brazilian Portuguese have the same syllable structure (Bisol 1999: 731, Mateus/d’Andrade 2000: 39), but are postlexically affected by contrary phenomena. After the occurence of phonological processes such as vowel reduction and deletion in European clusters and vowel epenthesis in Brazilian consonant clusters, the difference between lexical consonant clusters and CVC-sequences would be diminished in both varieties, so that EP would realize both as CC, while BP would realize both as CVC. In order to test whether clusters and CVC-sequences can be distinguished in production and perception, we discuss a physiological experiment and a perceptual study with participants of both varieties. The results show less overlap in BP than in EP. The reason for which is seen in the perception of intervocalic epenthetic elements even in lexical clusters in BP and more consonant clusters in EP. KW - Plosivsequenzen KW - Portugiesisch Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-139454 SN - 2510-2613 VL - 1 ER - TY - JOUR A1 - Lange (geb. Hilt), Lydia T1 - Dominus contulit splendorem (Idt 10,4) : das Motiv der Schönheit im Buch Iudith N2 - The use of the motif of beauty in the Vulgate on the one hand and in LXX/HS 151 on the other hand reveals a conspicuous difference. While Judith just makes herself beautiful (Jdt 10,2-4 LXX/ Hs 151) and her original God-given beauty is a precondition (Jdt 8,7), in the Vulgate it is God who gives her beauty. So beauty is not an inherent part of Iudith's characterization anymore, to be seen in line with integrity and blessing by God as it was the case for the LXX and Hs 151. In the Vulgate beauty loses its significance, because Iudith is only given beauty in order to awake the hostile general Holofernis' desire, so that he will fall. While Holofernis is going to succumb to his evil desire, Iudith sets herself morally apart because of the contrary, her chastity, and because of that she is not initially characterized as beautiful, but as decent (elegans, Jdt 8,7). In Idt 10,4 virtue rather than desire is assigned to her. Because of her chaste way of life God predestines Iudith for the salvation, and this is what he makes her beautiful for. Therefore chastity is a central and specific virtue in the Iudith story in Vg. Iudith represents everything that Jerome describes as a Godfearing life, and therefore she is rewarded by God. Tue variants in Idt 8,7 and Idt 10,4 in comparison to the other text versions show St. Jerome's typical profile of the Iudith story and aim at this message. N2 - Die Verwendung des Motivs der Schönheit in Vg einerseits und in LXX/ Hs 151 andererseits zeigt eine auffällige Differenz. Während Judit sich in Jdt 10,2-4 LXX / Hs 151 nur schön macht und ursprünglich bereits als Gott gegebene Voraussetzung schön war (Jdt 8,7), lässt Idt 10,4 Vg sie durch das Handeln Gottes erst schön werden. Schönheit ist damit in der Vg nicht mehr länger fester Bestandteil der Figurencharakterisierung Iudiths und auf einer Linie mit innerer Rechtschaffenheit und göttlichem Segen zu sehen, wie es noch für LXX und Hs 151 galt. In der Vg verliert die Schönheit vielmehr an Bedeutung, denn Iudith erhält sie einzig und allein, um die Begierde des feindlichen Feldherrn zu wecken, damit dieser dadurch zu Fall kommt. Während Holofernis seiner negativ bewerteten Begierde unterliegen wird, ist es Iudith, die sich durch das Gegenteil, durch ihre „Keuschheit" (castitas), moralisch abhebt und darum zunächst nicht als schön, sondern als „anständig" (elegans) charakterisiert wird (Idt 8,7). In Idt 10,4 wird ihr dann die Tugend (virtus) statt der „Begierde" (libido) zugeordnet. Aufgrund ihrer keuschen Lebensweise wird Iudith von Gott zur rettenden Tat bestimmt, der sie zur Verwirklichung derselben schön macht. Die Keuschheit ist es, die den Leserinnen und Lesern, wie in der praefatio beschrieben, als nachahmungswürdiges Vorbild dienen soll. Iudith verkörpert damit all das, was in den hieronymianischen Schriften vielfach als rechtes Leben vor Gott beschrieben ist und wird dafür von Gott belohnt. Die Abänderungen in Idt 8 7 und Idt 10 ,4 im Vergleich zu den anderen Textfassungen zeigen das hieronymianische Profil der Iudith-Erzählung und zielen auf diese Botschaft hin. KW - Bibel. Judit KW - Schönheit KW - Septuaginta KW - Vulgata Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-137652 ER - TY - JOUR A1 - Drenckhahn, Detlev T1 - Morphologie und Jahreszyklus von Ficaria calthifolia Rchb. – eine neu etablierte Sippe in Deutschland T1 - Morphology and annual cycle of Ficaria calthifolia Rchb. – a recently established species for Germany JF - Forum Geobotanicum N2 - Ficaria calthifolia (diploide Form, Typ1) wurde kürzlich nord-westlich des geschlossenen südosteuropäischen Verbreitungsgebiet auch in Deutschland gefunden, nämlich in Würzburg (2006) und an Elbedeichen in Brandenburg (2014) und Sachsen (2015). Ficaria calthifolia ist durch das Fehlen von verlängerten mehrgliedrigen Stängeln und die Abwesenheit von Brutknollen in den Blattachseln gekennzeichnet. Die 1–2 (3) Stängel von Ficaria calthifolia verbleiben überwiegend im Boden (hypogäisch), können aber im Laufe der Anthese aus dem Boden hervorwachsen. Die gestielten Laubblätter setzen sich aus Grundblättern und einer Rosette von bis zu 8 Stängelblättern pro Stängel zusammen. Letztere entspringen aus dem terminalen Stängelknoten (Stängelblatt-rosette). In Würzburg kommen zwei Populationen von Ficaria calthifolia vor, diploide Typ1-Pflanzen und triploide Typ2-Pflanzen. Letztere sind robuster, besitzen größere Blüten (bis 4 cm) und entwickeln nur vereinzelte reife Nüsschen. Pflanzen mit höherem Ploidiegrad (wahrscheinlich pentaploid, Typ3) wurden auch gefunden. Etwa 60% der 3 bis 8 Blütenstiele von Typ1-Pflanzen besitzt kein Stängelblatt, der Rest einen Knoten mit 1 bis 2 (3) Hochblättern. Die Zahl der Kronblätter beträgt 8 (vereinzelt 9), die durchschnittliche Zahl reifer, eiförmiger Nüsschen pro Fruchtstand beträgt 7 (Würzburg) / 14 (Elbe) (maximal 26). Aus vom Rhizom abgebrochenen und im Mai gepflanzten Speicherknollen keimten im Spätherbst desselben Jahrs neue Pflanzen. Der Jahreszyklus des Wurzelsystems wird beschrieben. Durch spontane Ablösungen einzelner Speicherknollen findet eine vegetative Vermehrung statt. Neben Nüsschen wären abgebrochene Speicherknollen für die Fernansiedlung der Sippe an Elbe (u.a. Verschleppung durch Hochwasser) und Main (Verschleppung durch Schiffe und andere Vektoren) ausreichend. N2 - Ficaria calthifolia (typical diploid form, type1) has recently been discovered to grow outside its southeastern European distribution area also in Germany, namely in Northern Bavaria (Würzburg) and at dikes of the river Elbe in Brandenburg and Saxony. Ficaria calthifolia is distinguished from Ficaria verna by the absence of both elongated multisegmental stems and axillary tubers (bulbils). The 1–2 (3) short stems of Ficaria calthifolia remain mostly underground and may extend during anthesis few cm above ground. Leaves form a rosette-like cluster consisting of ground leaves (directly arising from the rhizome) and a rosette of up to 8 stem-leaves that emanate from the single (terminal) node of the short stems. The majority of flower stalks are leafless (true pedicles) but about 40% contain a single, a pair or rarely a triplet of petiolate leaves. The number of petals is 8 (9). Diploid Ficaria calthifolia is fertile with average 7 (Würzburg) to 14 nutlets (Elbe population) per head (maximum 26). In Würzburg also triploid plants (type2) were encountered being more robust than diploid plants with larger flowers, larger blades and largely abortive nutlets. A small population of plants (type3) with higher numbers of chromosomes (probably pentaploid) was also found. Plants intermediate between Ficaria calthifolia and Ficaria verna are readily distinguished by axillary tubers at stem leaves. Tubers removed from rhizome of Ficaria calthifolia and planted in soil in May gave rise to new plants sprouting in late autumn. Annual cycle of the root system is described. Spontaneous shedding of tubers from rhizome appears to be a regular mechanism of vegetative proliferation of Ficaria calthifolia. Thus, accidental displacement not only of nutlets but also of tubers via rivers (i.e. river Elbe) or by other (anthropogenic) vectors could be sufficient for north-westward expansion of the distribution area. KW - Ficaria calthifolia KW - Morphotype KW - Ficaria verna KW - Karyotyp KW - morphotypes KW - karyotypes Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-136225 UR - http://www.forum-geobotanicum.net/articles/vol_7-2016/drenckhahn_ficaria/drenckhahn_ficaria_calthifolia.pdf SN - 1867-9315 VL - 7 ER - TY - JOUR A1 - Wilhelm, Gernot T1 - Probleme der hethitischen Chronologie JF - Orientalische Literaturzeitung N2 - No abstract available. KW - Hethiter KW - Geschichte Y1 - 1991 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128499 VL - 86 IS - 5/6 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Lange, Hartwig A1 - Bentlage, Anke A1 - Sheldrick, William S. A1 - Ernst, Ludger T1 - 2.2.5.5-Tetraorganyl-1.4-dioxa-2.5-disilacyclohexane/2,2,5,5-Tetraorganyl-1,4-dioxa-2,5-disilacyclohexanes JF - Zeitschrift für Naturforschung B N2 - The 2,2,5,5-tetraorganyl-1,4-dioxa-2,5-disilacyclohexanes 2a-2c were prepared by condensation of the corresponding (hydroxymethyl)diorganylsilanes 1 a-1 c. The constitution of the heterocycles was confirmed by elemental analyses, cryoscopic measurements, mass spectrometry, and NMR-spectroscopic \((^1H, ^{13}C)\) investigations. The molecular structure of 2 b was determined by X-ray diffraction analysis. KW - 1,4-Dioxa-2 KW - 5-disila-cyclohexane ring system KW - synthesis KW - structure Y1 - 1983 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128423 VL - 38 IS - 2 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Lange, Hartwig A1 - Sheldrick, William S. A1 - Lambrecht, Günter A1 - Moser, Ulrich A1 - Mutschler, Ernst T1 - Sila-Pharmaka, 31. Mitt. [1] Synthese, Struktur und pharmakologische Eigenschaften von Diphenyl(2-piperidinoethoxymethyl)silanol und seinem Kohlenstoff-Analogon T1 - Sila-Pharmaca, 31 th Communication [1] Synthesis, Structure, and Pharmacological Properties of Diphenyl(2-piperidinoethoxymethyl)silanol and its Carbon Analogue JF - Zeitschrift für Naturforschung B N2 - In the course of systematic investigations on sila-substituted parasympatholytics the diphenyl(2-aminoethoxymethyl)silanols 3b and 4b (and its carbon analogue 4a) were synthesized and characterized by their physical and chemical properties. In the solid state 4a and 4b form strong O-H---N hydrogen bonds, which are intramolecular (4a) and intermolecular (4b), respectively. 4a and 4b were found to be weak antimuscarinic agents (4b >4a) and strong papaverine-like spasmolytics (4a ≈4b). KW - antimuscarinic and papaverine-like activity KW - sila-substitution KW - crystal and molecular structure Y1 - 1983 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128410 VL - 38 IS - 6 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Linoh, Haryanto A1 - Attar-Bashi, Moayad T. A1 - Sheldrick, William S. A1 - Ernst, Ludger A1 - Niedner, Roland A1 - Frohnecke, Joachim T1 - Sila-Pharmaka, 26. Mitt. [1] Darstellung und Eigenschaften potentiell curarewirksamer Silicium-Verbindungen, III T1 - Sila-Pharmaca, 26th Communication [1] Preparation and Properties of Silicon Compounds with Potential Curare-Like Activity, III JF - Zeitschrift für Naturforschung B N2 - The potentially curare-like silicon compounds 8a- 8f were synthesized and investigated with respect to their structure-activity relationships. The conformations of the compounds in the solid state and in solution were studied by X-ray diffraction analysis (8a- 8e) and IR NMR spectroscopy (8a- 8f), respectively. The muscle relaxing properties of 8a- 8f were investigated on the mouse. The observed structure-activity relationships are not in accordance with the classical "14 Å model" for neuromuscular blocking agents. KW - structure-activity relationships KW - X-ray KW - curare-lik activity KW - silicon compounds KW - conformational anaylses Y1 - 1982 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128402 VL - 37 IS - 11 ER - TY - JOUR A1 - Tacke, R. A1 - Strecker, M. A1 - Sheldrick, W. S. A1 - Heeg, E. A1 - Berndt, B. A1 - Knapstein, K. M. T1 - Sila-Pharmaka, 14. Mitt. Darstellung und Eigenschaften sowie Kristall-und Molekülstruktur von Sila-Difenidol JF - Zeitschrift für Naturforschung B N2 - Sila-difenidol (6b), a sila-analogue of the drug difenidol (6a), was synthesized according to Scheme 1. 6b and its new precursors 3 and 5 were characterized by their physical and chemical properties, and their structures confirmed by elementary analyses, 1H NMR and mass spectroscopy. 6 b crystallizes orthorhombic \(P2_12_12_1\) with a = 11.523(1), b = 14.366(4), c = 11.450(1) Å, Z = 4, \(D_{ber} = 1.14 gcm^{-3}\). The structure was refined to R = 0.050 for 1897 reflexions. A strong nearly linear intramolecular O-H···N hydrogen bond of 2.685 Å is observed. The anticholinergic, histaminolytic and musculotropic spasmolytic activities of 6 a and 6 b are reported. KW - sila-difenidol KW - syntheses KW - crystal structure KW - molecular structure KW - biological activity Y1 - 1979 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128391 VL - 34 IS - 9 ER - TY - JOUR A1 - Tacke, R. A1 - Bentlage, A. A1 - Sheldrick, W. S. A1 - Ernst, L. A1 - Towart, R. A1 - Stoepel, K. T1 - Sila-Pharmaka, 24. Mitt. [1]. Sila-Analoga von Nifedipin-ähnlichen 4-Aryl-2.6-dimethyl-1.4-dihydropyridin- 3.5-dicarbonsäure-dialkylestern, II. T1 - Sila-Drugs, 24th Communication [1]. Sila-Analogues of Nifedipine-Like Dialkyl 4-Aryl-2,6-dimethyl-1,4-dihydropyridine- 3,5-dicarboxylates, II. JF - Zeitschrift für Naturforschung B N2 - In the course of systematic studies on sila-substituted drugs the nifedipine-like 1.4-dihydropyridine derivatives 4a, 4b and 4c were prepared and investigated with respect to sila-substitution effects. By X-ray diffraction analyses 4a, 4b and 4c were found to be isostructural. The C/Si-analogues exhibit similar spasmolytic activities (in vitro, guinea pig ileum), comparable with that of nifedipine. However, the compounds differ substantially in their in vivo activity, as measured by the antihypertensive effect on the renal-hypertensive rat. The experimental results are discussed with respect to the carbon/silicon exchange. KW - sila-analogues of Nifedipine derivatives KW - X-ray KW - pharmacological activity KW - structure-activity relationships Y1 - 1982 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128381 VL - 37 IS - 4 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Linoh, Haryanto A1 - Stumpf, Burghard A1 - Abraham, Wolf-Rainer A1 - Kieslich, Klaus A1 - Ernst, Ludger T1 - Mikrobiologische Umwandlung von Silicium-Verbindungen: Enantioselektive Reduktion von Acetessigsäure-(trimethylsilylalkyl)estern und deren Carba-Analoga T1 - Microbiological Transformation of Silicon Compounds: Enantioselective Reduction of Trimethylsilylalkyl Acetoacetates and their Carba-Analogues JF - Zeitschrift für Naturforschung B N2 - The trimethylsilylalkyl acetoacetates 1 b and 2 b as well as their carba analogues 1 a and 2 a have been reduced microbiologically by Kloeckera corticis (ATCC 20109), leading to the corresponding ( + )-3(S)-hydroxybutanoates 3b, 4b, 3a, and 4a. The enantiomeric purity was found to be 80% (3a, 3b, 4b) and 65% (4a), respectively. The reduction of lb and 2b is - to our knowledge - the first example for a controlled microbiological transformation of organosilicon substrates. KW - enantioselective reduction KW - microbiological transformation KW - silicon compounds Y1 - 1983 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128304 VL - 38 IS - 5 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Link, Matthias A1 - Bentlage-Felten, Anke A1 - Zilch, Harald T1 - Zum thermischen Verhalten einiger Kohlensäure[(methylphenylsilyl)methyl]ester-Derivate T1 - On the Thermal Behaviour of Some (Methylphenylsilyl)methyl Carbonate Derivatives JF - Zeitschrift für Naturforschung B N2 - The synthesis and the thermal behaviour of the (methylphenylsilyl)methyl carbonates \(CH_3(C_6H_5)Si(H)CH_2OC(O)X (6: X = OCH_3; 7: X = Cl; 8: X = N(CH_3)_2)\) is described. 8 rearranges in toluene solution at 100 °C quantitatively to give the carbam oyloxysilane \(C_6H_5(CH_3)_2SiOC(O)N(CH_3)_2\) (11), whereas neat 6 and 7 at 135 °C undergo quantitative formation of \(C_6H_5(CH_3)_2SiOCH_3\) (12) and \(C_6H_5(CH_3)_2SiCl\) (13), respectively. The formation of 12 and 13 is explained by a rearrangement reaction (by analogy to the rearrangement of 8), follow ed by a decarboxylation. The thermally induced transformations 6 →12, 7 →13, and 8 →11 were found to be first-order reactions with half-lifes of ~2.6 h (135 °C, neat), ~4.5 h (135 °C, neat), and ~3.7 h (100 °C, in toluene), respectively. KW - decarboxylation KW - (Methylphenylsilyl)methyl carbonates KW - rearrangement KW - dimethylphenylsilyl carbonates Y1 - 1985 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128293 VL - 40 IS - 7 ER - TY - JOUR A1 - Tacke, Reinhold A1 - Niederer, Reinhold T1 - Sila-Pharmaka, 9. Mitt. [1] Darstellung und Eigenschaften potentiell curarewirksamer Silicium-Verbindungen, I T1 - Sila-Drugs, 9th Communication [1] Preparation and Properties of Silicon Compounds with Potential Curare-Like Activity, I JF - Zeitschrift für Naturforschung B N2 - Organosilicon compounds 8, 9 and 10 with potential curare-like action and their precursors 0, 6 and 7 were synthesized for the first time. 0-10 were characterized by their physical and chemical properties, and their structures were confirmed by analyses, IH NMR and mass spectroscopy (only for 0-7). The pharmacological and toxicological data of 8, 9 and 10 are reported. KW - curare-like activity KW - toxicological properties KW - pharmacological properties KW - silicon compounds Y1 - 1978 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-128277 VL - 33 IS - 4 ER -