TY  - JOUR
A1  - Heinsen, Helmut
A1  - Heinsen, Y. L.
T1  - Cerebellar capillaries: qualitative and quantitative observations in young and senile rats
N2  - Ultrastructural changes including reduced electron density, reduction in polysemes and cisternae of rough endoplasmic reticulum occur in the cytoplasrn of endothelial cells and pericytes in the cerebellar cortex of senile virgin female Han: WIST-rats in cornparison to 3-month old virgin rats. Processes of pericytes cover less of the capillary surface in the cerebellar cortex of senile rats; moreover, arithmetic and harmonic mean thickness of the endothelium and relative volume of mitochondria in endothelial cells and pericytes are reduced, w hereas the luminal diameter of the capillaries, harmonic and arithmetic mean thickness of pericytes and their processes and of the basal laminae between endothelial cells and astrocytes (abbreviated BAL 1), pericytes and astrocytes (BAL 2) and endothelial cells and pericytes (BAL 3) increase. The increase in harmonic mean thickness of the basal laminae is statistically significant (α<=0.05) and compensates for a decrease in thickness of capillary endothelium. Consequently, the total barrier mass and thickness of cerebellar cortical capillaries in senile animals is higher than in young individuals.
KW  - Medizin
KW  - Capillaries
KW  - Blood-brain barrier
KW  - Quantitative anatomy
KW  - Cerebellar cortex
KW  - Senile rats
Y1  - 1983
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59924
ER  - 
TY  - JOUR
A1  - Heinsen, Helmut
A1  - Heinsen, Y. L.
A1  - Beckmann, H.
A1  - Gallyas, F.
A1  - Haas, S.
A1  - Scharff, G.
T1  - Laminar neuropathology in Alzheimer's disease by a modified Gallyas impregnation
N2  - No abstract available
KW  - Medizin
KW  - Alzheimer-Krankheit
Y1  - 1989
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59933
ER  - 
TY  - JOUR
A1  - Heinsen, Helmut
A1  - Heinsen, Y. L.
T1  - Quantitative studies on regional differences in Purkinje cell dendritic spines and parallel fiber synaptic density
N2  - No abstact available
KW  - Medizin
KW  - Cerebellar cortex
KW  - Albino rats
KW  - Quantitative anatomy
KW  - Purkinje cells
KW  - Spines
KW  - Parallel fiber synapses
KW  - Regional differences
Y1  - 1983
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-59917
ER  - 
TY  - JOUR
A1  - Heinsen, Helmut
A1  - Heinsen, Y. L.
T1  - Regionale Unterschiede der numerischen Purkinje-Zell-Dichte in Kleinhirnen von Albinoratten zweier Stämme
N2  - The total number and the number of Purkinje cells per square millimeter of the surface of the cerebellar granular layer were measured in albino rats from two strains: Chbb-THOM-Wist and Han: SPRD. The total number of the Purkinje cells in the cerebellar vermian lobules L land L X with the exception of cells in the lobules VIb + c did not. differ significantly. Statistically significant differences were found between the individuals of the two rat strains and within single lobules of the cerebella concerning the cell density of Purkinje cells per square millimeter surface of the granular layer. The results suggest heterogeneity of the cerebellar cortex between cerebellar lobules and between albino rats derived from different strains.
KW  - Albinoratten
KW  - Purkinje-Zellen
KW  - Quantitative Anatomie
KW  - Albino rats
KW  - Purkinje cells
KW  - Quantitative anatomy
Y1  - 1983
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45752
ER  - 
TY  - JOUR
A1  - Heinsen, Helmut
A1  - Heinsen, Y. L.
T1  - Serial thick, frozen, gallocyanin stained sections of human central nervous system
N2  - A rapid method for macroscopic and microscopic investigation of human CNS is proposed. After fonnalin fixation, gelatin or agarose embedding, and cryoprotective treatment, frozen human spinal cords, brainstems, or hemispheres can be serially cut into 0.7 mm thick slices. Stained with gallocyanin-chromalum, these slices facilitate cytoarchitectonic, neuropathologic, and quantitative examination. Regions of interest from parallel fonnalin-stored unstained slices can be embedded into paraffin and stained by any irnrnunocytologic and histologic stain compatible with fonnalin fixation and paraffin embedding.
KW  - CNS
KW  - comparative anatomy
KW  - cytoarchitectonics
KW  - neuroimaging
KW  - neuropathology
KW  - Nissl stain
KW  - quantitative anatomy
Y1  - 1991
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-45741
ER  -