TY  - JOUR
A1  - Holzapfel, Boris Michael
A1  - Prodinger, Peter M.
A1  - Pilge, Hakan
A1  - Banke, Ingo J.
A1  - Bürklein, Dominik
A1  - Miethke, Thomas
A1  - Gradinger, Reiner
T1  - Acute Osteomyelitis of the Humerus mimicking Malignancy: Streptococcus pneumoniae as Exceptional Pathogen in an Immunocompetent Adult
JF  - BMC Infectious Diseases
N2  - Background

Chronic osteomyelitis due to direct bone trauma or vascular insufficiency is a frequent problem in orthopaedic surgery. In contrast, acute haematogenous osteomyelitis represents a rare entity that almost exclusively affects prepubescent children or immunodeficient adults.

Case Presentation

In this article, we report the case of acute pneumococcal osteomyelitis of the humerus in an immunocompetent and otherwise healthy 44-year-old male patient presenting with minor inflammation signs and misleading clinical features.

Conclusions

The diagnosis had to be confirmed by open biopsy which allowed the initiation of a targeted therapy. A case of pneumococcal osteomyelitis of a long bone, lacking predisposing factors or trauma, is unique in adults and has not been reported previously.
KW  - Acute osteomyelitis
KW  - Haematogenous
KW  - Long bones
KW  - Immunodeficiency
KW  - Osteomyelitis of the humerus
Y1  - 2013
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-95790
ER  - 
TY  - JOUR
A1  - Holzapfel, Boris Michael
A1  - Rechl, Hans
A1  - Lehner, Stefan
A1  - Pilge, Hakan
A1  - Gollwitzer, Hans
A1  - Steinhauser, Erwin
T1  - Alloplastic Reconstruction of the Extensor Mechanism after Resection of Tibial Sarcoma [Research Article]
N2  - Reconstruction of the extensor mechanism is essential for good extremity function after endoprosthetic knee replacement following tumor resection. Only a few biological methods have been able to reliably restore a functional extensor mechanism, but they are often associated with significant complication rates. Reattachment of the patellar tendon to the prosthesis using an alloplastic patellar ligament (Trevira cord) can be an appropriate alternative. In vivo and in vitro studies have already shown that complete fibrous ingrowth in polyethylene chords can be seen after a period of six months. However, until now, no biomechanical study has shown the efficacy of an alloplastic cord and its fixation device in providing sufficient stability and endurance in daily life-activity until newly formed scar tissue can take over this function. In a special test bench developed for this study, different loading regimes were applied to simulate loads during everyday life. Failure loads and failuremodes were evaluated. The properties of the cord were compared before and after physiological conditioning. It was shown that rubbing was the mode of failure under dynamic loading. Tensile forces up to 2558N did not result in material failure. Thus, using an artificial cord together with this fixation device, temporary sufficient stable fixation can be expected.
KW  - Medizin
Y1  - 2011
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-69072
ER  -