TY  - CHAP
A1  - Dandekar, Thomas
A1  - Argos, P.
T1  - Genetic algorithms as a new tool to study protein stability
N2  - No abstract available
Y1  - 1993
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29990
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Argos, P.
T1  - Drug assay using antibody mimics made by molecular imprinting
N2  - No abstract available
Y1  - 1993
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-30003
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Argos, P.
T1  - Potential of genetic algorithms in protein folding and protein engineering simulations
N2  - No abstract available
Y1  - 1992
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29974
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Argos, P.
T1  - Three-dimensional structure of the 67k N-terminal Fragment of E.coli DNA Topoisomerase I
N2  - No abstract available
Y1  - 1994
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29836
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Argos, P.
T1  - Folding the main chain of small proteins with the genetic algorithm
N2  - No abstract available
Y1  - 1994
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29847
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Argos, P.
T1  - The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted \(\alpha\)-helices: Crystal structure of the protein DNA-complex
N2  - No abstract available
Y1  - 1993
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29866
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Argos, Patrick
T1  - Amiloride-sensitive epithelial Na\(^+\) channel is made of three homologous subunits
N2  - No abstract available
Y1  - 1994
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29734
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Argos, Patrick
T1  - A novel heterodimeric cysteine protease is required for interleukin 1ß processing in monocytes
N2  - No abstract available
Y1  - 1992
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29986
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Argos, Patrick
T1  - Successive action of DnaK, DnaJ and GroEL along the pathway of chaperone-mediated protein folding
N2  - No abstract available
Y1  - 1992
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29814
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Argos, Patrick
T1  - Chaperonin-mediated protein folding at the surface of groEL through a "molten globule" intermediate
N2  - No abstract available
Y1  - 1991
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29939
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Bencurova, Elena
A1  - Osmanoglu, Özge
A1  - Naseem, Muhammad
T1  - Klimapflanzen und biologische Wege zu negativen Kohlendioxidemissionen
JF  - BIOspektrum
N2  - Climate plants are critical to prevent global warming as all efforts to save carbon dioxide are too slow and climate disasters on the rise. For best carbon dioxide harvesting we compare algae, trees and crop plants and use metagenomic analysis of environmental samples. We compare different pathways, carbon harvesting potentials of different plants as well as synthetic modifications including carbon dioxide flux balance analysis. For implementation, agriculture and modern forestry are important.
KW  - Klimapflanzen
KW  - Klimawandel
KW  - Klimaneutralität
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-270067
SN  - 1868-6249
VL  - 27
IS  - 7
ER  - 
TY  - GEN
A1  - Dandekar, Thomas
A1  - Dandekar, G.
T1  - Schlange als Attribut des Äskulap
N2  - No abstract available
Y1  - 1994
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29822
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Eisenreich, Wolfgang
T1  - Host-adapted metabolism and its regulation in bacterial pathogens
JF  - Frontiers in Cellular and Infection Microbiology
N2  - No abstract available.
KW  - bacterial pathogens
KW  - enteric pathogens
KW  - metabolism
KW  - host-pathogen adaption
KW  - isotopolog profiling
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-196876
SN  - 2235-2988
VL  - 5
IS  - 28
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Fieselmann, Astrid
A1  - Fischer, Eva
A1  - Popp, Jasmin
A1  - Hensel, Michael
A1  - Noster, Janina
T1  - Salmonella—how a metabolic generalist adopts an intracellular lifestyle during infection
JF  - Frontiers in Cellular and Infection Microbiology
N2  - The human-pathogenic bacterium Salmonella enterica adjusts and adapts to different environments while attempting colonization. In the course of infection nutrient availabilities change drastically. New techniques, “-omics” data and subsequent integration by systems biology improve our understanding of these changes. We review changes in metabolism focusing on amino acid and carbohydrate metabolism. Furthermore, the adaptation process is associated with the activation of genes of the Salmonella pathogenicity islands (SPIs). Anti-infective strategies have to take these insights into account and include metabolic and other strategies. Salmonella infections will remain a challenge for infection biology.
KW  - regulation
KW  - virulence
KW  - "-omics"
KW  - metabolism
KW  - Salmonella-containing vacuole (SCV)
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-120686
SN  - 2235-2988
VL  - 4
IS  - 191
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Fieselmann, Astrid
A1  - Fischer, Eva
A1  - Popp, Jasmin
A1  - Hensel, Michael
A1  - Noster, Janina
T1  - Salmonella - how a metabolic generalist adopts an intracellular lifestyle during infection
JF  - Frontiers in Cellular and Infection Microbiology
N2  - The human-pathogenic bacterium Salmonella enterica adjusts and adapts to different environments while attempting colonization. In the course of infection nutrient availabilities change drastically. New techniques, "-omics" data and subsequent integration by systems biology improve our understanding of these changes. We review changes in metabolism focusing on amino acid and carbohydrate metabolism. Furthermore, the adaptation process is associated with the activation of genes of the Salmonella pathogenicity islands (SPIs). Anti-infective strategies have to take these insights into account and include metabolic and other strategies. Salmonella infections will remain a challenge for infection biology.
KW  - enterica serovar Typhimurium
KW  - bacterial invasion
KW  - mouse model
KW  - defenses
KW  - regulation
KW  - "-omics"
KW  - virulence
KW  - Salmonella-containing vacuole (SCV)
KW  - metabolism
KW  - nitric oxide
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-149029
VL  - 4
IS  - 191
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Fieselmann, Astrid
A1  - Popp, Jasmin
A1  - Hensel, Michael
T1  - Salmonella enterica: a surprisingly well-adapted intracellular lifestyle
JF  - Frontiers in Microbiology
N2  - The infectious intracellular lifestyle of Salmonella enterica relies on the adaptation to nutritional conditions within the Salmonella-containing vacuole (SCV) in host cells. We summarize latest results on metabolic requirements for Salmonella during infection. This includes intracellular phenotypes of mutant strains based on metabolic modeling and experimental tests, isotopolog profiling using (13)C-compounds in intracellular Salmonella, and complementation of metabolic defects for attenuated mutant strains towards a comprehensive understanding of the metabolic requirements of the intracellular lifestyle of Salmonella. Helpful for this are also genomic comparisons. We outline further recent studies and which analyses of intracellular phenotypes and improved metabolic simulations were done and comment on technical required steps as well as progress involved in the iterative refinement of metabolic flux models, analyses of mutant phenotypes, and isotopolog analyses. Salmonella lifestyle is well-adapted to the SCV and its specific metabolic requirements. Salmonella metabolism adapts rapidly to SCV conditions, the metabolic generalist Salmonella is quite successful in host infection.
KW  - Salmonella enterica
KW  - metabolism
KW  - Salmonella-containing vacuole
KW  - regulation
KW  - virulence
Y1  - 2012
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-123135
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Gramsch, Christian
A1  - Houghton, Richard A.
A1  - Schultz, Rüdiger
T1  - Affinity purification of \(\beta\)-endorphin-like material from NG108CC15 cells by means of the monoclonal \(\beta\)-endorphin antibody 3-E7
N2  - No abstract available
Y1  - 1985
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29896
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Liang, Chunguang
A1  - Krüger, Beate
T1  - GoSynthetic database tool to analyse natural and engineered molecular processes
JF  - Database
N2  - An essential topic for synthetic biologists is to understand the structure and function of biological processes and involved proteins and plan experiments accordingly. Remarkable progress has been made in recent years towards this goal. However, efforts to collect and present all information on processes and functions are still cumbersome. The database tool GoSynthetic provides a new, simple and fast way to analyse biological processes applying a hierarchical database. Four different search modes are implemented. Furthermore, protein interaction data, cross-links to organism-specific databases (17 organisms including six model organisms and their interactions), COG/KOG, GO and IntAct are warehoused. The built in connection to technical and engineering terms enables a simple switching between biological concepts and concepts from engineering, electronics and synthetic biology. The current version of GoSynthetic covers more than one million processes, proteins, COGs and GOs. It is illustrated by various application examples probing process differences and designing modifications.
KW  - Bioinformatik
Y1  - 2013
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-97023
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Ribes, V.
A1  - Tollervey, David
T1  - Schizosaccharomyces pombe U4 small nuclear RNA closely resembles vertebrate U4 and is required for growth
N2  - No abstract available
Y1  - 1989
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29771
ER  - 
TY  - JOUR
A1  - Dandekar, Thomas
A1  - Schulz, R.
T1  - Evidence for the expression of peptides derived from three opioid precursors in NG 108CC15 hybrid cells
N2  - No abstract available
Y1  - 1987
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:20-opus-29909
ER  -