TY  - THES
A1  - Hacker, Dorothee
T1  - Prospektiv randomisierte Untersuchungen zum klinischen Outcome nach Knierevisionen mit den Endoprothesen „EnduRo“ im Vergleich zur Prothese „Endo-Modell“
T1  - Clinical Outcome of two rotating hinge prostheses designs in revision total knee arthroplasty – a prospective randomized study
N2  - Aufgrund des demographischen Wandels mit einer zunehmend älter werdenden Bevölkerung ist die Zahl der Knieprothesen und vor allem auch der Revisionsoperationen in den letzten Jahren deutlich gestiegen. Mit ebenfalls zunehmendem medizinischem Anspruch wurden die bestehenden Prothesenmodelle stetig weiter entwickelt. 
Ziel der vorliegenden Studie war es, in einer prospektiv angelegten einfach verblindeten Studie zwei verschiedene Rotating-Hinge-Revisionsprothesen unterschiedlicher Hersteller miteinander zu vergleichen und sie auf ihr klinisches Outcome zu überprüfen.
Von Juni 2012 bis Mai 2013 wurden insgesamt 25 Patienten in die Studie aufgenommen und dann bis zu 12 Monate nach erfolgter Revisionsoperation nachuntersucht. Die Zuteilung der Prothesenarten erfolgte randomisiert, sodass 13 Patienten die Prothese „EnduRo“ und 12 Patienten die Prothese „Endo-Modell“ erhielten. Als Vergleichswerte wurden klinische Scores herangezogen.
In der Untersuchung zeigten beiden Vergleichsgruppen insgesamt eine deutliche Schmerzreduktion sowie eine Funktionsverbesserungen in allen erhobenen Scores. Zwar erreichten die Patienten der Gruppe „Endo-Modell“ etwas höhere Punktwerte, jedoch waren die Unterschiede im Vergleich zur Patientengruppe „EnduRo“ im durchgeführten Zweistichproben-T-Test nicht statistisch signifikant.
N2  - The number of revision surgerys of the knee is increasing due to demographic change and higher life expectancy. Therefore the development and constant improvement of prosthesis design is essential. Aim of this study was to compare the clinical outcome of two rotating hinge prostheses (EnduRo and Endo-Model).
Twentyfive patients with the indication for a total knee arthroplasty replacement because of ligament instability were prospectively randomised to either the Link Endo-Model (n = 12) or the EnduRo (n = 13). 
Clinical Scores (American Knee Society Score, Oxford Knee Score, Visual Analog Scale and SF-36) were evaluated pre-operatively and up to twelve months postoperatively. 
Although both prostheses models showed significant improvements as well in function scores as in pain reduction there was a slight advantage in favor of the Endo-Model.
KW  - Kniegelenk
KW  - Kniegelenkprothese
KW  - Vergleichsstudie
KW  - Total knee arthroplasty
KW  - Link Endo-Model
KW  - EnduRo
KW  - Knievrevision
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-215658
ER  - 
TY  - JOUR
A1  - Steinert, Andre F.
A1  - Rudert, Maximilian
A1  - Sieker, Jakob T.
T1  - "Symptomatic loosening  of a total knee arthroplasty caused by a tibial chondrosarcoma – a case report"
N2  - Premature implant loosening following total knee arthroplasty (TKA) can have several causes. In this article we report on a rare case of a 74 year old male patient suffering tibial component loosening 14 month after primary TKA. The patient did neither have any malignancies nor joint arthroplasty before. Upon clinical examination the range of motion in the diseased knee was painfully restricted to 80° of knee flexion, with the patient increasingly suffering sleeping and resting pain, and also at weight bearing. In standard radiographs, loosening of the TKA due to a large osteolysis at the tibial component was evident. Local computed tomography (CT) of the right knee revealed loosening of the tibial component due to a presumably malign bone tumor. For determination of the final diagnosis a representative biopsy of the tumor was taken by open surgery prior to the tumor resection. Histopathologic evaluation of the biopsy revealed a periprosthetic myxoid chondrosarcoma of the proximal tibia. Pre-operative staging examination included CT scans of lung and abdomen, as well as a bone scintigraphy which revealed no signs of tumor metastasis in the body. Surgical management comprised wide tumor resection and implantation of a hinged tumor knee arthroplasty with replacements of the distal femur and proximal tibia, as well as a patella tendon replacement using a synthetic ligament. Revision surgery was necessary twice due to impaired wound healing and critical soft tissue coverage, and treatment included a gastrocnemius muscle flap with skin mesh graft covering. Unfortunately long-term follow-up examinations could not be obtained, as the patient deceased due to an alveolitis during rehabilitation. In summary, the specifics of this rare case of aseptic TKA loosening, and the unusual circumstances of chondrosarcoma diagnosis and treatment are informative for those providing surgical treatment of similar cases.
KW  - Total knee arthroplasty
KW  - Bone tumor
KW  - Chondrosarcoma
KW  - Aseptic loosening
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-110341
ER  -