TY - JOUR A1 - Linsenmair, Karl Eduard T1 - Vogelzwerge des Waldes N2 - No abstract available Y1 - 1964 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-44632 ER - TY - JOUR A1 - Linsenmair, Karl Eduard T1 - Ritter und Türmchen: aus dem Leben der Reiterkrabbe N2 - No abstract available Y1 - 1964 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-44643 ER - TY - JOUR A1 - Thielcke, Gerhard A1 - Linsenmair, Karl Eduard T1 - Zur geographischen Variation des Gesanges des Zilpzalps, Phylloscopus collybita, in Mittel- und Südwesteuropa mit einem Vergleich des Gesanges de Fitis, Phylloscopus trochilus N2 - No abstract available Y1 - 1963 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-44657 ER - TY - JOUR A1 - Linsenmair, Karl Eduard A1 - Jander, R. T1 - Das "Entspannungsschwimmen" von Velia und Stenus N2 - No abstract available Y1 - 1963 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-44663 ER - TY - JOUR A1 - Linsenmair, Karl Eduard T1 - Gefangenschafts-Bruterfahrungen mit Rotkehlchen, Schwarzkelchen und Sommergoldhähnchen N2 - No abstract available Y1 - 1961 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-44675 ER - TY - JOUR A1 - Schumann, Frank A1 - Steinborn, Michael B. A1 - Kürten, Jens A1 - Cao, Liyu A1 - Händel, Barbara Friederike A1 - Huestegge, Lynn T1 - Restoration of attention by rest in a multitasking world: theory, methodology, and empirical evidence JF - Frontiers in Psychology N2 - In this work, we evaluate the status of both theory and empirical evidence in the field of experimental rest-break research based on a framework that combines mental-chronometry and psychometric-measurement theory. To this end, we (1) provide a taxonomy of rest breaks according to which empirical studies can be classified (e.g., by differentiating between long, short, and micro-rest breaks based on context and temporal properties). Then, we (2) evaluate the theorizing in both the basic and applied fields of research and explain how popular concepts (e.g., ego depletion model, opportunity cost theory, attention restoration theory, action readiness, etc.) relate to each other in contemporary theoretical debates. Here, we highlight differences between all these models in the light of two symbolic categories, termed the resource-based and satiation-based model, including aspects related to the dynamics and the control (strategic or non-strategic) mechanisms at work. Based on a critical assessment of existing methodological and theoretical approaches, we finally (3) provide a set of guidelines for both theory building and future empirical approaches to the experimental study of rest breaks. We conclude that a psychometrically advanced and theoretically focused research of rest and recovery has the potential to finally provide a sound scientific basis to eventually mitigate the adverse effects of ever increasing task demands on performance and well-being in a multitasking world at work and leisure. KW - rest breaks KW - attention restoration theory KW - cognitive resources KW - mental fatigue KW - ego depletion KW - multitasking KW - energy management KW - motivated cognition Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-267913 SN - 1664-1078 VL - 13 ER - TY - JOUR A1 - Houben, Roland A1 - Ebert, Marlies A1 - Hesbacher, Sonja A1 - Kervarrec, Thibault A1 - Schrama, David T1 - Merkel Cell Polyomavirus Large T Antigen is Dispensable in G2 and M-Phase to Promote Proliferation of Merkel Cell Carcinoma Cells JF - Viruses N2 - Merkel cell carcinoma (MCC) is an aggressive skin cancer frequently caused by the Merkel cell polyomavirus (MCPyV), and proliferation of MCPyV-positive MCC tumor cells depends on the expression of a virus-encoded truncated Large T antigen (LT) oncoprotein. Here, we asked in which phases of the cell cycle LT activity is required for MCC cell proliferation. Hence, we generated fusion-proteins of MCPyV-LT and parts of geminin (GMMN) or chromatin licensing and DNA replication factor1 (CDT1). This allowed us to ectopically express an LT, which is degraded either in the G1 or G2 phase of the cell cycle, respectively, in MCC cells with inducible T antigen knockdown. We demonstrate that LT expressed only in G1 is capable of rescuing LT knockdown-induced growth suppression while LT expressed in S and G2/M phases fails to support proliferation of MCC cells. These results suggest that the crucial function of LT, which has been demonstrated to be inactivation of the cellular Retinoblastoma protein 1 (RB1) is only required to initiate S phase entry. KW - Merkel cell polyomavirus KW - large T antigen KW - cell cycle KW - Merkel cell carcinoma Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-218171 SN - 1999-4915 VL - 12 IS - 10 ER - TY - JOUR A1 - Lüke, Carina A1 - Ritterfeld, Ute A1 - Liszkowski, Ulf T1 - In bilinguals' hands: identification of bilingual, preverbal infants at risk for language delay JF - Frontiers in Pediatrics N2 - Studies with monolingual infants show that the gestural behavior of 1–2-year-olds is a strong predictor for later language competencies and, more specifically, that the absence of index-finger pointing at 12 months seems to be a valid indicator for risk of language delay (LD). In this study a lack of index-finger pointing at 12 months was utilized as diagnostic criterion to identity infants with a high risk for LD at 24 months in a sample of 42 infants growing up bilingually. Results confirm earlier findings from monolinguals showing that 12-month-olds who point with the extended index finger have an advanced language status at 24 months and are less likely language delayed than infants who only point with the whole hand and do not produce index-finger points at 12 months. KW - gesture KW - pointing KW - language delay KW - language acquisition KW - bilingualism Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-276639 SN - 2296-2360 VL - 10 ER - TY - JOUR A1 - Matuz, Tamara A1 - Birbaumer, Niels A1 - Hautzinger, Martin A1 - Kübler, Andrea T1 - Psychosocial adjustment to ALS: a longitudinal study JF - Frontiers in Psychology N2 - For the current study the Lazarian stress-coping theory and the appendant model of psychosocial adjustment to chronic illness and disabilities (Pakenham, 1999) has shaped the foundation for identifying determinants of adjustment to ALS. We aimed to investigate the evolution of psychosocial adjustment to ALS and to determine its long-term predictors. A longitudinal study design with four measurement time points was therefore, used to assess patients' quality of life, depression, and stress-coping model related aspects, such as illness characteristics, social support, cognitive appraisals, and coping strategies during a period of 2 years. Regression analyses revealed that 55% of the variance of severity of depressive symptoms and 47% of the variance in quality of life at T2 was accounted for by all the T1 predictor variables taken together. On the level of individual contributions, protective buffering, and appraisal of own coping potential accounted for a significant percentage in the variance in severity of depressive symptoms, whereas problem management coping strategies explained variance in quality of life scores. Illness characteristics at T2 did not explain any variance of both adjustment outcomes. Overall, the pattern of the longitudinal results indicated stable depressive symptoms and quality of life indices reflecting a successful adjustment to the disease across four measurement time points during a period of about two years. Empirical evidence is provided for the predictive value of social support, cognitive appraisals, and coping strategies, but not illness parameters such as severity and duration for adaptation to ALS. The current study contributes to a better conceptualization of adjustment, allowing us to provide evidence-based support beyond medical and physical intervention for people with ALS. KW - ALS KW - coping KW - depression KW - quality of life KW - longitudinal assessment Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-190208 SN - 1664-1078 VL - 6 IS - 1197 ER - TY - JOUR A1 - Strack, Fritz A1 - Pauli, Paul A1 - Weyers, Peter T1 - Editorial: Emotion and Behavior JF - Frontiers in Psychology N2 - No abstract available. KW - emotions KW - behavior KW - approach KW - avoidance KW - impulsive behavior Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-190177 SN - 1664-1078 VL - 7 IS - 313 ER - TY - JOUR A1 - Eder, Andreas B. A1 - Rothermund, Klaus A1 - Hommel, Bernhard T1 - Commentary: Contrasting motivational orientation and evaluative coding accounts: on the need to differentiate the effectors of approach/avoidance responses JF - Frontiers in Psychology N2 - A commentary on "Contrasting motivational orientation and evaluative coding accounts: on the need to differentiate the effectors of approach/avoidance responses" by Kozlik, J., Neumann, R., and Lozo, L. (2015). Front. Psychol. 6:563. doi: 10.3389/fpsyg.2015.00563 KW - evaluative coding account KW - motivational systems KW - approach-avoidance KW - stimulus-response compatibility KW - Theory of Event Coding (TEC) Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-190141 SN - 1664-1078 VL - 7 IS - 163 ER - TY - JOUR A1 - Widder, A. A1 - Backhaus, J. A1 - Wierlemann, A. A1 - Hering, I. A1 - Flemming, S. A1 - Hankir, M. A1 - Germer, C.-T. A1 - Wiegering, A. A1 - Lock, J. F. A1 - König, S. A1 - Seyfried, F. T1 - Optimizing laparoscopic training efficacy by ’deconstruction into key steps’: a randomized controlled trial with novice medical students JF - Surgical Endoscopy N2 - Background Simulator training is an effective way of acquiring laparoscopic skills but there remains a need to optimize teaching methods to accelerate learning. We evaluated the effect of the mental exercise ‘deconstruction into key steps’ (DIKS) on the time required to acquire laparoscopic skills. Methods A randomized controlled trial with undergraduate medical students was implemented into a structured curricular laparoscopic training course. The intervention group (IG) was trained using the DIKS approach, while the control group (CG) underwent the standard course. Laparoscopic performance of all participants was video-recorded at baseline (t0), after the first session (t1) and after the second session (t2) nine days later. Two double-blinded raters assessed the videos. The Impact of potential covariates on performance (gender, age, prior laparoscopic experience, self-assessed motivation and self-assessed dexterity) was evaluated with a self-report questionnaire. Results Both the IG (n = 58) and the CG (n = 68) improved their performance after each training session (p < 0.001) but with notable differences between sessions. Whereas the CG significantly improved their performance from t0 –t1 (p < 0.05), DIKS shortened practical exercise time by 58% so that the IG outperformed the CG from t1 -t2, (p < 0.05). High self-assessed motivation and dexterity associated with significantly better performance (p < 0.05). Male participants demonstrated significantly higher overall performance (p < 0.05). Conclusion Mental exercises like DIKS can improve laparoscopic performance and shorten practice times. Given the limited exposure of surgical residents to simulator training, implementation of mental exercises like DIKS is highly recommended. Gender, self-assessed dexterity, and motivation all appreciably influence performance in laparoscopic training. KW - laparoscopic skills KW - teaching methods KW - deconstruction into key steps KW - laparoscopic course Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-323969 VL - 36 IS - 12 ER - TY - JOUR A1 - Habarta, Johanna A1 - Jordan, Martin A1 - Meffert, Rainer A1 - Huflage, Henner A1 - Schmalzl, Jonas T1 - Surgical management of a traumatic elbow dislocation with disruption of the brachial artery. Case report JF - Obere Extremität N2 - Background Dislocations of the elbow are the second most common dislocations of humeral joints following the shoulder. Besides numerous possible concomitant injuries of the collateral ligaments or the extensor or flexor apparatus, an accompanying disruption of the brachial artery is a rare occurrence. In the following, such a case is presented and discussed. Method A 70-year-old woman sustained a closed posterior elbow dislocation with accompanying disruption of the brachial artery due to a fall in a domestic environment. Pulselessness of the radial artery led to a computed tomography angiography being performed, which confirmed the diagnosis. Direct operative vascular reconstruction with a vein insert was carried out. Due to strong swelling of the soft tissue, other examinations of the elbow could not be performed initially. A redislocation a few days later led to an operative stabilization of the elbow joint. Results The final consultation 4 months postoperatively showed a stable, centered elbow joint and a normal perfusion of the affected arm. The elbow function was good with a range of motion of 0/0/110° of extension/flexion. Conclusion An elbow dislocation is a complex injury. An accurate clinical examination of possible concomitant injuries is important and should be repeated in the first few days after the occurrence. Vascular reconstruction should be performed immediately. In the case of persistent joint instability, an operative stabilization is indicated and may be supported by a hinged external fixator. N2 - Hintergrund Eine Luxation des Ellenbogens stellt die zweithäufigste Luxation des menschlichen Körpers dar. Neben verschiedenen möglichen Begleitverletzungen im Bereich des Kapsel-Band-Apparats und der Sehnenansätze ist eine Abrissverletzung der A. brachialis eine Seltenheit. Im Folgenden wird ein solcher Fall präsentiert und diskutiert. Methoden Eine 70 Jahre alte Frau stürzte im häuslichen Umfeld und erlitt eine geschlossene Luxation des linken Ellenbogens mit begleitendem Abriss der A. brachialis. Fehlende Pulse der A. radialis führten zur Zuverlegung und zur Anfertigung einer computertomographiegesteuerten Angiographie, welche die Diagnose bestätigte. Die operative Gefäßrekonstruktion mittels Veneninterponat erfolgte sofort. Aufgrund stark geschwollener Weichteilverhältnisse waren weitere Untersuchungen des Ellenbogengelenks zunächst nicht möglich. Ein Reluxationsereignis einige Tage nach dem Unfall veranlasste zu weiterführender Diagnostik und operativer Stabilisierung des Ellenbogens. Ergebnisse Die Nachuntersuchung 4 Monate postoperativ zeigte ein stabiles, zentriertes Ellenbogengelenk, eine regelrechte Durchblutung des betroffenen Arms sowie eine gute Ellenbogenfunktion mit einem Bewegungsausmaß von 0/0/110° Extension/Flexion. Schlussfolgerung Eine Luxation des Ellenbogens ist eine komplexe Verletzung. Eine sorgfältige klinische Untersuchung aller möglichen Begleitverletzungen ist wichtig und sollte in den ersten Tagen mehrmals wiederholt werden. Gefäßverletzungen sollten sofort operativ behandelt werden. Bei persistierenden Gelenkinstabilitäten und Reluxationstendenzen ist eine operative Stabilisierung des Gelenks durchzuführen, welche durch die Anlage eines Bewegungsfixateurs unterstützt werden kann. T2 - Chirurgische Versorgung einer traumatisch bedingten Ellenbogenluxation mit Riss der A. brachialis. Fallbericht KW - elbow joint KW - vascular reconstruction KW - orthopedic surgery KW - joint instability KW - hinged external fixator KW - Ellenbogengelenk KW - Vaskuläre Rekonstruktion KW - Orthopädische Chirurgie KW - Gelenkinstabilität KW - Bewegungsfixateur Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-323972 SN - 1862-6599 VL - 17 IS - 4 ER - TY - JOUR A1 - Bachfischer, Andreas A1 - Barbosa, Martha Cecilia A1 - Rojas, Angel Alberto Riveras A1 - Bechler, Reinaldo A1 - Schwienhorst-Stich, Eva-Maria A1 - Kasang, Christa A1 - Simmenroth, Anne A1 - Parisi, Sandra T1 - Implementing community based inclusive development for people with disability in Latin America: a mixed methods perspective on prioritized needs and lessons learned JF - International Journal for Equity in Health N2 - Background Research on the needs of people with disability is scarce, which promotes inadequate programs. Community Based Inclusive Development interventions aim to promote rights but demand a high level of community participation. This study aimed to identify prioritized needs as well as lessons learned for successful project implementation in different Latin American communities. Methods This study was based on a Community Based Inclusive Development project conducted from 2018 to 2021 led by a Columbian team in Columbia, Brazil and Bolivia. Within a sequential mixed methods design, we first retrospectively analyzed the project baseline data and then conducted Focus Group Discussions, together with ratings of community participation levels. Quantitative descriptive and between group analysis of the baseline survey were used to identify and compare sociodemographic characteristics and prioritized needs of participating communities. We conducted qualitative thematic analysis on Focus Group Discussions, using deductive main categories for triangulation: 1) prioritized needs and 2) lessons learned, with subcategories project impact, facilitators, barriers and community participation. Community participation was assessed via spidergrams. Key findings were compared with triangulation protocols. Results A total of 348 people with disability from 6 urban settings participated in the baseline survey, with a mean age of 37.6 years (SD 23.8). Out of these, 18 participated within the four Focus Group Discussions. Less than half of the survey participants were able to read and calculate (42.0%) and reported knowledge on health care routes (46.0%). Unemployment (87.9%) and inadequate housing (57.8%) were other prioritized needs across countries. Focus Group Discussions revealed needs within health, education, livelihood, social and empowerment domains. Participants highlighted positive project impact in work inclusion, self-esteem and ability for self-advocacy. Facilitators included individual leadership, community networks and previous reputation of participating organizations. Barriers against successful project implementation were inadequate contextualization, lack of resources and on-site support, mostly due to the COVID-19 pandemic. The overall level of community participation was high (mean score 4.0/5) with lower levels in Brazil (3.8/5) and Bolivia (3.2/5). Conclusion People with disability still face significant needs. Community Based Inclusive Development can initiate positive changes, but adequate contextualization and on-site support should be assured. KW - community participation KW - peer support KW - leprosy KW - community leader KW - community based rehabilitation KW - South America KW - empowerment KW - participative implementation research KW - work inclusion KW - health access Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-357261 VL - 22 ER - TY - JOUR A1 - Krenzer, Adrian A1 - Heil, Stefan A1 - Fitting, Daniel A1 - Matti, Safa A1 - Zoller, Wolfram G. A1 - Hann, Alexander A1 - Puppe, Frank T1 - Automated classification of polyps using deep learning architectures and few-shot learning JF - BMC Medical Imaging N2 - Background Colorectal cancer is a leading cause of cancer-related deaths worldwide. The best method to prevent CRC is a colonoscopy. However, not all colon polyps have the risk of becoming cancerous. Therefore, polyps are classified using different classification systems. After the classification, further treatment and procedures are based on the classification of the polyp. Nevertheless, classification is not easy. Therefore, we suggest two novel automated classifications system assisting gastroenterologists in classifying polyps based on the NICE and Paris classification. Methods We build two classification systems. One is classifying polyps based on their shape (Paris). The other classifies polyps based on their texture and surface patterns (NICE). A two-step process for the Paris classification is introduced: First, detecting and cropping the polyp on the image, and secondly, classifying the polyp based on the cropped area with a transformer network. For the NICE classification, we design a few-shot learning algorithm based on the Deep Metric Learning approach. The algorithm creates an embedding space for polyps, which allows classification from a few examples to account for the data scarcity of NICE annotated images in our database. Results For the Paris classification, we achieve an accuracy of 89.35 %, surpassing all papers in the literature and establishing a new state-of-the-art and baseline accuracy for other publications on a public data set. For the NICE classification, we achieve a competitive accuracy of 81.13 % and demonstrate thereby the viability of the few-shot learning paradigm in polyp classification in data-scarce environments. Additionally, we show different ablations of the algorithms. Finally, we further elaborate on the explainability of the system by showing heat maps of the neural network explaining neural activations. Conclusion Overall we introduce two polyp classification systems to assist gastroenterologists. We achieve state-of-the-art performance in the Paris classification and demonstrate the viability of the few-shot learning paradigm in the NICE classification, addressing the prevalent data scarcity issues faced in medical machine learning. KW - machine learning KW - deep learning KW - endoscopy KW - gastroenterology KW - automation KW - image classification KW - transformer KW - deep metric learning KW - few-shot learning Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-357465 VL - 23 ER -